Clinical trials: Circulatory Disorders
Cardiac Rhythm Disorders, Urological Disorders
Product Surveillance Registry
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products.
- Conditions
- Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders
- Trial name
- PSR (NCT01524276)
- Where
- 402 sites in United States, Argentina and 39 more
- Volunteers
- 100,000 people
- Sponsor
- Medtronic
Chronic Conditions, Multiple, Diseases of the Circulatory System
National Institute for Health and Care Research Global Health Research Centre for Multiple Long-Term Conditions
Multiple Long-Term Conditions (MLTC), defined as the coexistence of two or more chronic conditions, is increasingly prevalent in India.
- Conditions
- Chronic Conditions, Multiple, Diseases of the Circulatory System, Diseases of the Respiratory System, Endocrine, Nutritional and Metabolic Diseases
- Trial name
- NIHR-GHRC MLTC (NCT07582380)
- Testing
- Electronic Decision Support System (EDSS), Assisted Telemedicine, Patient-facing app for self-management, supported by care coordination through Community Champions and Care Coordinators.
- Where
- 120 sites in India, Nepal
- Volunteers
- 3,600 people
- Sponsor
- Centre for Chronic Disease Control, India
Diseases of the Circulatory System, Diseases of the Respiratory System
Assessing Feasibility of a Digital Health Intervention for Multiple Long-Term Condition Care in Primary Health Settings in India and Nepal
This observational, non-randomized, single-arm pilot study aims to assess the acceptability, feasibility, usability, and implementation fidelity of a co-designed multi-component digital health intervention to support the…
- Conditions
- Diseases of the Circulatory System, Diseases of the Respiratory System, Endocrine, Nutritional and Metabolic Diseases, Mental, Behavioral and Neurodevelopmental Disorders
- Trial name
- NIHR GHRC MLTC (NCT07400133)
- Testing
- Electronic Decision Support System (EDSS), Assisted telemedicine, Patient facing mobile app and Community champions (Care coordinators)
- Where
- 6 sites in India, Nepal
- Volunteers
- 180 people
- Sponsor
- Centre for Chronic Disease Control, India
Chronic Pain, Circulatory Disorders
Cannabis Vs Opioids Pain Management Objective Testing Comparisons
Our purpose for the study is to find safer, less intrusive, better preforming non-addictive products, as an alternative therapy for pain relief and to help alleviate the opioid epidemic ongoing in America today.
- Trial name
- CVO (NCT03734731)
- Testing
- Monochromatic Infrared Photo Energy (MIRE), Transcutaneous Electrical Nerve Stimulation, Opioids
- Volunteers
- 1,000 people
- Sponsor
- American Association of Sensory Electrodiagnostic Medicine
Infectious Disease, Neoplasms
AnovaOS Network Powered Patient Registry
The objective of this study is the development, implementation and management of a registry of patient data that captures clinically meaningful, real-world, data on the diagnosis, nature, course of infection, treatment(s) and…
- Conditions
- Infectious Disease, Neoplasms, Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89), Endocrine, Nutritional and Metabolic Diseases (E00-E89)
- Trial name
- NCT05013944
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Anova Enterprises, Inc
Cerebral Circulatory Disorder
Capsaicin for Cerebral Perfusion Augmentation
To determine the effect of capsaicin upon serial transcranial Doppler (TCD) markers of cerebral blood flow (CBF). Methods Serial TCD testing in 30 participants with cerebrovascular risk factors. Capsaicin doses .66 and .99 μMol.
- Trial name
- CCPA (NCT05543837)
- Testing
- Capsaicin
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Instituto Mexicano del Seguro Social
Circulatory Failure, Fluid Volume Disorder
Volume Responsiveness Assesment After Propofol.
Patients in ICU who suffer from circulatory insufficiency, regardless the cause that require invasive hemodynamic monitoring. The aim of the study is to correlate stroke volume variation which predicts fluid responsiveness with…
- Conditions
- Circulatory Failure, Fluid Volume Disorder, Critical Illness
- Trial name
- NCT03917446
- Testing
- Propofol bolus
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
COVID19, ARDS
Follow-up of Critical COVID-19 Patients
The study will follow COVID-19 patients who required intensive care after 3-6 months and one year after discharge from the ICU with functional level as well as organ function to assess recovery after COVID-19.
- Conditions
- COVID19, ARDS, AKI, Circulatory Failure
- Trial name
- FUP-COVID (NCT04474249)
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Uppsala University
Disorder of Circulatory System
Coagulopathy and SIRS During ECC in Intensive Care
This observational clinical study investigates cellular and plasmatic activation markers as well as proteins involved in coagulation and inflammation in patients being connected to different extracorporeal circulation (ECC) and…
- Trial name
- NCT02352805
- Testing
- ECLS/ECC
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- University Hospital Tuebingen
Heart Failure, Circulatory Disorders Postprocedural Complication
Observational Hemodynamic Monitoring During LVAD Implantation Among Individuals With Advanced Heart Failure
The overall objective of this pilot analysis is to characterize the hemodynamic changes that occur during implantation of a left ventricular assist device (LVAD) in patients with advanced heart failure - specifically, how right…
- Conditions
- Heart Failure, Circulatory Disorders Postprocedural Complication, Cardiomyopathy, Congestive, Surgery
- Trial name
- BATMAN (NCT03464981)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Acute Kidney Injury Due to Circulatory Failure (Disorder)
The Effects of Oxiris on Systemic Inflammation and Endothelial dysFunction
CS-AKI occurring in 20% to 70% of cases depending of the type of cardiac surgery. The systemic inflammatory response is often observed and associated with increased risk of AKI.
- Trial name
- EOSIEF (NCT04257006)
- Testing
- oXiris membrane
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Circulatory Perfusion Disorder, Congenital Heart Disease
Early Use of Vasopressin in Post-Fontan Management
This is an investigator initiated, prospective, single-center, double-blinded, randomized, placebo-controlled trial of post-operative low dose vasopressin infusions as an early treatment of low systemic perfusion in pediatric…
- Conditions
- Circulatory Perfusion Disorder, Congenital Heart Disease, Single-ventricle
- Trial name
- VAMP (NCT03088345)
- Testing
- Vasopressin, Arginine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Morality, Hypothermic Circulatory Arrest Time
A Comparative Study of Different Hypothermic Circulatory Arrest Strategies on Aortic Surgery.
By comparing the clinical outcome of patients underwent different hypothermic circulatory arrest (mild hypothermic versus moderate hypothermic) during aortic arch surgery, this study aims to determine the optimal hypothermic…
- Conditions
- Morality, Hypothermic Circulatory Arrest Time, Aortic-cross Clamping Time, Cardiopulmonary Bypass Time
- Trial name
- NCT03454633
- Testing
- the temperature of hypothermic circulatory arrest
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xiaoping Fan. MD
Disorder of Circulatory System, Metabolic Disease
Investigation of Long-term Effects of CarelessTM on Microcirculation
Aim of the study is to investigate long-term effects of CarelessTM, a Mangifera indica fruit powder on microcirculation and endothelial function after supplementation of 4 weeks.
- Trial name
- NCT02588313
- Testing
- Mango fruit powder
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vital Solutions Swiss AG