Clinical trials: Circulatory; Change
- Condition Circulatory; Change
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Atopic Dermatitis
A Study to Learn How Different Forms of the Study Medicine Called PF 08049820 Are Taken up Into the Bloodstream in Healthy Adults
The purpose of this study is to see how different forms of a medicine called PF-08049820 move through the body when taken by mouth.
- Trial name
- NCT07172321
- Testing
- PF-08049820 MR1, PF-08049820 MR2, PF-08049820 IR
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Anesthesia
Dose-Escalation Safety and Pharmacokinetic Study of K305
The purpose of this study is to determine the pharmacokinetics/pharmacodynamics and safety of a nasal spray containing the anesthetic drug tetracaine in combination with oxymetazoline
- Trial name
- NCT01304316
- Testing
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Renatus, LLC
Social Phobia
A Study To Compare Emotional Changes In Subjects With Social Anxiety Disorder
To compare by neuroimaging techniques the way Social Anxiety patients respond to public speaking before and after a drug administration
- Trial name
- NCT00470483
- Testing
- Paroxetine treatment during 8 weeks
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Peripheral Arterial Disease
Using SnapshotNIR With Provocative Leg Maneuver for PAD Assessment
The objective of this trial is to determine if Near-infrared spectroscopy (NIRS) can accurately evaluate the degree of Peripheral Arterial Disease (PAD) during a Provocative Elevation Maneuver of the Lower Extremity (PEMLE) test…
- Trial name
- NCT06237621
- Testing
- SnapshotNIR imaging
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kent Imaging Inc
Overweight, Obesity
Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance
Dietary protein is a key element of most effective weight loss regimens. This study will investigate the effects of consuming soy protein on body composition and cardiometabolic health within the context of an effective weight…
- Conditions
- Overweight, Obesity, Weight Loss
- Trial name
- NCT02380963
- Testing
- Colorado Diet with soy protein foods., Colorado Diet with monetary payments
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- DuPont Nutrition and Health
Stroke, Relatives
Survey of Lifelong Food and Nutrition Assistance (LIFANA) in Stroke Patients and Caregivers
Many elderly suffer from nutritional problems that can cause (or can be caused by) a number of complications such as weakened immune systems and chronic health conditions (diabetes type 2, high blood pressure, cardiovascular…
- Conditions
- Stroke, Relatives, Diet Modification
- Trial name
- NCT03635476
- Testing
- Qualitative interview study
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Cereneo AG
Circulatory; Change
Evaluating A Non-Invasive Tissue Perfusion Monitor
The Pedra perfusion system will be used to assess changes in perfusion in response to physiological stimuli. It will be compared to other standard diagnostics.
- Trial name
- NCT04630704
- Testing
- Pedra
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pedra Technology, PTE LTD
Cardiovascular Disease, Diabetes
Diet and Activity Promotion Among Older Working Adults
The trial will test whether the Alive email-delivered health behavior program can improve subjects' physical activity, fruits and vegetables and saturated/trans fats and added sugars.
- Conditions
- Cardiovascular Disease, Diabetes, Obesity, Aging
- Trial name
- ALIVE (NCT01233063)
- Testing
- Physical Activity and Diet Intervention via Alive2
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Berkeley Analytics, Inc.
Hypoalbuminemia, Heart Failure
Total Body Albumin Measurement Utilizing a Modification of the BVA 100 Blood Volume Analyzer
The DAXOR Corporation manufactures and distributes a blood volume analyzer. The analysis is based on the tracer dilution principle utilizing radioiodine labeled human serum albumin.
- Conditions
- Hypoalbuminemia, Heart Failure, Nephrosis, Cirrhosis
- Trial name
- NCT01542749
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Daxor Corporation
COPD, Asthma
Cardiorespiratory Diagnostic Study
This study uses a new breathing device called 'N-Tidal C' handset which measures breathing patterns. Investigators have found that people with cardiac and respiratory illnesses breathe out a gas, called carbon dioxide (CO2), in a…
- Conditions
- COPD, Asthma, Lung Cancer, Anemia
- Trial name
- CARES (NCT04939558)
- Testing
- N-Tidal C handset
- Where
- United Kingdom
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- TidalSense
Peripheral Arterial Disease, Diabetes Mellitus
The Use of HOVR Technology for Assessment of Blood Associated Parameters
Feasibility, usability and safety clinical study that is aimed at testing of the non-invasive VOTIS PedCheck system for measurement of changes in absorption of light in order to derive changes in perfusion and oxygen levels in…
- Trial name
- NCT05921461
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Votis Subdermal Imaging Technologies LTD
Hereditary Angioedema
Phase 1 Crossover Study in Healthy Subjects to Evaluate the PK Profile of KVD824 Following Single and Multiple Doses of Modified Release (MR) Formulations
This is a 3 part, phase 1 crossover study in healthy subjects to evaluate the pharmacokinetic profile of KVD824 following single and multiple doses of novel KVD824 modified-release formulations compared with a reference KVD824…
- Trial name
- NCT05118958
- Testing
- KVD824 Prototype 1 modified-release tablet, KVD824 Prototype 2 modified-release tablet, KVD824 Immediate-Release Capsule
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- KalVista Pharmaceuticals, Ltd.
Obesity
The ePass Clinical Trial for the Treatment of Obese Subjects
To evaluate the safety and efficacy of the endoscopically implanted ValenTx EndoPass™ System for treatment of adults with severe obesity.
- Trial name
- ePass (NCT02954016)
- Testing
- ePass
- Where
- 2 sites in Argentina, Mexico
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- ValenTx, Inc.
Cardiovascular Risk, Cardiovascular Disease Prevention
Digital Prevention Program With Telephonic Coaching
This study evaluates a digital health prevention program combining digital tools and structured telephonic coaching to support adult participants in improving health-related behaviors and well-being.
- Conditions
- Cardiovascular Risk, Cardiovascular Disease Prevention, Health Behavior Change, Lifestyle (Sedentary Behavior and Physical Activity)
- Trial name
- NCT07393646
- Testing
- Digital Health Platform, Telephonic Coaching
- Where
- France
- Volunteers
- 2,688 people, healthy volunteers welcome
- Sponsor
- Vivoptim Solutions
Circulatory; Change
Assessment of Circulatory Compromise With Ox-Imager Using a Vascular Occlusion Test Protocol
The objective of this study is to evaluate the performance of Modulated Imaging Inc.'s (MI) next generation Spatial Frequency Domain Imaging (SFDI) system to measure potential circulatory compromise.
- Trial name
- NCT03563105
- Testing
- The Ox-Imager Mini (Desaturation)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Modulated Imaging Inc.
Cardiac Event
PREVENT - Prospective Rhythm Event Surveillance in the ER With NetGuard
The purpose of this study is to determine the incidence of clinically significant rhythm and rate changes in ED patients who are not placed on conventional telemetry, and to test the user-friendliness of a automated clinician…
- Trial name
- PREVENT (NCT00750958)
- Testing
- NetGuard Automated Clinician Alert System
- Where
- 2 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Datascope Patient Monitoring
Change in Cognitive Function and Fatigue During Extended Performance of the Cognitive Demand Battery (CDB) at 1, 3 and 6 Hours Post Consumption, Change in Long Term Declarative Memory at 1, 3 and 6 Hours Post-intervention.
Plant Based Extracts and Cognition
Acute, randomized, placebo controlled, double blind, 4 arm crossover study to determine the effect of different combinations of plant based extracts on cognitive function and cerebral blood flow.
- Trial name
- CEOPTB (NCT02202629)
- Testing
- Beverage containing plant based extracts
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Cardiology: RR / QT
Selections of Subjects With Important Changes in Their Cardiac Repolarization Parameters for the Procurement of Skin and Blood Samples
The study main objective is to assess the changes in the ventricular repolarization (measure by the delta QTcf) after drug induced stimulation, compare to placebo, in order to identify subjects with extreme responses and…
- Trial name
- iQTEST (NCT01338441)
- Testing
- Erythromycin
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ectycell SASU
Cardiovascular Diseases
Heartmatters Challenge - First Responders
The purpose of this protocol is to observe whether providing the first responder population with a multi-tiered therapeutic lifestyle modification program, including regular blood testing, diet and telephonic lifestyle coaching…
- Trial name
- HMC-FR (NCT03322046)
- Testing
- Lifestyle Program
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Boston Heart Diagnostics
Acute Stroke, Transient Ischemic Attack
The Recurrence Study
The primarily goal of the research is to better understand progression of disease in patients who present with an acute stroke to the Hamad General Hospital (HGH) stroke and Transient Ischemic Attack (TIA) clinic.
- Trial name
- NCT03244215
- Testing
- Corneal Confocal Imaging, Magnetic resonance Imaging, Blood sample
- Where
- Qatar
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation