Clinical trials: Clinical
Seasonal Influenza
Clinical Trial to Evaluate the Safety and Immunogenicity of Quadrivalent Influenza Vaccine (7.5μg/0.25ml)
The purpose of this study is to evaluate the safety and immunogenicity of quadrivalent influenza vaccine in healthy children aged 6-35 months.
- Trial name
- NCT03859141
- Testing
- Quadrivalent influenza vaccine, Trivalent influenza vaccine (contains B/Victoria strain), Trivalent influenza vaccine (contains B/Yamagata strain)
- Where
- 2 sites in China
- Volunteers
- 2,340 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Self Efficacy, Nursing Caries
Effectiveness of Delirium Simulation Education of Nurses in Intensive Care Unit
Delirium is a common symptom in the intensive care unit, which greatly affects the prognosis of critically ill patients and increases medical costs.
- Conditions
- Self Efficacy, Nursing Caries, Intensive Care Unit Delirium, Simulation of Physical Illness
- Trial name
- NCT05333354
- Testing
- education strategy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Chronic Periodontitis
Autologous Alveolar Bone Marrow Mesenchymal Stem Cells for the Reconstruction of Infrabony Periodontal Defects
Systemically healthy periodontitis patients are recruited from new referrals to the Department of Periodontology and Biology of Implants, AUTh.
- Trial name
- PerioRegen (NCT02449005)
- Testing
- BM-MSCs/fibrin glue/collagen fleece, Fibrin glue/collagen fleece, Open flap debridement
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Treatment of Cognitive Deficits After Traumatic Brain Injury
Memantine Hydrochloride for Treatment of Cognitive Dysfunction Due to Traumatic Brain Injury
Posttraumatic consequences are common causes of disability and long-term morbidity. They include cognitive dysfunction, seizures, headache, dizziness, fatigue, sensory deficits, neurodegeneration and psychiatric disorders (e.g.
- Trial name
- NCT06337994
- Testing
- Memantine Hydrochloride
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Caries, Dental
Comparing Hall vs Conventional Technique in Placing Preformed Metal Crowns From Sudan
Preformed metal crowns (PMCs) have high success rates in restoring primary molars in children but they were not generally used by dentists, especially in developing countries due to its demand of high clinical skills with the…
- Trial name
- NCT03640013
- Testing
- Hall Technique PMC
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Khartoum Centre for Research and Medical Training
Deficiencies Micronutrient, Nutrition Disorders
Effect of Consuming Vitamin A-fortified Sugar on Serum Retinol Levels in Children
The increase in vitamin A deficiency (<20 mcg/dL) among children under five in Colombia (2010-2015) is a public health problem (27.3%).
- Trial name
- NCT07860060
- Testing
- white sugar fortified with retinol, refined white sugar for culinary use
- Where
- Colombia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Preoxygenation
Pre-Oxygenation Techniques in Pregnancy
A trial comparing outcomes of two pre-oxygenation techniques in obstetric patients.
- Trial name
- POP (NCT03310723)
- Testing
- Face Mask preoxygenation, OptiFlow preoxygenation
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Crowding of Anterior Mandibular Teeth
Mechanical Properties and Clinical Efficacy of Two Nickel-Titanium (NiTi) Archwires
Objective: to compare the changes of the mechanical properties measured by tensile test and three point bending test of two NiTi archwires (heat-activated and superelastic); when exposed to the oral conditions during the first…
- Trial name
- (NiTi) (NCT03256279)
- Testing
- .014" NiTi heat-activated archwire, .014" NiTi Superelastic archwire
- Where
- Colombia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
Osteoarthritis Pain
Study to Evaluate ATP-induced Pain and ATP-induced Dermal Vasodilation by Iontophoresis (0000-118)(COMPLETED)
This study will evaluate ATP-induced Pain (AIP) and ATP-induced dermal vasodilation (AIDV) as target engagement tools for future development of analgesics.
- Trial name
- NCT00917696
- Testing
- Comparator: Iontophoresis and Laser Doppler with ATP, Comparator: Iontophoresis and Laser Doppler with Saline
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy
Phase 1 Study to Assess the Safety of Inactivated Split Influenza Vaccine and Control Vaccine in Korean Volunteer
The purpose of this study to evaluate the safety of IL-YANG Inactivated Split Influenza Vaccine (IL-YANG FLU Vaccine Prefilled Syringe INJ.) in comparison with Fluarix Prefilled Syringe (inactivated split influenza vaccine) after…
- Trial name
- NCT02330003
- Testing
- IL-YANG FLU Vaccine Prefilled Syringe INJ., Fluarix Prefilled Syringe
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Il-Yang Pharm. Co., Ltd.
Liver Cancer
Irreversible Electroporation(IRE) For Unresectable Portal Venous Tumor Emboli
The purpose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for unresectable Portal venous tumor emboli.
- Trial name
- IRE (NCT02333773)
- Testing
- Irreversible electroporation (IRE)
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Stroke
The Evaluation of Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of JPI-289 in Healthy Male Volunteers
Double blind, randomized, placebo control, multiple dose, dose escalation study
- Trial name
- NCT02396069
- Testing
- JPI-289
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Major Depressive Disorder
Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.
In this project we aim to further refine indications for the use of the thyroid hormone - T3 for patients suffering from depression.
- Trial name
- NCT00421369
- Testing
- sertraline, triiodothyronine (T3), reboxetine
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Fat Disorder, Fat Redistribution
Effect of Tecartherapy in the Treatment of Localized Fat and Sagging Abdominal Skin - Clinical and Experimental Study
The excess of localized fat causes changes in the body contour and consequently changes in the properties of the skin and in the connective tissue, providing sagging skin.
- Trial name
- Tecarterapy (NCT05020054)
- Testing
- Tecartherapy Intervention
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Indústria Brasileira Equipamentos Médicos - IBRAMED
HIV Infections, Preexposure Prophylaxis (PrEP)
Clinical Decision Support for PrEP
Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the federal initiative to end the HIV epidemic. However, healthcare providers lack tools to identify patients who are at increased risk for HIV infection and…
- Trial name
- PrEDICT (NCT05245201)
- Testing
- Standard of care, Clinical decision support for PrEP
- Where
- 3 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Harvard Pilgrim Health Care
Healthy Person
DDI Study of Orelabrutinib
This is a phase I, single-center, open-label, fixed-sequence clinical study. The primary objective was to evaluate the effects of multiple administrations of rifampin or itraconazole on the pharmacokinetic characteristics of a…
- Trial name
- NCT05316857
- Testing
- Orelabrutinib + Rifampin, Orelabrutinib + Itraconazole
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Beijing InnoCare Pharma Tech Co., Ltd.
Stain Removal Efficacy
Clinical Comparison of the Stain Removal Efficacy of Two Air Polishing Powders
This study was designed to find out the stain removal efficacy and also, to find out the operators and patients opinion when use or receive treatment with both air polishing powders.
- Trial name
- NCT03140436
- Testing
- sodium bicarbonate powders with grain size 65 µm, sodium bicarbonate powders with grain size 40 µm
- Where
- Thailand
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy
Clinical Study for the Evaluation of the Depigmenting Activity of a Cosmetic Product on Spotted Hand Skin
Aim of the study was to evaluate by instrumental measurements the depigmenting activity of a cosmetic treatment for spotted hand skin; in particular it was investigated the synergic activity of an emulsion, with…
- Trial name
- NCT02204436
- Testing
- Emulsion and gel
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Healthy
Clinical Evaluation of Spring-Type Laparoscopic Clip Technology
The Visu-Loc spring clip is being used to occlude the cystic duct at the time of laparoscopic cholecystectomy. A hepato-iminodiacetic acid (HIDA) scan will be completed on post operative day one to check for biliary leaks.
- Trial name
- NCT00527644
- Testing
- 5mm spring clip
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Philadelphia Negative Myeloproliferative Neoplasms
Cardiovascular Manifestations in Ph-negative MPN
The primary aim of this research is to investigate the clinical and subclinical cardiovascular complications and its relationship with myeloproliferative neoplasms seeking to assess incidence, prevalence and severity in…
- Trial name
- NCT06615414
- Testing
- participants are not assigned an intervention as part of the study
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
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