Clinical trials: Circulatory Collapse and Shock
Tooth Stability, Blood Flow
Effect of Shock Waves on Dental Parameters
This randomized clinical trial investigates the effect of the extracorporeal shockwave therapy (ESWT) on periodontal and endodontical parameters.
- Trial name
- NCT01600118
- Testing
- Extracorporeal shockwave therapy, No extracorporeal shockwave
- Where
- Austria
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Traumatic Shock, Hemorrhagic Shock
Prehospital Norepinephrine and Early Mortality in Traumatic Shock
The effect of early, prehospital norepinephrine use in patients with traumatic shock on mortality is unknown. Recent existing observational evidence from single system data (US, France, Japan) are conflicting.
- Conditions
- Traumatic Shock, Hemorrhagic Shock, Traumatic Brain Injury, Hypotension and Shock
- Trial name
- NCT04497155
- Testing
- Norepinephrine
- Volunteers
- 2,164 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Shock, Death
Polish Nationwide Register of Hospitalized Patients in Cardiac Intensive Care Units
Cardiac Intensive Care Units (CICUs) provide care for a diverse patient population. Understanding the clinical characteristics, analysis of treatment modalities, and prognosis of patients hospitalized in the CICU are important to…
- Conditions
- Shock, Death, Cardiac Intensive Care Unit, Treatment Complication
- Trial name
- POL-CICU (NCT06371677)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Sepsis, Sepsis and Septic Shock
Hemodynamic Venous Congestion Ultrasound (VExUS) by ICU Nurses in Sepsis Patients.
Sepsis is a serious condition where the body's immune response to infection overreacts, leading to organ damage and death. Venous congestion, a buildup of blood in the veins, can occur in sepsis and contribute to organ injury.
- Conditions
- Sepsis, Sepsis and Septic Shock, Sepsis at Intensive Care Unit, Intensive Care Nurses
- Trial name
- VEXIVAN (NCT07406750)
- Testing
- Education in performing hemodynamic diagnostic ultrasound of venous congestion, Hemodynamic diagnostic ultrasound of venous congestion
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Cardiovascular Diseases, Cardiovascular Diseases Risk
Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways
Cor360 is an observational study evaluating whether extended wearable electrocardiogram (ECG) data can support broad-spectrum cardiac phenotyping and risk assessment beyond conventional single-purpose ambulatory rhythm…
- Conditions
- Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular Abnormalities
- Trial name
- Cor360 (NCT07775976)
- Testing
- COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Aging
Acute Passive Heating in Healthy Older Adults
Aging is associated with a decline in cardiovascular health, cognitive function and losses in muscle strength, with half or more of those over age 65 suffering from two or more comorbidities (e.g., heart disease, type 2…
- Trial name
- NCT05622747
- Testing
- Passive heating
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Obstructive Sleep Apnea
BilatEral Hypoglossal Nerve StimulaTion for TreatmEnt of ObstRuctive SLEEP Apnoea With and Without Complete Concentric Collapse
The objective of this study is to explore the safety and performance of the Genio™ system in adult obstructive sleep apnoea (OSA) patients with and without complete concentric collapse of the soft palate over a period of 4.5…
- Trial name
- BETTER SLEEP (NCT03763682)
- Testing
- Genio(TM) bilateral hypoglossal nerve stimulation system
- Where
- 4 sites in Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nyxoah S.A.
Obstructive Sleep Apnea
Drug Induced Submental Ultrasound in Obstructive Sleep Apnea Patients
In this study, submental ultrasound during awake and simultaneous under Drug-induced sleep endoscopy is applied in the diagnostic workup of obstructive sleep apnea patients.
- Trial name
- NCT03285451
- Testing
- submental ultrasonography
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Circulatory Failure
Fluid Responsiveness Predicted by PtcO2 in Critically Ill Patients
Our goal was to study the feasibility of predicting fluid responsiveness by transcutaneous partial pressure of oxygen (PtcO2) in the critically ill patients.
- Trial name
- PtcO2-FR (NCT02083757)
- Where
- China
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Southeast University, China
Respiratory Failure, Circulatory Failure
ICU Background Early Awareness for Critical deterioratiON
The study will compare ICU sub-units, those with additional support of a clinician awareness system, ICU Beacon, and those receiving the standard of care.
- Conditions
- Respiratory Failure, Circulatory Failure, Mortality, Organ Dysfunction
- Trial name
- BEACON (NCT07119411)
- Testing
- ICU Beacon
- Where
- Switzerland
- Volunteers
- 1,962 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Heart Failure, Sepsis
Skeletal Muscle Oxygenation in Critically Ill
It is possible to measure skeletal muscle tissue oxygenation (StO2) using near infrared spectroscopy(NIRS). It is performed non invasively.
- Conditions
- Heart Failure, Sepsis, Septic Shock, Cardiogenic Shock
- Trial name
- NCT00384644
- Testing
- NiRS measurment of tissue oxygenation
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Inflammatory Response, Multi Organ Failure
Association of Cytokines With the Development of Complications in Burn and Toxic Epidermal Necrolysis (TENS) Patients
This study will involve blood draws to test for specific cytokines. The study goal is to gain a better understanding of the role of inflammatory response in the development of specific complications in burn and TENS patients.
- Conditions
- Inflammatory Response, Multi Organ Failure, Nosocomial Infection, Deep Vein Thrombosis
- Trial name
- NCT04252651
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Joseph M. Still Research Foundation, Inc.
Nasal Obstruction, Septal Defect
Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction?
The objective of this study is to compare the effectiveness of batten grafts plus septoplasty and turbinate reduction (intervention arm) compared to septoplasty and turbinate reduction alone (control arm), both in terms of…
- Conditions
- Nasal Obstruction, Septal Defect, Allergic Rhinitis, Nasal Polyps
- Trial name
- NCT05287841
- Testing
- Batten batten graft, Septoplasty, Inferior Turbinate Reduction
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Avascular Necrosis, Femoral Head Collapse
Avascular Necrosis (AVN) Long-Term Follow-up
Long-term follow-up of IDE patients for publication
- Trial name
- NCT00833430
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Coagulation Disorder, COVID 19 Associated Coagulopathy
Coagulation Disturbances in COVID-19 Septic Patients
Objective of this study was to determine the relationship between CAC and septic condition in COVID-19 critically ill patients. Data including age, sex, comorbidities, quick Sequential Organ Failure Assessment (qSOFA) score…
- Conditions
- Coagulation Disorder, COVID 19 Associated Coagulopathy, Sepsis, Septic Shock
- Trial name
- NCT05496816
- Testing
- CAC in septic patients
- Where
- Bosnia and Herzegovina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital Zenica