Clinical trials: Cleft Lip Palate
Cleft Lip and Palate
Alt-RAMEC Expansion and Protraction by EDO in Cleft Lip and Palate Patient
Evaluate the treatment outcome of Alternate Rapid Maxillary Expansion and Constriction Alt-RAMEC protocol on patients with cleft lip and palate, using a differential opening expander and face mask which will be measured and…
- Trial name
- NCT04970095
- Testing
- Maxillary Expander with Differential Opening (EDO), Petit Face Mask
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Toothbrushing, Gingivitis
Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery
The study is a randomized clinical trial to compare the effectiveness of a dual light ultrasonic toothbrush on periodontal health in orthodontic patients undergoing surgery.
- Conditions
- Toothbrushing, Gingivitis, Cleft Lip and Palate
- Trial name
- NCT06122805
- Testing
- Toothbrush
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Cleft Lip, Cleft Palate
Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)
The Allied Cleft \& Craniofacial Quality-Improvement and Research Network (ACCQUIREnet) is a group of multidisciplinary cleft teams that have implemented a system for prospective collection of outcomes data, based on the ICHOM…
- Conditions
- Cleft Lip, Cleft Palate, Cleft Lip and Palate
- Trial name
- ACCQUIREnet (NCT02702869)
- Testing
- cleft lip repair, cleft palate repair, oronasal fistula repair
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,000 people
- Sponsor
- Duke University
Maxillary Deficiency, Cleft Lip and Palate
Evaluation of Maxillary Expansion Using Clear Aligners' Therapy in Patients With Cleft Lip and Palate at the Mixed Dentition Stage
The goal of this clinical trial is to learn if the aligners can expand upper dental arch in patients with cleft lip and palate at age of 6-8 years old to correct their collapsid archs.
- Trial name
- Pilot (NCT06994754)
- Testing
- clear aligners
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Cleft Lip and Palate
Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing
Despite significant progress made in identification on numerous genes and gene pathways critical for craniofacial development, several approaches, ie mutation screening of specific candidates, association studies and even…
- Trial name
- GENEPIC (NCT03065686)
- Testing
- identification of genetic factors
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cleft Lip and Palate
the Relationship Between Cleft Lip and / or Palate (Different Types) and ABO Blood Groups.
Direct benefit of the research to assess the relationship between cleft lip and / or palate (different types) and ABO blood groups.
- Trial name
- NCT03217890
- Volunteers
- 376 people
- Sponsor
- Cairo University
Cleft Lip and Palate, Unilateral Cleft Lip
Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate
Orofacial clefts are the second most common birth deformity and vary in etiology and phenotype, e.g. isolated cleft palate, cleft lip or cleft lip palate.
- Trial name
- NCT05081258
- Testing
- passive Alveolar Molding, Nasoalveolar Molding
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
Cleft Lip and Palate, Periodontal Pocket
Periodontal Changes Following Mid Maxillary Distraction
To evaluate the health status of the periodontium and dentition at the distraction osteogenesis site in CLP subjects using mid maxillary distraction (MMD).
- Conditions
- Cleft Lip and Palate, Periodontal Pocket, Attachment Loss, Periodontal
- Trial name
- NCT03686761
- Testing
- A Involvement with the osteotomy site of the surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
Cleft Lip and Cleft Palate
Detection of Single Nucleotide Polymorphism (SNP) Rs2235371 of IRF6 Gene in Egyptian Patients with Non-Syndromic Cleft Lip and Palate
The aim of this work is to study the relation between SNP rs2235371 of IRF 6 gene and Non-Syndromic Cleft Lip and Palate in Egyptian Patients in a prospective study
- Trial name
- NCT06730880
- Testing
- PCR
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Head and Neck Neoplasm, Cleft Palate
Characteristics of a Maxillofacial Prosthesis Consultation Within Assistance Publique - Hopitaux de Paris
Patients treated with Maxillofacial Prosthesis have loss of maxillary and/or mandibular substances. Few data are available on quality of life of these patients and its association with some of their socio-demographic, medical and…
- Conditions
- Head and Neck Neoplasm, Cleft Palate, Cleft Lip
- Trial name
- PEC-PMF (NCT04277273)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cleft Lip
Osteogenesis and Dental Eruption Through Electrical Stimuli
The closure of the alveolar cleft as part of cleft lip and palate deformities is a procedure that, to this date, still demands great efforts from plastic surgeons.
- Trial name
- NCT00975208
- Volunteers
- 9 people
- Sponsor
- University of Guadalajara
Cleft Lip and Palate
The Effect of a Newly Designed Presurgical Orthopedic Appliance
A randomized clinical trial to compare the effectiveness of newly designed active type of presurgical orthopedic appliances on maxillary arch dimensions in infants with bilateral cleft lip and palate.
- Trial name
- NCT05535530
- Testing
- Active PSIO
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Blepharocheilodontic Syndrome
CDH1-associated Blepharocheilodontic Syndrome Registry
The aim of the CDH1-associated Blepharocheilodontic Syndrome (BCDS) registry is to better characterize the clinical features of this condition and exploring whether CDH1 variants linked to BCDS may also increase cancer risk.
- Trial name
- NCT07133464
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Cleft Lip, Cleft Palate
Oral Cleft Prevention Program
The purpose of this study is to asses if taking 4 mg of folic acid per day at preconception and during the first three months of pregnancy decreases the risk of having a child with cleft lip and palate compared to 0.4 mg folic…
- Trial name
- NCT00397917
- Testing
- Folic acid: 4 mg versus 0.4 mg per day
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- University of Iowa
Cleft Lip, Cleft Palate
Characterization of Cleft Lip and Palate Conditions in Guatemala
The purpose of this study is to compare types of and risk factors for cleft lip and palate in a Guatemalan population to a United States population.
- Conditions
- Cleft Lip, Cleft Palate, Cleft Lip and Palate
- Trial name
- NCT04725370
- Testing
- NA - survey instrument
- Where
- United States
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia