Clinical trials: Clear Aligner Therapy, open to volunteers
Malocclusion
FM Technique in Orthodontic Clear Aligner Therapy: A Single-Arm Clinical Study
This trial tests whether a new method (FM) for moving back teeth can shorten clear-aligner treatment. All participants use FM, which moves the canine and first molar back together instead of one tooth at a time like the standard…
- Trial name
- NCT07896369
- Testing
- Clear aligners with FM (Fluid Move) design
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Angle Class I Maloclussion, Dental Crowding
Orthodontic Treatment Outcomes of Self Ligating System Compared to Clear Aligner System
This study is a multi-center, prospective, parallel-group randomized controlled trial designed to compare the orthodontic treatment outcomes of a passive self-ligating bracket system (Damon Ultima) versus a clear aligner system.
- Trial name
- NCT07638397
- Testing
- self ligating bracket, Clear aligner
- Where
- Iraq
- Volunteers
- 42 people
- Sponsor
- University of Baghdad
Dental Crowding,Interproximal Enamel Reduction, Malocclusion, Angle's Class
Accuracy and Periodontal Outcomes of Three Interproximal Enamel Reduction Techniques During Clear Aligner Therapy
This randomized controlled clinical trial will compare three commonly used interproximal enamel reduction (IPR) techniques during clear aligner therapy in adult patients.
- Conditions
- Dental Crowding,Interproximal Enamel Reduction, Malocclusion, Angle's Class, Periodontal Diseases
- Trial name
- NCT07377825
- Testing
- Manual Arm, Motor Driven Arm, Abrasive Arm
- Where
- Saudi Arabia
- Volunteers
- 75 people
- Sponsor
- Riyadh Elm University
Malocclusion
A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.
This is a three-armed, multicenter clinical study evaluating the SureSmile clear aligner medical device. The primary objective is to confirm the safety and assess the accuracy of different tooth movements.
- Trial name
- NCT07290790
- Testing
- SureSmile® Clear Aligners
- Where
- 6 sites in United States, Spain and 1 more
- Volunteers
- 90 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Orthodontic Treatment, Saliva
Salivary Flow, pH, and Buffering Capacity in Fixed and Clear Aligner Orthodontic Treatment
Study Design: A randomized controlled trial with two parallel arms and an allocation ratio of 1:1. Setting: The study will be conducted in the orthodontic department of Riyadh Elm University hospitals in Riyadh City, Saudi…
- Trial name
- NCT07397871
- Testing
- Fixed orthodontic appliances, Clear Aligner Treatment
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Riyadh Elm University
Masseter Muscle Activity, Anterior Temporalis Muscle Activity
Orthodontic Clear Aligners Vs Conventional Fixed Appliance's Impact on Muscular Activities Among Adults Using SEMG (Surface Electromyography)
This clinical trial goal is to evaluate the difference in masticatory activities in adult patients treated with clear aligners compared to conventional fixed appliances treatment.
- Trial name
- NCT06699290
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Riyadh Elm University
Open Bite
Investigate the Effectiveness of 3D-printed Shape Memory Aligners in the Treatment of Anterior Open Bite
The goal of this randomised clinical trial study is to investigate 3D-printed shape memory aligners in the treatment of anterior dental open bite adult patients. The main questions it aims to answer are: 1.
- Trial name
- NCT07420777
- Testing
- SMA with attachment, SMA without attachments, CA with attachment
- Where
- Iraq
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Kufa University
Clear Aligner Orthodontic Treatment, Composite Attachment
Tooth Discoloration and Chairside Handling Time (Bonding-Debonding) in Flowable Versus Packable Composites for Clear Aligner Bonded Attachments: A Randomized Clinical Trial
This randomized split-mouth clinical trial aims to compare two different composite materials used for bonding attachments in clear aligner orthodontic therapy.
- Conditions
- Clear Aligner Orthodontic Treatment, Composite Attachment, Color Stability of Enamel
- Trial name
- NCT07234149
- Testing
- flowable nanohybrid Composite Resin, Packable Microhybrid Composite Resin
- Where
- 2 sites in Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani
Malocclusion
Accuracy of Dental Movements Using Clear Aligners Treatment: a Single-center Prospective Observational Study
The aim of the present prospective observational study is to evaluate the accuracy of dental movements in the three planes of space, assessing the correspondence between the virtual planned movements and the clinical outcomes…
- Trial name
- NCT06561945
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Clear Aligner Therapy, Aligner Attachment Wear
Clinical Evaluation of Customized Attachment Composites in Clear Aligner Therapy
This prospective observational clinical study aims to evaluate the three-dimensional surface wear and clinical survival of orthodontic attachments fabricated with customized composite materials used in clear aligner therapy.
- Trial name
- NCT07261735
- Testing
- GC G-ænial A'Chord Universal Composite, Spectra ST HV (High Viscosity), Spectra ST LV (Low Viscosity)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Rotation of Tooth
A Novel Attachment Design for Tooth Rotation With Clear Aligner Therapy
Clear aligners are thin, transparent plastic trays that straighten teeth gradually and are a popular, more discreet alternative to traditional braces.
- Trial name
- NCT07881146
- Testing
- novel attachment configuration
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Boston University
Skeletal Class III Malocclusion
Skeletal and Dentoalveolar Effects of Functional Clear Aligner Therapy in Growing Patient With Skeletal Class III Malocclusion
The purpose of this study is to evaluate the skeletal, dentoalveolar \& soft tissue effects of functional clear aligner therapy in growing patient with Skeletal class III malocclusion.
- Trial name
- NCT07703007
- Testing
- Functional Clear Aligner
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Mansoura University
Distalization, Class II Malocclusion
Comparison of Distalization of Maxillary First and Second Molars Between a Miniscrew Implant Supported Device and Clear Aligners.
The goal of this randomized clinical trial is to compare distalization of maxillary first and second molars achieved with a device supported with mini screw implants in the palate (Advanced Molar Distalization Appliance, AMDA®)…
- Conditions
- Distalization, Class II Malocclusion, Aligner Therapy, Distalization by Miniscrews
- Trial name
- NCT07040176
- Testing
- Upper molar distalization
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki