Clinical trials: Circumcision
Circumcision, Male
A Study Comparing The Effect Of Local Application Of Polyfax Versus Coconut Oil On Outcome Of Plastibell Circumcision In A Tertiary Care Hospital
The goal of this clinical trial is to compare the frequency of post-circumcision complications (bleeding, infection, and delayed ring separation) time for ring separation and level of parental satisfaction following local…
- Trial name
- NCT07750093
- Testing
- agent used for local application
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Liaquat National Hospital & Medical College
Analgesia
Music as Analgesia During Neonatal Circumcision
Neonatal circumcision is one of the most frequently performed and more painful procedures. Sharara et al (2017) showed the combination of EMLA + Sucrose + Ring Block provides the highest standard of pain management.
- Trial name
- NCT04252313
- Testing
- Music
- Where
- Lebanon
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Anesthesia, Pediatric Circumcision
Analgesia for Pediatric Circumcision : Comparison of the Effectiveness of Pudendal Nerve Block to Penile Nerve Block
Medical or ritual circumcisions are frequent interventions in children. To provide the best comfort to the patients, the anesthetists use regional anesthesia.
- Trial name
- NCT04227561
- Testing
- Pudendal nerve block, Penile nerve block
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Children Who Need Circumcision
Assessment of Hemodynamic Response in Surgery of Circumcision in Children
The surgery stress relives systemic inflammatory response by hormones and adrenergic receptors. When the pro-inflammatory mediator is higher than anti-inflammatory response, the physiologic status is impaired and the patient is…
- Trial name
- NCT00943475
- Testing
- circumcision
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Pregnant, Healthy Females, Healthy Male Newborns
Use of Existing Fibroblast Cells to Convert to Induced Pluripotent Stem Cells
Induced pluripotent stem cells potentially may be useful in the future as an unlimited source of cells for transplantation. The major goal of the project is to develop human iPS cells from existing lines of fibroblasts that were…
- Trial name
- NCT00801372
- Where
- Israel
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Male Circumcision, HIV Prevention
Cohort Field Study to Assess the Safety and Efficacy of the PrePex Device for Non-Surgical Circumcision When Performed by Nurses
A range of observational and epidemiological studies have shown that the lifetime risk of HIV infection can be reduced by 70% through male circumcision.
- Trial name
- NCT01434628
- Testing
- PrePex™ device
- Where
- Rwanda
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Hydrocele, Spermatocele
Evaluating Patient Tolerability and Success for Penile and Scrotal Urologic Procedures Under Conscious Sedation: A Prospective Study
The goal of this observational study is to evaluate patient reported outcomes and tolerability of scrotal and penile urologic procedures under the administration of minimal conscious sedation.
- Conditions
- Hydrocele, Spermatocele, Varicocele, Epididymal Cyst
- Trial name
- NCT05617261
- Testing
- Conscious sedation
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Manitoba
Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia
Sacral Erector Spinae Plane Block Versus Penile Block For Analgesia In Pediatric Circumcision
Circumcision is one of the most frequently performed surgical procedures in childhood and is associated with significant postoperative pain.
- Conditions
- Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia, Regional Anaesthesia
- Trial name
- NCT07321717
- Testing
- Sacral Erector Spinae Plane Block, Penile Nerve Block (PNB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Male Circumcision
From Obstacles to Opportunities for Male Circumcision in Tanzania
Male circumcision has been demonstrated by three randomized trials to be a highly effective method of HIV prevention, leading the World Health Organization to recommend its widespread implementation.
- Trial name
- NCT02167776
- Testing
- Church-based teaching
- Where
- Tanzania
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Circumcision, Male
Gomco Versus Mogen: Which is Best? A Randomized Controlled Trial
The purpose of this study is to compare two commonly used circumcision clamps (Gomco and Mogen) to see which results in less neonatal pain.
- Trial name
- GMRT (NCT01726036)
- Testing
- Gomco Circumcision Clamp, Mogen Circumcision Clamp
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Male Circumcision, HIV Prevention
The Shang Ring: A Novel Male Circumcision Device for HIV Prevention
The purpose of this study is to evaluate the Shang Ring, a novel Chinese device for voluntary medical male circumcision, in order to improve the provision of male circumcision services for HIV prevention in Africa.
- Conditions
- Male Circumcision, HIV Prevention, HIV Infections
- Trial name
- ShangRing (NCT00993811)
- Testing
- Shang Ring circumcision
- Where
- Kenya
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
HIV Infections, Acquired Immunodeficiency Syndrome
Text Messaging to Improve Adherence to Clinic Visits and Reduce Early Resumption of Sexual Intercourse After Male Circumcision
Male circumcision (MC) reduces, by more than half, the risk of HIV-1 acquisition. WHO and UNAIDS recommend that "male circumcision should be recognized as an efficacious intervention for HIV prevention especially in countries and…
- Conditions
- HIV Infections, Acquired Immunodeficiency Syndrome, Circumcision, Male, Patient Compliance
- Trial name
- NCT01186575
- Testing
- Text Message
- Where
- Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Infections, Sexually Transmitted Infections
Uptake of Medical Male Circumcision Among Men With Sexually Transmitted Infections
The intervention includes provision of transport reimbursement for men who will undergo voluntary medical male circumcision (VMMC), intensified health education by a VMMC mobilizer and a male and female VMMC champion and use of a…
- Trial name
- VMMC-RITe (NCT04677374)
- Testing
- Standard of care, Intensified Health Education, SMS/telephonic Tracing
- Where
- Malawi
- Volunteers
- 2,242 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Medical Device Complication
Feasibility Study of PrePex Device When Performed on Early Infants & Children Male Population by Physicians
The PrePex is a WHO prequalified medical device for adult male circumcision for HIV prevention. The Government of Rwanda was the first country to implement the PrePex and acts as the leading Center of Excellence providing…
- Trial name
- RMC-06 (NCT02281461)
- Testing
- Male circumcision using a non-surgical device
- Where
- Rwanda
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Breastfeeding, Exclusive, Circumcision
Circumcision and Breastfeeding
1) To determine when the majority of male infants are being circumcised at 3 hospitals across the US (Brooke Army Medical Center, Naval Medical Center San Diego, and Dartmouth Hitchcock Medical Center.
- Trial name
- NCT03619369
- Testing
- Circumcision
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Male Circumcision
Evaluation of the AccuCirc for Early Infant Male Circumcision in Nyanza, Kenya
Male circumcision (MC) is an effective, research-tested, evidence-based HIV prevention strategy that is cost-saving. Randomized trials provide compelling evidence that MC reduces men's risk of heterosexually-acquired HIV-1…
- Trial name
- NCT02277795
- Testing
- AccuCirc
- Where
- Kenya
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Tonsillitis, Sleep Disordered Breathing
Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery
Opioids are an important component of post-operative pain management among children, but are often prescribed in excess and rarely disposed of appropriately.
- Conditions
- Tonsillitis, Sleep Disordered Breathing, Hernia, Hydrocele
- Trial name
- NCT03575377
- Testing
- Disposal Aid
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Nationwide Children's Hospital
Woman Abuse
Prevalence of Female Circumcision Among Young Women in Beni-Suef, Egypt
Female circumcision (FC) is a deeply-rooted practice in Egypt with deblitating physical and psychological consequences, however the previous two decades witnessed sincere efforts to counterfight this practice.
- Trial name
- FC (NCT03381612)
- Where
- Egypt
- Volunteers
- 3,353 people
- Sponsor
- Beni-Suef University
HIV Seropositivity
Evaluation of the PrePex Device for Rapid Scale-up of VMMC, Phase 3 Field Implementation Trial With HIV + Adult Males
This study will assess the safety of the PrePex device as applied to HIV positive men by assessing the rate of clinical adverse events.
- Trial name
- NCT03218839
- Testing
- PrePex male circumcision device
- Where
- Zimbabwe
- Volunteers
- 430 people
- Sponsor
- University of Washington
Pain, Circumcision
Acetaminophen and Post Circumcision Pain Control
Infants do not routinely receive acetaminophen for pain control after circumcision. This study will determine if acetaminophen is effective at controlling infant pain after circumcision using nerve block and oral dextrose.
- Trial name
- NCT02498483
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Columbia University