Clinical trials: Citrate
Female Infertility
Effectiveness of Low Dose Gonadotropin Stimulation Protocol Vs High Dose Gonadotropin Protocol in Poor Responders
In the present study we examined the effect of addition of CC to a low dose gonadotropin (150 IU/day) / GnRH antagonist protocol in comparison to a high gonadotropin dose (300 IU/day) regiment (short protocol) in women with poor…
- Trial name
- NCT06778733
- Testing
- Clomiphane citrate, recombinant human Follicle-Stimulating Hormone (r-FSH-alfa)
- Where
- 2 sites in Greece
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Athens
Polycystic Ovary
Clomiphene Citrate Stair-Step Protocol
A RCT will be conducted to compare the traditional clomiphene citrate regimens for ovulation induction with the stair-step protocol.
- Trial name
- NCT03178500
- Testing
- Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Exercise-Induced Fatigue, Athletic Performance
The Effect of Individual Sodium Citrate Consumption on Repeated Sprint Performance in Female Soccer Players
The aim of this research is to determine whether sodium citrate supplementation, taken at the best individual time, would improve repeated sprint performance in professional female soccer players.
- Conditions
- Exercise-Induced Fatigue, Athletic Performance, Soccer
- Trial name
- ITSCORE-F (NCT07737327)
- Testing
- Sodium Citrate Oral Product
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Metabolic Syndrome, Dialysis; Complications
Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients
This prospective, multicenter, cross-sectional, repeated-measures comparative study compared functional and biochemical response profiles to exercise between 2 groups of chronically ill patients (chronic renal failure dialysis…
- Trial name
- KREBSome-IRC (NCT06360302)
- Testing
- Exercise test, Blood sample, Impedancemetry
- Where
- 2 sites in France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cirrhosis, Hepatic Encephalopathy
Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System
The purpose of the current study is to look into the pathogenesis of a severe medical condition causing acute episodes on the central nervous system as seen in majority of patients with liver cirrhosis.
- Trial name
- NCT00424957
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Calcium Citrate Absorption, Calcium Carbonate Absorption
Comparison of the Absorption of Calcium Citrate and Calcium Carbonate in Patients With an RYGB, LSG, and OAGB
The precise impact of calcium absorption in relation to RYGB, SG, and OAGB remains under-researched in terms of statistical power and the diversity of BMS procedures considered.
- Trial name
- CALCOR-RSO (NCT06042985)
- Testing
- The absorption effect between calcium citrate and calcium carbonate
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Biological Availability
Pharmacokinetics of Fentanyl Following Intravenous and Oral Routes of Administration in Healthy Volunteers
The purpose of the study is to compare the pharmacokinetics of fentanyl following i.v. and oral administration in healthy volunteers, and to assess the bioavailability of fentanyl following oral administration.
- Trial name
- NCT00714558
- Testing
- Fentanyl citrate; Naltrexone; Naloxone
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Alza Corporation, DE, USA
Healthy
A Study of Butamirate Citrate Syrup Versus (vs) Sinecod Syrup (Vanilla) in Adult Healthy Study Volunteers
The purpose of this study is to evaluate bioequivalence with respect to rate and extent of absorption of 2-phenylbuturic acid of the novel medication butamirate citrate syrup 1.5 milligrams per milliliter (mg/mL), and the…
- Trial name
- NCT05182047
- Testing
- Butamirate citrate, Sinecod
- Where
- Russia
- Volunteers
- healthy volunteers welcome
- Sponsor
- McNeil AB
Dental Plaque
Evaluation of the Effect of Zinc Citrate Trihydrate Toothpaste on the Oral Plaque Microbiome
This study is of a double-blind, randomised, parallel group study. Subjects will be enrolled onto the study according to the inclusion/exclusion criteria.
- Trial name
- NCT06358742
- Testing
- ZCT toothpaste, Control toothpaste
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Catheter Blockage
UROtainer for Bladder Catheter Maintenance, Infection Prevention and Quality of Life
The purpose of the current study is to investigate whether catheter flushing with Uro-Tainer® with citric acid and Uro-Tainer® Polihexanide can: Reduce catheter changes due to incrustation and blockage.
- Trial name
- UROBIQ (NCT05775614)
- Testing
- UroTainer®, Saline
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Dysmenorrhea
Viagra in the Treatment of Primary Dysmenorrhea
The primary hypothesis is that a 100mg single dose of sildenafil citrate (Viagra) will have a higher improvement rate when compared to placebo in the treatment of moderate to severe primary dysmenorrhea.
- Trial name
- NCT00123162
- Testing
- Sildenafil Citrate
- Where
- Croatia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
End Stage Renal Disease
Pharmacokinetics of Triferic (Ferric Pyrophosphate Citrate) Administered Intravenously to Healthy Adult Volunteers
This is a Phase 1, open-label, three-period sequential dosing study being conducted to determine the pharmacokinetics of Triferic iron administered intravenously (IV) to healthy adults.
- Trial name
- RMFPC-12 (NCT02636049)
- Testing
- Triferic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rockwell Medical Technologies, Inc.
Chronic Cough
Cough in Eastern and Central Finland
Comparison of citric acid and mannitol cough provocation tests among subjects with chronic cough and healthy volunteers.
- Trial name
- NCT03639727
- Testing
- Citric acid aerosol bronchial challenge, Mannitol aerosol bronchial challenge
- Where
- Finland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Obesity, Overweight
The Effect of Citric Flavonoid on Endothelial Function
This randomized, double-blind, placebo-controlled, parallel study aims to determine the 6-week and acute effects of daily administration of a citrus flavonoid on cardiovascular and intestinal health as assessed by investigation…
- Trial name
- NCT02228291
- Testing
- Capsule containing citrus flavonoid
- Where
- Netherlands
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Polycystic Ovarian Syndrome
The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)
As both medications i.e. CC and letrozole have been shown to be effective in inducing ovulation in PCOS patients, this study was performed in order to evaluate which regime (whether CC or letrozole) is the best to be used as the…
- Trial name
- NCT01577017
- Testing
- Letrozole
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nik Hazlina
Healthy
Drug-Drug Interaction of Clomipramine HCl and Sildenafil Citrate in Healthy Males
The purpose of this study is to evaluate the safety and pharmacokinetics/pharmacodynamics of co-administration of Clomipramine HCl 15mg and Sildenafil citrate 100mg compared to the effects after single oral administration in…
- Trial name
- NCT02028598
- Testing
- Treatment 1, Treatment 2, Treatment 3
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CTC Bio, Inc.
Polycystic Ovary Syndrome, Anovulation
The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women
The purpose of our study was to conduct a placebo controlled, double-blind randomized trial in chronic oligoovulatory or anovulatory , hyperandrogenic, infertility patients comparing the effects of adjuvant metformin plus…
- Conditions
- Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility
- Trial name
- NCT00413179
- Testing
- Metformin, Clomiphene citrate
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Infertility, Anovulation
Efficacy Study of the OV-Watch™ Personal Fertility Monitor for Women Using Clomiphene Citrate.
The purpose of this study is to evaluate the effectiveness of the OV-Watch to predict ovulation while women are taking clomiphene citrate.
- Conditions
- Infertility, Anovulation, Polycystic Ovary Syndrome
- Trial name
- NCT00239603
- Testing
- OV-Watch
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University
Infertility
Cost Effectiveness Analysis for Induction of Ovulation in the Polycystic Ovary Syndrome by Letrozole Versus Clomiphene Citrate
To evaluate cost effectiveness of Letrozole versus clomiphene citrate (CC) in induction of ovulation in patients with polycystic ovary syndrome.
- Trial name
- NCT04361175
- Testing
- Letrozole, Clomiphine Citrate
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obesity, Diabetes
Calcium, Protein and Gut Hormones
Gut hormones have therapeutic potential in the prevention and treatment obesity and type 2 diabetes (T2D). Milk protein and calcium can each potentiate gut hormones following meal ingestion in humans.
- Trial name
- NCT03232034
- Testing
- Calcium Citrate, Milk Mineral Supplement, Whey Protein Hydrolysate
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bath