Clinical trials: Class I Obesity
Overweight, Obesity
Effect of Chili Pepper Extract on Weight and Fat Loss and Metabolism Increase
The purpose of this study is to test the safety and effectiveness of a purified extract of CH-19 Sweet, containing capsinoids.
- Trial name
- NCT00825838
- Testing
- Chronic consumption of chili pepper extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ajinomoto USA, INC.
Periodontitis, Obesity
Effect of Periodontal Debridement on Leptin Levels in Obese
The main purpose of the study is to quantify of Leptin hormone in patients with normal weight, class I obesity, class II obesity and periodontitis, before and after scaling and root planning (SRP) and correlate the Body mass…
- Trial name
- NCT04417478
- Testing
- Scaling and root planning
- Where
- Chile
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Andres Bello
Hypercholesterolemia, Overweight and Obesity
Metabolic Effect of an Innovative Chitosan Formulation
Chitosan is a natural polysaccharide of β-1,4-linked glucosamine residues deriving from chitin, a dietary fiber primarily obtained from fungal cell walls and the exoskeletons of various crustaceans (e.g.
- Trial name
- CHITOCHOL (NCT05188430)
- Testing
- Medical Device (Kaptufat®)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Overweight , Obesity, Class I Obesity
Dietary Guidelines for Americans-Ultra Processed Study
The purpose of this research is to test how processing food can affect how one's body responds to it.
- Trial name
- DGA-UP (NCT07252037)
- Testing
- Low-processed DGA Diet, Ultra-processed DGA Diet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Body Weights and Measures, Body Weight in the Overweight and Obese Class - I Population
Machine Learning and 3D Image-Based Modeling for Real-Time Body Weight and Body Composition Estimation During Emergency Medical Care. Study 1
The goal of this observational study is to train and validate an AI-driven 3D camera system to estimate total body weight, ideal body weight and lean body weight in male and female adult volunteers of all ages.
- Trial name
- NCT06646120
- Volunteers
- healthy volunteers welcome
- Sponsor
- Florida Atlantic University
Obesity
Safety Study of the Inhibition of Agouti-related Protein (AgRP) for the Management of Obesity and Weight Loss
Multiple pathways including peripheral and central hormones and neurotransmitters are involved in the regulation of food intake and body weight. One of the most studied pathways involves the melanocortin receptor.
- Trial name
- NCT00779519
- Testing
- TTP435
- Where
- 12 sites in United States, Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- vTv Therapeutics
Class I Obesity, Pediatric Obesity
Virtual Housecalls: Redesigning Pediatric Primary Care Adolescent Obesity Treatment
This pragmatic randomized clinical trial tests a novel intensive health behavior and lifestyle intervention, conducted via telehealth, to treat class I adolescent obesity in pediatric primary care.
- Trial name
- VHC (NCT07246603)
- Testing
- Virtual Housecalls
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Obesity
Exercise Response on Dose Curve Among Class I Obese Young Adult Population
The study is aimed to determine impact of dynamic resistance exercise training on Body Fat percentage of class-I Obese population and to quantify the dose of exercise program using a probit regression curve
- Trial name
- NCT04382742
- Testing
- Dynamic Resistance Exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Assess the Effect of an IR Reflexotherapy on Overweight and Class I Obese People
Interest in the Medium Term of an Infrared Reflexotherapy on Overweight or Class I Obese People
The study aim is to Assess the Effect of an IR Reflexotherapy on Overweight and Class I Obese People.
- Trial name
- REFLEX-IR (NCT02000037)
- Testing
- IR Reflexotherapy, Dietary care
- Where
- France
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Class I/II Obesity
Translational Health Research Into Vascular and Neurocognitive Effects of Weight Loss
The goal of this clinical trial is to learn about the nature of brain abnormalities associated with excess body fat in healthy adults aged 35-55.
- Trial name
- THRIVE (NCT07592546)
- Testing
- semaglutide
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Alain Dagher
Class I Obesity
Trial of Innovative Fat-loss Focused Approaches in Patients With Class I Obesity: a Comparative Study
This single-center randomized comparative study is designed to compare the effectiveness of tirzepatide and transcutaneous low-frequency auricular vagus nerve stimulation in adults with class I obesity and without chronic…
- Trial name
- TIFFANY (NCT07866183)
- Testing
- Tirzepatide, Transcutaneous auricular vagus nerve stimulation
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Amino Acid, Body Weight Changes
A Specialized Amino Acid Mixture on Body Composition and Skin State in Overweight and Obese Class I Postmenopausal Women
The use of dietary amino acids has been explored for therapeutic and safety intervention of obesity and obesity-induced dysfunction.
- Conditions
- Amino Acid, Body Weight Changes, Skin Manifestations, Obesity
- Trial name
- NCT04701463
- Testing
- L-glutamine, L-arginine and calcium beta-hydroxy-beta-methylbutyrate
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Insulin Sensitivity, Obesity
The Metabolic Effects of Cynara Supplementation in Overweight and Obese Class I Subjects With Newly Detected Impaired Fasting Glycaemia.
Impaired fasting glucose (IFG) is a condition that precedes diabetes and increases the risk of developing it. Studies support the hypoglycemic effect of Cynara cardunculus (Cs) extracts due to the content of chlorogenic acid…
- Conditions
- Insulin Sensitivity, Obesity, Overweight
- Trial name
- NCT04616404
- Testing
- 500 mg of artichoke extract
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Body Weights and Measures, Body Weight in the Overweight and Obese Class - I Population
Machine Learning and 3D Image-Based Modeling for Real-Time Body Weight and Body Composition Estimation During Emergency Medical Care: Study 2
The goal of this prospective crossover simulation study is to evaluate the accuracy and usability of a 3D camera weight estimation system during simulated emergency care in adult simulated patients, when used by emergency…
- Conditions
- Body Weights and Measures, Body Weight in the Overweight and Obese Class - I Population, Weight Estimation, Emergency Drug Dosing
- Trial name
- NCT06646133
- Testing
- 3D camera weight estimate, Standard methods of weight estimation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Florida Atlantic University
Overweight and Obesity
Safety and Feasibility Assessment of the Bio-electrical One Day Capsule System in Overweight and Class I Obese Participants
The study represents the first effort to prospectively investigate the Melcap's bio-electrical ingestible ODC system in human. The study goal is to evaluate the safety and feasibility of GES treatment in stomach and in the small…
- Trial name
- NCT03734081
- Testing
- ODC system (type 1 capsule), ODC system (type 2 capsule)
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Melcap Systems Ltd.