Clinical trials: Circumcision
Circumcision
Effect of Mandala Coloring of Circumcised Children
The aim of this study was to determine the effect of mandala painting on fear, anxiety, emotional symptoms and postoperative pain of circumcised children.
- Trial name
- NCT06583187
- Testing
- Coloring a mandala picture
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Artvin Coruh University
HIV Infections, Herpesvirus 2, Human
Male Circumcision for HIV Prevention in Rakai, Uganda
Circumcision in HIV unifected men may reduce the likelihood of becoming infected with HIV, reduce sexually transmitted infections (STIs) in men, not engender increases in sexual risk behaviors, and be acceptable to men as a…
- Conditions
- HIV Infections, Herpesvirus 2, Human, Syphilis, Genital Diseases, Male
- Trial name
- NCT00425984
- Testing
- Adult male circumcision
- Where
- Uganda
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Posterior Urethral Valves
Efficacy and Safety of Circumcision Alone on Risk of Febrile Urinary Tract Infections in Boys With Posterior Urethral Valves: a Prospective Randomized Open-label Multicentric Trial Enriched With Historic Controls.
Boys with posterior urethral valves (PUV) are at increased risk of developing febrile urinary tract infections (fUTIs). As shown in the CIRCUP trial, circumcision plus antibiotic prophylaxis reduces the risk of FUTIs compared…
- Trial name
- CIRCUP 2 (NCT07527442)
- Testing
- Antibiotics strategy, Circumcision
- Where
- 13 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Bordeaux
Odor Levels of Study Arms
An Open Label, Blinded Assessor, Trial Comparing Odor Levels Due to Different Hygiene Methods With PrePexTM
The PrePex is a WHO prequalified medical device for adult male circumcision for HIV prevention. The Government of Rwanda was the first country to implement the PrePex and acts as the leading Center of Excellence providing…
- Trial name
- RMC-10 (NCT02153658)
- Testing
- Subjects cleaned the foreskin with soapy water using a syringe once a day., Subjects cleaned the foreskin with diluted chlorhexidine (1%) using a syringe once a day.
- Where
- Rwanda
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Regional Anesthesia
Comparison of Caudal Block and Retrolaminar Block for Circumcision
Primary Outcome: Analgesic Efficiency: The primary outcome is the comparison of the analgesic efficacy of the retrolaminar block (RL) versus caudal block (CB) based on postoperative pain scores measured by the FLACC score.
- Trial name
- NCT06584292
- Testing
- caudal block, Retrolaminar block
- Where
- Turkey (Türkiye)
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Circumcision
Alisklamp and Dorsal Slit Sleeve Circumcision
In this study the plan is to compare the circumcision performed with Alisklamp versus Dorsal Slit Sleeve method in terms of age, co-existing health conditions, surgery time, recovery period, tissue edema and bleeding…
- Trial name
- NCT06177834
- Testing
- Alisklamp, Dorsal slit circumcision technique
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Mustafa Azizoğlu
Circumcision, Male
Unicirc vs Open Surgical Circumcision
RCT of Unicirc under topical anesthetic w/ cyanoacrylate wound sealing vs. open surgical circumcision under local anesthetic with suturing.
- Trial name
- Unicirc004 (NCT02443792)
- Testing
- Unicirc with tissue adhesive, Open Surgical
- Where
- South Africa
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Simunye Primary Health Care
Male Circumcision
A Prospective Field Study: Introducing the Shang Ring in Routine Clinical Settings
Male Circumcision (MC) is the only new biomedical method to demonstrate consistent efficacy as an HIV prevention intervention in randomized controlled trials (WHO and UNAIDS, 2007), based on three randomized controlled trials in…
- Trial name
- NCT01567436
- Testing
- Shang Ring
- Where
- 2 sites in Kenya, Zambia
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- FHI 360
Circumcision
Bipolar Electrosurgery Versus Thermocautery in Circumcision With Safe Anesthetic Techniques
Background: Circumcision is the most commonly performed surgical procedure done among the pediatric age group worldwide and is considered to be one of the oldest operations done.
- Trial name
- NCT05590052
- Testing
- Bipolar Electrosurgery, Thermocautery
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Damanhour Teaching Hospital
Disease Due to Gram-positive Bacteria
A Trial Assessing Efficacy of Various Antimicrobial Techniques for Reducing Bacterial Load
There is a potential of bacterial overgrowth under the foreskin in the sub-preputial space, therefore we would like to investigate possible techniques to reduce this potential.
- Trial name
- RMC-11 (NCT02391077)
- Testing
- Povidone-Iodine, Antibiotic topical cream, Chlorhexidine 1%
- Where
- Rwanda
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Circumcision, Male
Examination of Short and Long Term Complications of Thermocautery, Plastic Clamping and Surgical Circumcision Techniques
Since circumcision is a significant workload for surgeons working at the rural state hospitals in Turkey, the use of circumcision techniques that are easy to implement and have low complications is becoming widespread.
- Trial name
- NCT03136224
- Testing
- Thermocautery, Plastic Clamping, Surgical Circumcision
- Volunteers
- 2,062 people, healthy volunteers welcome
- Sponsor
- Kocatepe University
Pain Catastrophizing
Maternal Pain Catastrophizing Score is Related With Children's Postoperative Circumcision Pain
The aim of this study was to evaluate the relation of maternal pain catastrophizing score with child's who underwent circumcision postoperative pain.
- Trial name
- NCT05950126
- Testing
- pain catastrophizing scala
- Where
- Turkey (Türkiye)
- Volunteers
- 197 people
- Sponsor
- Sevda Akdeniz,MD
Circumcision, Lower Abdominal Surgery
Comparison of Caudal Block and Erector Spinae Block for Postoperative Analgesia
Caudal block (CB), a regional anesthesia technique, is the most commonly used neuraxial block method for postoperative pain control in sub-umbilical surgeries in children.
- Trial name
- NCT05284734
- Testing
- Regional anesthesia intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
HIV Infection
The Use of Peer Referral Incentives to Increase Demand for Voluntary Medical Male Circumcision in Zambia
The Centre for Infectious Disease Research in Zambia (CIDRZ) and researchers from the University of North Carolina at Chapel Hill (UNC) have partnered to pilot an peer-referral incentive program to increase voluntary medical male…
- Trial name
- NCT02012816
- Testing
- Peer-referral incentive program to increase VMMC uptake
- Where
- Zambia
- Volunteers
- 725 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Prepuce; Accessory
Outcomes Of The Different Techniques Of Male Circumcision
Aim of work: The aim of study is to comprehensively evaluate and compare the efficacy, safety, clinical outcomes, cosmetic appearance and complication rates associated with different technique of circumcisions.
- Trial name
- NCT06766838
- Testing
- 1. Conventional dissection technique (group A) :, 2. Bone cutting forceps technique (Group B), 3. Electro-cauterization (bipolar) assisted circumcision (Group C)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Human Immunodeficiency Virus
Use of the Shang Ring Circumcision Device in Boys Below 18 Years Old in Kenya
A proof of concept study to evaluate the feasibility of using the Shang Ring, a novel male circumcision device across all childhood age groups namely infants (under 1), 1-5 age group, 6-12 age group and the 13-17 age group.
- Trial name
- NCT01891409
- Testing
- Male circumcision using the Shang Ring device
- Where
- Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- EngenderHealth
Anxiety, Fear
Children's Anxiety and Fear Before Circumcision
This study was planned as a randomized controlled trial to investigate the effect of ready-made picture template coloring activity on children's anxiety and fear before circumcision.
- Trial name
- NCT07203820
- Testing
- Ready-Made Picture Template Painting Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University
Analgesia, Pain, Postoperative
Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision
Prospective, randomized, case-controlled trial study. Observation post-operatively: Aims: This study aimed to compare the effectiveness of the caudal block CB with other methods of postoperative pain release.
- Conditions
- Analgesia, Pain, Postoperative, Pain, Acute
- Trial name
- paincontrol (NCT06086106)
- Testing
- caudal block, Dorsal Penile Nerve Block DPNB, Systemic opioids
- Where
- Bahrain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Circumcision
Parents' Knowledge and Perception of Benefits and Risks Regarding Neonatal Circumcision
The American Academy of Pediatrics changed their stance on circumcision to "health benefits of newborn male circumcision outweigh the risks and that the procedure's benefits justify access to this procedure for families who…
- Trial name
- NCT01909609
- Testing
- AAP Documents, Parent Survival Guide
- Where
- United States
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Human Immunodeficiency Virus
Simplifying the Shang Ring Technique for Circumcision of Men and Boys
This is a research study in Kenya that will examine the outcomes of participants aged 10-15 and 16 and older; and provider acceptability of the Shang Ring technique for male circumcision that would simplify use.
- Trial name
- NCT02390310
- Testing
- Shang Ring, injectable anesthesia (lidocaine 1%), topical anesthesia (lidocaine 2.5%, prilocaine 2.5% cream)
- Where
- 2 sites in Kenya
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- EngenderHealth