Clinical trials: Circumcision, Male
Behavior, Health
A RCT Promoting Voluntary Medical Male Circumcision
A parallel-group, non-blinded randomized controlled trial was conducted. Participants were uncircumcised heterosexual male sexually transmitted disease patients attending the four collaborative public sexually transmitted…
- Trial name
- NCT03414710
- Testing
- Health education booklet plus video plus brief counseling, Health education booklet only
- Where
- Hong Kong
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Male Circumcision
A Prospective Field Study: Introducing the Shang Ring in Routine Clinical Settings
Male Circumcision (MC) is the only new biomedical method to demonstrate consistent efficacy as an HIV prevention intervention in randomized controlled trials (WHO and UNAIDS, 2007), based on three randomized controlled trials in…
- Trial name
- NCT01567436
- Testing
- Shang Ring
- Where
- 2 sites in Kenya, Zambia
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- FHI 360
Preoperative Fasting, Perioperative Anxiety
Preoperative Fasting and Perioperative Outcomes in Children Undergoing Elective Circumcision
This prospective observational study aims to evaluate adherence to preoperative fasting guidelines and investigate the relationship between actual fasting durations, anxiety levels, and blood glucose levels in children aged 1-10…
- Conditions
- Preoperative Fasting, Perioperative Anxiety, Perioperative Hypoglycemia
- Trial name
- NCT07876583
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Burcu Ayvazoğlu
Surgical Technique
A Randomized Controlled Trial of Open Surgical vs. Minimally-invasive Voluntary Adult Male Circumcision
This proposed randomized controlled trial will provide important data which will inform and enable the Mozambican government and global health programs to more effectively scale-up circumcision services.
- Trial name
- NCT01688310
- Testing
- Gomco Clamp with Tissue Adhesive, Open surgical circumcision
- Where
- Mozambique
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade Católica de Moçambique
Circumcision
Circumcision With Use of Thermocautery and Histopathological Changes
Histo pathological changes that occurs in thermo cautery circumcision and the range of damage prepuce from thermal effect in comparison with scalpel circumcision
- Trial name
- NCT04092998
- Testing
- Thermocautery circumcision
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
HIV
Observational Study of Male Circumcision Using PrePex Device
The study will measure the incidence of moderate and severe adverse events (AEs) associated with PrePex procedures, including both procedural and post-procedure events, and all device-related incidents such as dislodgment.
- Trial name
- NCT01711411
- Testing
- PrePex device for male circumcision
- Where
- Kenya
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- FHI 360
Breastfeeding, Exclusive, Circumcision
Circumcision and Breastfeeding
1) To determine when the majority of male infants are being circumcised at 3 hospitals across the US (Brooke Army Medical Center, Naval Medical Center San Diego, and Dartmouth Hitchcock Medical Center.
- Trial name
- NCT03619369
- Testing
- Circumcision
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Anxiety, Pain, Postoperative
Nursing Intervention Program in the Management of Parental Anxiety and Infant Pain in the Surgical Process of Children to be Circumcised
Entering the hospital and waiting for surgery is a very stressful time for people. According to some studies, surgical interventions in children generate in family members concerns related to: anesthesia, fear of being harmed…
- Conditions
- Anxiety, Pain, Postoperative, Child Development
- Trial name
- NCT05387291
- Testing
- Intervention group, Control group
- Where
- Spain
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Universitat de Girona
Neonatal Male Circumcision
Feasibility, Acceptability, and Safety of Neonatal Male Circumcision in Lusaka, Zambia
In this study of neonatal male circumcision (NMC), the investigators will examine acceptability of among parents, feasibility of training providers and implementing services in various clinical settings, and the safety of service…
- Trial name
- NCT01115335
- Testing
- Neonatal male circumcision
- Where
- Zambia
- Volunteers
- 661 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Postoperative Analgesia
Comparison of the Effects of Sacral Erector Spinae Plane Block and Dorsal Penile Block on Postoperative Pain in Circumcision Procedures
Egypt performed circumcision in 2300 BC, although its origin is unknown. Some societies use circumcision for health, whereas others do it for religious and cultural reasons .
- Trial name
- NCT06843070
- Testing
- PENILE BLOCK ARM, SACRAL ESP BLOCK ARM
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Postoperative Delirium, Pediatric Anesthesia
Inflammatory Biomarkers and Postoperative Delirium in Pediatric Circumcision
Postoperative delirium may occur in children after general anesthesia, even following short procedures such as circumcision. Preoperative systemic inflammation has been associated with postoperative delirium in adults, but data…
- Conditions
- Postoperative Delirium, Pediatric Anesthesia, Inflammatory Biomarkers
- Trial name
- NCT07323485
- Testing
- Measurement of Preoperative Inflammatory Biomarkers
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Medical Male Circumcision
An Implementation Science Study Investigating Profiles of Men Interested in MMC
There are both supply and demand gaps in our understanding of how best to implement MMC services. In terms of supply of MMC services, there is a need to better understand what the best way is of efficiently accessing mature…
- Trial name
- Imbizo (NCT02352961)
- Testing
- Exclusive Intervention Strategy
- Where
- South Africa
- Volunteers
- 2,817 people, healthy volunteers welcome
- Sponsor
- The Aurum Institute NPC
Circumcision, Adolescents
Safety and Efficacy Study of Non-Surgical MC Device for Adolescent Male Population Including Contraindicated Subjects
A new Male Circumcision (MC) device, PrePex, has shown great promise as a way to radically shift the MC landscape. PrePex is an innovative circumcision device requiring no injected anesthesia, sutures, or sterile settings.
- Trial name
- NCT02581722
- Testing
- PrePex Device
- Where
- Rwanda
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Newborn; Infection, Disinfection
Preoperative Antiseptic in Newborn Circumcision Comparison of Povidone Iodine and Hypochlorous Acid Used
Comparison of Povidone iodine and Hypochlorous acid used as a Preoperative Antiseptic in Newborn Circumcision abstract Aim: Circumcision is one of the most common surgical procedures in all age groups.
- Conditions
- Newborn; Infection, Disinfection, Circumcision
- Trial name
- NCT05175027
- Testing
- hypochlorous acid
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Fear, Anxiety
Immersive Virtual Reality and Music During Circumcision in Children
The goal of this randomized controlled trial is to examine the effectiveness of immersive virtual reality (IVR) and music on children's anxiety, fear, and pain levels during circumcision surgery.
- Conditions
- Fear, Anxiety, Child
- Trial name
- NCT06255548
- Testing
- Immersive virtual reality group, Music group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Female Circumcision, Female Genital Mutilation/Cutting
A Community-based Participatory Intervention to Change Attitudes Towards Female Circumcision Among Somali Immigrants in Sweden
Female circumcision (FC) causes both immediate and long-term health consequences. In general, the more severe type of FC, the worse health consequences can be seen.
- Trial name
- NCT02335697
- Testing
- Attitude change towards female circumcision, No intervention
- Where
- Sweden
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Uppsala University
HIV Infections, Sexually Transmitted Infections
Uptake of Medical Male Circumcision Among Men With Sexually Transmitted Infections
The intervention includes provision of transport reimbursement for men who will undergo voluntary medical male circumcision (VMMC), intensified health education by a VMMC mobilizer and a male and female VMMC champion and use of a…
- Trial name
- VMMC-RITe (NCT04677374)
- Testing
- Standard of care, Intensified Health Education, SMS/telephonic Tracing
- Where
- Malawi
- Volunteers
- 2,242 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections, Herpes Genitalis
Effect of Male Circumcision on HIV Incidence (ANRS 1265)
Observational studies suggest that male circumcision may provide protection against HIV-1 infection. A randomized, controlled, intervention trial was conducted in a general population of South Africa to test this hypothesis.
- Conditions
- HIV Infections, Herpes Genitalis, Venereal Diseases
- Trial name
- NCT00122525
- Testing
- Male Circumcision
- Where
- South Africa
- Volunteers
- 3,274 people, healthy volunteers welcome
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Male Circumcision
Phase 4 Field Trial of the Unicirc Instrument With Tissue Adhesive
This is a field trial of the Unicirc instrument to excise the foreskin, plus use of cyanoacrylate tissue adhesive to seal the wound.
- Trial name
- Unicirc003 (NCT02091726)
- Testing
- Unicirc instrument plus cyanoacrylate tissue adhesive
- Where
- South Africa
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Simunye Primary Health Care
Pregnant, Healthy Females, Healthy Male Newborns
Use of Existing Fibroblast Cells to Convert to Induced Pluripotent Stem Cells
Induced pluripotent stem cells potentially may be useful in the future as an unlimited source of cells for transplantation. The major goal of the project is to develop human iPS cells from existing lines of fibroblasts that were…
- Trial name
- NCT00801372
- Where
- Israel
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization