Clinical trials: Clinical
Disorders of Consciousness
Resting State fMRI in Disorders of Consciousness
Disorders of consciousness (DoC) remain a major clinical challenge in which high rates of misdiagnosis and difficult prognostication stem from limitations in the ability to access the disordered physiological processes mechanisms…
- Trial name
- NCT05463029
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Acne Vulgaris
"A Comparative Clinical Evaluation of the Efficacy of Topical Adapalene, Benzoyl Peroxide Gel, Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, and Their Fixed Combination in Mild to Moderate Acne Vulgaris Patients."
The study aims to conduct a comparative clinical evaluation of the effectiveness of a fixed topical combination of adapalene with benzoyl peroxide in the form of a gel, a fixed combination of Lactobacillus rhamnosus…
- Trial name
- NCT05855629
- Testing
- Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, Topical Adapalene, Benzoyl Peroxide Gel
- Where
- Ukraine
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Treatment and Diagnostic Center of Private Enterprise "Asklepiy"
Cardiopulmonary Exercise Test Interpretation
AI-Assisted Anaerobic Threshold Interpretation in Cardiopulmonary Exercise Testing
This prospective randomized two-period crossover reader study will evaluate whether assistance from a frozen artificial intelligence model improves physicians' interpretation of the anaerobic threshold (AT) in cardiopulmonary…
- Trial name
- PACE-Reader (NCT07833137)
- Testing
- AI-Assisted Anaerobic Threshold Interpretation, Unassisted Cardiopulmonary Exercise Test Interpretation
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Optical Biometry of the Human Eye, General Analysis of the Anterior Chamber of the Human Eye
Clinical Trial ES 900 - 2019
The primary objective of this clinical trial is to assess the clinical performance of the investigational device. To that end, the Limits of Agreement with respect to comparator devices are analyzed.
- Trial name
- NCT04112472
- Testing
- EYESTAR 900
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Haag-Streit AG
Clinical Pharmacology
Study to Compare the Effect of the Formulations (Orally Disintegrating Tablet and Film-coated Tablet) on the Bioequivalence of Drug Rivaroxaban (Xarelto) at Dose of 15 mg in Japanese Healthy Male Adult Subjects
Researchers in this study wanted to compare the effect of the formulation (orally disintegrating tablet and film-coated tablet) on the bioequivalence of drug Rivaroxaban (brand name: Xarelto) at dose of 15 mg in Japanese healthy…
- Trial name
- NCT04511637
- Testing
- Rivaroxaban (BAY 59-7939, Xarelto) in ODT form, Rivaroxaban (BAY 59-7939, Xarelto) in film-coated form
- Where
- 3 sites in Japan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bayer
Periodontal Diseases
Slow-release Locally Administered 0.02% Hypochlorite Formulation
Aim: The presence of bacterial plaque is associated with the development of periodontal inflammation. The aim of this single-blind randomized clinical study was to prospectively evaluate the efficacy of two different agents in a…
- Trial name
- NCT05846139
- Testing
- PerioTabs® brushing solution, Chlorhexidine 0.12 %
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tuscan Dental Institute
Osteopenia, Osteopenia of the Elderly
A Clinical Trial Investigating the Effect of Salmon Bone Meal on Bone Mass Among Osteopenic Women
The purpose of this study is to evaluate the efficacy of salmon bone meal in preventing bone loss among perimenopausal women with reduced bone mass density.
- Trial name
- NCT05066477
- Testing
- CalGo
- Where
- 3 sites in Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA
Tinea Pedis
Topical Tolnaftate Stick for Tinea Pedis: An Open-Label Interventional Study
This study is designed to evaluate the safety and effectiveness of multiple 1% tolnaftate formulations delivered through novel stick-based vehicles in individuals with tinea pedis (athlete's foot).
- Trial name
- NCT07245667
- Testing
- 1% Tolnaftate Stick Formula A, 1% Tolnaftate Stick Formula B, 1% Tolnaftate Stick Formula C
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Propedix, Inc.
Mandibular Deficiency
Accuracy of Implant Placement for Patients With Mandibular Reconstruction Using Dynamic Navigation and Static Guides
To evaluate and compare the accuracy of implant placement using dynamic navigation technique versus static template technique in patients with bone tissue flap reconstruction of mandibular defects, thus further guiding the…
- Trial name
- NCT06250907
- Testing
- The guidance of dynamic navigation, The guidance of static template
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Healthy, no Evidence of Disease
Studying Different Formulations of SR13668 in Healthy Volunteers
This randomized early phase I trial is studying different formulations of SR13668 in healthy volunteers. Giving SR13668 may help doctors learn more about how SR13668 is used by the body.
- Trial name
- NCT00896207
- Testing
- Akt inhibitor SR13668
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Intradialytic Hypotension
The Clinical Study of Improving the Thirst and Hypotension of Hemodialysis Patients
This clinical study is to observe the improvement of MHD (maintenance hemodialysis) patients, quality of life，after applying therapy combining Auriculotherapy and Shengmai capsule.
- Trial name
- NCT02583802
- Testing
- Ear pills, Shengmai capsule
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beijing University of Chinese Medicine
COVID 19
Safe Return to Regular Clinical Operation After COVID-19 Pandemic
. Coronavirus (SARS-CoV2) appeared first in China late 2019 and caused an acute respiratory disease referred to as Coronavirus disease 2019 (COVID-19).
- Trial name
- NCT04377802
- Testing
- molecular testing for virus RNA using RT-PCR
- Where
- Saudi Arabia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- King Fahad Specialist Hospital Dammam
Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis)
Study of Single and Multiple Ascending Doses of CM551 in Healthy Participants
This is a randomized, double-blind, placebo-parallel controlled phase I study to evaluate the safety and tolerability of single and multiple doses of CM551 in healthy participants
- Trial name
- NCT07900945
- Testing
- CM551
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Keymed Biosciences Co.Ltd
Cognitive Therapy, Depression, Postpartum
RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood
The purpose of this study is to investigate the efficacy of an evidence-based smartphone application (app) for the management of mood compared to treatment as usual alone among 135 women who have been discharged post-delivery…
- Conditions
- Cognitive Therapy, Depression, Postpartum, Mental Health, Depression
- Trial name
- NCT03646539
- Testing
- Use of smartphone application (app), Treatment as usual
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Stanford University
Respiratory Conditions Due to Unspecified External Agent
Anti-pollution Effects of AP Green Tea Extracts
The objective of this clinical trial is to evaluate the anti-pollution effects of AP green tea extracts in subjects with discomforts related to the respiratory system by prolonged exposure to particulate matter in air pollution
- Trial name
- NCT04340375
- Testing
- AP green tea extracts
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
Gut Microbiota Modulation
The Role of Probiotic LH76 in Human Gut Health
This study aims to evaluate the safety and efficacy of the probiotic LH76 as a dietary supplement in healthy adults. The research will assess its effects on gut microbiota composition, intestinal health, and immune function…
- Trial name
- NCT06875375
- Testing
- probiotic LH76
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Healthy Participants, IBD (Inflammatory Bowel Disease)
A Phase I Study of HW201877 in Healthy Subjects
This is a Phase I, randomized, double-blind, placebo-controlled study to assess the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and food effect (FE) of HW201877 in healthy subjects following (1) a single…
- Trial name
- NCT07373457
- Testing
- HW201877 capsules
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Wuhan Humanwell Innovative Drug Research and Development Center Limited Company
Stress Urinary Incontinence
Value of Urodynamics Prior to Stress Incontinence Surgery
To test the value of preoperatively performed urodynamics with regard to outcome of surgery for stress urinary incontinence (SUI) and to examine whether not performing urodynamics preoperatively is more cost effective than…
- Trial name
- VUSIS (NCT00509730)
- Testing
- Urodynamics
- Where
- Netherlands
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Morphology
Diagnostic Agreement Between Clinical Assessment and CBCT Palatal Angle for Palatal Arch Shape
Standardized intraoral photographs corresponding to each CBCT scan will be evaluated by two calibrated examiners. Palatal arch shape will be visually classified into one of three categories: high arched palate, normal palate, or…
- Trial name
- NCT07363200
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Amyotrophic Lateral Sclerosis
Clinical Research in ALS Study
CRiALS is an umbrella protocol through which people are recruited to participate in a range of research studies being conducted by the ALS Research Collaboration (ARC).
- Trial name
- CRiALS (NCT00136500)
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Miami
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