Clinical trials: Clinical
Edentulous Alveolar Ridge
Two-piece Zirconia Implants With Two Various Platforms
24 patients with missing premolar teeth and healed sockets will be recruited. They will be randomized into two groups to supplied with tissue-level (n=12) or bone-level (n=12) 10-mm long 4-mm wide zirconia implants.
- Trial name
- ZircImpl (NCT06012071)
- Testing
- Zirconia dental implants
- Where
- Slovenia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Prediabetes, Hyperglycemia
Benefit of IQP-VV-102 in Reducing Postprandial Glucose Level in Overweight Caucasian Subjects
In this trial, the investigational product , the active ingredients which has been proven to reduce postprandial glucose in healthy and diabetic patients, will be tested.
- Trial name
- NCT02541344
- Testing
- Dose 1 of IQP-VV-102, Dose 2 of IQP-VV-102
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Overweight and Obesity
Effect of Açaí Juçara Consumption on Endothelial Function and Arterial Stiffness
This study evaluates the consumption of Açaí Juçara pulp in endothelial function and arterial stiffness in overwheight and obese individuals.
- Trial name
- NCT04434534
- Testing
- Hipocaloric Diet with Açaí Juçara, Hipocaloric Diet
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
MELAS Syndrome, Mitochondrial Respiratory Chain Deficiencies
Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers
The purpose of this First In Human study is to investigate the safety and tolerability of KL1333 after a single oral dose and to investigate the pharmacokinetic characteristics of KL1333 after a single oral dose.
- Trial name
- NCT03056209
- Testing
- KL1333 25 mg, KL1333 50 mg, KL1333 100 mg
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yungjin Pharm. Co., Ltd.
Pulpitis - Irreversible
Full Pulpotomy Versus Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
Background The European Society of Endodontology (ESE) and the American Association of Endodontists (AAE) position statements on the management of deep caries and exposed pulp recommended adoption and promotion of strategies…
- Trial name
- NCT06002698
- Testing
- Root canal treatment (Control), Full pulpotomy (Experimental)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Drug Safety
Clinical Safety of a Novel Milk Protein Peptide
Background: A novel milk peptide has been shown in laboratory setting to have natural anti-cancer properties and extend lifespan and improve metabolism in animal models.
- Trial name
- NCT01412658
- Testing
- Hydrolyzed milk protein mixture
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Ambryx Biotechnology
Emotional Dysregulation
Effectiveness and Security Testing of a Mobile App for Self-Managing Emotion Dysregulation
To assess the effectiveness and security of a mobile App (beta version) for people with borderline traits recruited from a non-clinical population of college students in Barcelona (Spain).
- Trial name
- NCT04210648
- Testing
- Mobile app
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari del Maresme
Amyotrophic Lateral Sclerosis
Studies in Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Motor Neuron Disorders
The purpose of this study is to collect, from patients with sporadic and familial ALS and their family members, clinical data and blood samples for extraction of DNA, RNA, preparation of lymphocytes, plasma and serum to establish…
- Trial name
- NCT05474235
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nasolabial Folds
Hyaluronic Acid Filler IMD1 Basic for Correction of Nasolabial Folds
Volunteers receive one injection IMD1 basic of correction of nasolabial folds and are followed-up for up to 36 weeks.
- Trial name
- NCT00429520
- Testing
- Hyaluronic acid filler/IMD1 basic
- Where
- Germany
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Influenza, SARS-CoV-2
A Clinical Study to Investigate the Safety and Immunogenicity in Relation to Product Attributes of mRNA-1083 (Severe Acute Respiratory Syndrome Coronavirus 2 [SARS-CoV-2] and Influenza Vaccine)
The purpose of this study is to evaluate the safety, reactogenicity, and immunogenicity in relation to the product attributes of mRNA-1083 vaccine when administered as a single intramuscular (IM) injection in adults ≥50 to <65…
- Trial name
- NCT06508320
- Testing
- mRNA-1083
- Where
- 17 sites in United States, Canada
- Volunteers
- 931 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Interimplant Mucosa
Clinical Evaluation of Vertical Inter-implant Papilla Height in Platform Matched Implants in Comparison to Morse Connection Abutments
The complete fill of the inter-implant mucosa is much more challenging between two implants, than single implants, and is considered to be unpredictable (Tymstra et al., 2011).
- Trial name
- NCT03787355
- Testing
- Morse connection Implants
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nursing Education, Competency-Based Education
Blockchain-Enabled E-Portfolios for Competency Tracking in Undergraduate Nursing Education: A Randomized Controlled Trial
This study evaluates whether a blockchain-enabled electronic portfolio can improve competency tracking and lifelong learning in undergraduate nursing education.
- Conditions
- Nursing Education, Competency-Based Education, Electronic Portfolios, Lifelong Learning
- Trial name
- BCEP-RCT (NCT07531355)
- Testing
- Blockchain-Enabled E-Portfolio Platform, Conventional Moodle-Based E-Portfolio
- Where
- Saudi Arabia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cairo University
Noncarious Cervical Lesions
Preheated Composites Vs. Conventional Composites in Noncarious Cervical Lesions
Preheating resin composites is the warming of resin composites by using a heating device (composite warmer) before its placement. Preheating increases the flow properties and allows better adaptation to cavity preparation.
- Trial name
- NCT05533255
- Testing
- Conventional composite resin (3M™ Filtek™ Z350 XT Universal Restorative), Preheated composite resin (3M™ Filtek™ Z350 XT Universal Restorative)
- Where
- Malaysia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Manipal University College Malaysia
Snorer
Randomized Controlled Trial of TCRFVR and LAUP in Snorers
We hypothesis that radiofrequency will cause less post-operative discomfort when compared with laser assited uvulopharyngoplasty. 40 patients with primary snore will be enrolled into this study.
- Trial name
- NCT00202943
- Testing
- TCRFVR and LAUP
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Denture Retention
A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers
The purpose of this study is to evaluate a methodology to determine the ability of a denture adhesive to restrict food ingress underneath dentures during eating.
- Trial name
- NCT03345108
- Testing
- Denture Adhesive Cream (Conventional Application), Denture Adhesive (Continuous Strip Application), No Adhesive
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acute Bacterial Skin and Skin Structure Infection (ABSSSI), Prosthetic Joints Infection (PJI)
Phase 1, Single-Dose and Multiple-Dose Continuous Intravenous Infusions of TNP-2092 for Injection in Healthy Chinese Participants
This is a phase 1, single-center, randomized, double-blind, placebo-controlled, dose-escalation clinical trial of single and multiple intravenous doses of TNP-2092 for injection in healthy Chinese participants.
- Trial name
- NCT06394518
- Testing
- TNP-2092 for injection
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TenNor Therapeutics Inc.
Mood Disorder, Anxiety Disorder
Validation of an Automated Online Language Interpreting Tool - Phase Two.
There is a pressing national need to provide higher-quality, more effectively accessible language interpretation services to improve the health outcomes of Americans who have limited English proficiency (LEP).
- Conditions
- Mood Disorder, Anxiety Disorder, Substance Use Disorder, Chronic Medical Condition
- Trial name
- NCT03538860
- Testing
- Active comparator: Human interpreter, Intervention: Asynchronous Telepsychiatry
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Pulpotomy of Young Permanent Molars
Clinical and Radiographic Evaluation of Three Biomimetic Materials in Pulp Therapy of Immature Young Permanent Teeth "A Randomized Controlled Clinical Trial"
Statement of the problem: Pulpotomy is the most popular technique for maintaining vitality and has a substantial impact on continuing root growth in vital, young permanent molars suffering from dental cavities.
- Trial name
- NCT07207382
- Testing
- MTA group, Premixed Bioceramic material, Treated Dentin Matrix
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Metabolic Syndrome
Low Carbohydrate Diet Versus Low Fat Diet in Reversing the Metabolic Syndrome Using NCEP ATP III Criteria
The National Cholesterol Education Program Adult Treatment Panel-III (NCEP ATP III) definition of metabolic syndrome (MetS)is one of the most widely used criteria of metabolic syndrome.
- Trial name
- NCT04681924
- Testing
- Diet intervention
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Pulpitis, Pulp Disease, Dental
Bioactive Materials in Pulp Therapy of Primary Teeth
The purpose of this study is to compare the clinical and radiographic success of a new injectable, fast setting bioceramic root repair material (BC RRM) putty with mineral trioxide aggregate (MTA) in pulpotomy procedures of…
- Trial name
- NCT04795830
- Testing
- Bioceramic root repair material as pulp dressing in pulpotomy in primary molars, Mineral Trioxide Aggregate as pulp dressing in primary molars (MTA)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
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