Clinical trials: Circadian Rhythm Sleep Disorder
Sleep Disorder
Evning Exposure to Computer Screen Disrupts Sleep, Attention and Biological Rhythms
Light exposure is on the rise in recent years. In large part because of unintentional illumination from screens that emit light directly into the eyes.
- Trial name
- NCT02957383
- Testing
- Wavelength, Intensity
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
Circadian Rhythm Sleep Disorder, Jet Lag Type
Facilitating Adjustment to Simulated Jet Lag
The aims of this study are to compare 3 different treatments for circadian adjustment to a laboratory protocol which will mimic westward air travel across 8 time zones.
- Trial name
- NCT05382923
- Testing
- Bright Light, Bright Light + Exercise + Melatonin, Control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Metabolic Dysfunction-Associated Steatotic Liver Disease, Overweight
Study of Grape Consumption in Adaptation to Seasonal Photoperiod
The goal of this randomized clinical trial is to learn whether consuming grapes during their natural season can help the body adapt to the shorter daylight hours of winter.
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Overweight, Obesity & Overweight
- Trial name
- PhotoGrape (NCT07886788)
- Testing
- Freeze-Dried Grape Powder, Plain Low-Fat Yogurt, Mediterranean-Style Dietary Guidance
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Preterm, Chronobiology
The Effect of Oral Feeding Model With a Chronobiological Approach in Neonates
The ideal food for healthy term babies as well as preterm babies and sick term babies is breast milk. There are many studies showing that the composition of breast milk can vary from mother to mother, according to the baby's…
- Conditions
- Preterm, Chronobiology, Human Milk/Breastfeeding, Bottle Feeding
- Trial name
- NCT06821672
- Testing
- Chronobiological Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Delayed Sleep Phase Syndrome
Are Patients Suffering From DSPS Show Compromising in Everyday Functions and Abilities Before Handling the Disorder?
The purpose of this study is to determine whether the known treatment for DSPS also improve the cognitive ability and mood of the patients.
- Trial name
- NCT02962037
- Testing
- Melatonin and light therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lilach Kemer
Sleep, Circadian Dysregulation
The Impact of Artificial Sunlight on Human Sleep and Circadian Rhythms
The purpose of this study is to examine, in healthy controls, whether LED lighting that has a color spectrum similar to that of sunlight is able to differentially impact mood, circadian rhythms, sleep, and behavior, as compared…
- Conditions
- Sleep, Circadian Dysregulation, Mood
- Trial name
- NCT03636360
- Testing
- Light
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Aerobic Exercise, Acute Exercise
Diurnal Variation of Exercise on Metabolic Health
The main objective of this project is to study the diurnal variation of the effect of exercise on glycemic metabolism and fat oxidation in humans.
- Conditions
- Aerobic Exercise, Acute Exercise, Circadian Rhythm Sleep-Wake Disorders, Unspecified Type, Glucose Metabolism
- Trial name
- DIVA (NCT05369715)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Dementia, Alzheimer Disease
Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders
The Multidisciplinary Expert System for the Assessment \& Management of Complex Brain Disorders (MES-CoBraD) is an interdisciplinary project combining Real-World Data (RWD) from multiple clinical and consumer sources through…
- Conditions
- Dementia, Alzheimer Disease, Epilepsy, Sleep Disorder
- Trial name
- MES-CoBraD (NCT05171725)
- Testing
- EEG,PSG, biosample collection (blood and CSF), neuropsychological testing
- Where
- 4 sites in Greece, Israel and 2 more
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Neurological Institute of Athens
Sleep Disorders, Circadian Rhythm
Evaluation of the Effects of Pharmaton Tablets on Mental Performance and Physical Fatigue in Nurses Working Night Shift
The general aim of this study is to assess the effects of Pharmaton® Caplets on mental performance and physical fatigue in nurses and nursing auxiliaries working night shifts
- Trial name
- NCT02199847
- Testing
- Pharmaton® Caplets
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Sleep Disorders, Circadian Rhythm
Nursing Activity and Quality of Hospitalized Patients' Sleep
This study is to determine the impact of night shift nurse's activity on patients' sleeping patterns in medical services including individual, clinical and environmental factors.
- Trial name
- SOMACTIV (NCT03370354)
- Testing
- Observational
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Delayed Sleep Phase Syndrome
Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their…
- Trial name
- CARRS-P2 (NCT04792697)
- Testing
- Increase morning bright light, Decrease evening blue light, Sleep Scheduling
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthcare Workers, Stress Level
Effects of VR-based Respiratory Training on Motor Reaction Time and Correctness, Stress Levels, Attention, Motor Skills, Postural Stability and Sleep Quality in Shift Healthcare Workers
This study investigates the effects of virtual reality (VR)-based respiratory training on various physiological and cognitive functions in shift-working healthcare professionals, including paramedics and nurses.
- Conditions
- Healthcare Workers, Stress Level, Emergency Department, Shift Work Sleep Disorder
- Trial name
- NCT06926257
- Testing
- Experimental group (B) - breathing training using VR, Experimental group (C) - breathing training using relaxation music
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Postpartum Women, Diabetes, Gestational
Circadian Clocks and Eating Patterns (Cohort)
For women of reproductive age, the overall postpartum weight retention (weight gain between pregnancies) plays a significant role in long-term obesity.
- Trial name
- NCT04642534
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Insomnia Disorder, Circadian Rhythm Sleep Disorder
The Sleep Clinic Outcome and Practice Study
The goal of this clinical trial is to explore the outcome and practice treatment for sleep-wake disturbances in a Sleep Clinic. The main questions it aims to answer are: What is the practice (timing and duration of treatment…
- Trial name
- SUP (NCT06669507)
- Testing
- Chronotherapy, Cognitive Behavioral Therapy for Insomnia
- Where
- Norway
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Depression; Major Depressive Disorder
Sleep/Wake Cycle and Depression: An Imaging and Treatment Study
16.2 million American adults are affected by depression each year. The investigators are studying the relationship between sleep/wake cycle and depression.
- Trial name
- NCT04350567
- Testing
- Sleep Deprivation
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Insomnia, Circadian Rhythm Disorders
Older Adults Exercising On Time
There are indications from epidemiological cohort studies and animal experiments that timing of physical activity (also referred as "chronoactivity"), irrespective of intensity, impacts health and disease.
- Trial name
- ON TIME (NCT06613958)
- Testing
- Physical activity timing
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Rapid Eye Movement Sleep Behavior Disorder
Sleep Profiles in REM Sleep Behavior Disorder
Rapid eye movement (REM) sleep behavior disorder (RBD) is a sleep disorder in which you act out dreams during REM sleep. Sleep disturbances are very common in RBD, where they negatively impact patients' quality of life and…
- Trial name
- NCT04886076
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronobiology Disorders
Circadian Health and Influential Factors
This study evaluates the quality of sleep of patients admitted to medical and intensive care units. All of them will have a clock placed to measure their circadian activity.
- Trial name
- CHRONOHOSPI (NCT04113876)
- Where
- Spain
- Volunteers
- 975 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Sleep Disorders, Circadian Rhythm
Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
Anesthesiology residency requires extended and overnight shifts, which may negatively impact the quantity and quality of sleep. Previous studies have investigated the effect of night float shift work on anesthesiology resident…
- Trial name
- NCT05701969
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Virginia