Clinical trials: Clinical
Cough
Codeine Phosphate/Guaifenesin ER Tablet 30 mg/600 mg Steady State Clinical Study
The objectives of this pivotal study are: 1. to evaluate bioavailability of an extended-release and immediate release Codeine Phosphate/Guaifenesin tablet at steady state following multiple oral administration 2.
- Trial name
- COGUSS (NCT02572375)
- Testing
- Codeine Phosphate/Guaifenesin ER Tablet, Codeine Phosphate/Guaifenesin IR Tablet
- Where
- Jordan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Nexgen Pharma, Inc
Discoloration, Tooth
One Year Clinical Evaluation of E-max CAD and Lava Ultimate Laminate Veneers
Restoration of anterior teeth using conservative approach allows clinicians to provide porcelain laminate veneers with excellent esthetics without extensive tooth structure removal.
- Trial name
- NCT03086928
- Testing
- lava ultimate, E.max cad
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hepatitis A
The Fifth-year Follow-up Study for the Phase IV Clinical Trial of Hepatitis A Vaccine in Healthy Children
The purpose of this follow-up study is to evaluate the five-year immune persistence of one injection of inactivated and attenuated alive hepatitis A vaccine in healthy children.
- Trial name
- NCT02002065
- Testing
- Inactivated HAV vaccine, Attenuated alive HAV vaccine
- Where
- China
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Implant Site Reaction
Peri-implant Soft Tissue Conditioning of Immediate Posterior Implants by CAD/CAM Socket Sealing Abutments
One of the major challenges one clinician can face while performing immediate placement on posterior area, is the ability of obtaining a hermetic primary closure of the soft tissue.
- Trial name
- NCT05276765
- Testing
- cad/cam socket sealing abutment, standard healing abutment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Visual Acuity
Post-Market Study of Alcon Intraocular Lenses
The purpose of the study is to evaluate clinical and functional performance in real-world conditions in participants who have been implanted with Acrysof IQ Vivity (Extended Vision) IOLs compared with Alcon Aspheric Monofocal…
- Trial name
- NCT05414565
- Testing
- Vivity IOL, Aspheric monofocal IOL
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Clinical Reasoning in Nursing Education
Comparative Case Learning in Undergraduate Nursing Students
This randomized controlled educational trial compares two ways of teaching undergraduate nursing students to reason through clinical cases.
- Trial name
- NCT07829965
- Testing
- Comparative Case Learning Educational Package, Individual Case Reasoning Educational Package
- Where
- Turkey (Türkiye)
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Agri Ibrahim Cecen University
Infertility, Implantation Rate
Hyaluronan-enriched Medium and Euploid Blastocyst Transfers
It has been proposed that enriching transfer media with hyaluronan (EmbryoGlue medium) improves pregnancy outcomes compared with media containing lower concentrations of this molecule.
- Conditions
- Infertility, Implantation Rate, Clinical Pregnancy Rate, Live Birth Rate
- Trial name
- GluePloid (NCT06165367)
- Testing
- EmbryoGlue Medium
- Where
- United Arab Emirates
- Volunteers
- 783 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Non-small Cell Lung Cancer Metastatic
Camrelizumab Combination With SBRT and Concurrent Chemotherapy Treated Stage IV Oligometastatic Non-small Cell Lung Cancer
This study evaluated the effectiveness and safety of Camrelizumab combination with SBRT and concurrent chemotherapy treated stage IV oligometastatic non-small cell lung cancer
- Trial name
- IMCORT-2 (NCT05472467)
- Testing
- Camrelizumab, stereotactic body radiation therapy, Chemotherapy
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Gingival Destruction
Assessing the Clinical Efficacy of Hyaluronic Acid Hydrogel in Papilla Augmentation: A Clinical Study.
The aim of this study is to evaluate the effect of hyaluronic acid gel in papilla augmentation.
- Trial name
- NCT06447311
- Testing
- Hyaluronic acid gel
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr R Viswa Chandra
Hepatic Impairment
Pharmacokinetics and Safety of Levornidazole Disodium Phosphate for Injection in Chinese Patients With Hepatic Impairment
Objective： To evaluate the pharmacokinetics and safety of a single intravenous dose of levornidazole disodium phosphate for Injection in subjects with mild hepatic impairment (Child-Pugh A), moderate hepatic impairment…
- Trial name
- NCT07906171
- Testing
- Levornidazole Disodium Phosphate for Injection
- Where
- 3 sites in China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd
Sedentary Behavior
Short Moderate-intensity Continuous Training on Sedentary Women's
Purpose: To determine the effects of three Short Moderate Intensity Continuous Training (SMICT) exercise programs with different durations, on functional capacity, resting heart rate (RHR) and physical activity enjoyment in…
- Trial name
- NCT06242899
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Colonoscopy
Will Cap-Assisted Colonoscopy Improve Performance of Colonoscopy: A Randomized Clinical Trial
Observing the effects of an Olympus cap on the visibility and in adenoma detection during colonoscopy.
- Trial name
- CAC (NCT01126632)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Opioid-use Disorder, Overdose of Opiate
Patient Reported Outcomes for Opioid Use Disorder
The goal of the project is to build a clinical data research infrastructure that will begin to enhance capacity to use electronic health record (EHR) data and patient reported outcomes measures (PROs) to conduct opioid related…
- Conditions
- Opioid-use Disorder, Overdose of Opiate, Patient Participation
- Trial name
- NCT03985163
- Testing
- Patient Reported Outcomes Electronic Survey
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Yale University
Marfan Syndrome
Clinical Variability in Marfan Syndrome
Marfan syndrome is an autosomal dominant connective tissue disorder caused by mutations in the fibrillin-1 gene (FBN1). Penetrance of FBN1 mutations is complete but intra and inter familial clinical expressivity is extremely…
- Trial name
- Variarfan (NCT01707563)
- Testing
- skin punch biopsy and molecular biology, fibroblast culture and molecular biology
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gingival Recession
Treatment of Miller Class I and II Gingival Recession Using Non- Pedicled Buccal Fat Pad Graft as Compared to Subepithelial Connective Tissue Graft
This randomized controlled single blinded parallel clinical trial is held to monitor if the use of the non pedicled buccal fat pad graft will result in post operative pain as a primary outcome compared to that occurs with the use…
- Trial name
- NCT03543163
- Testing
- Non- Pedicled Buccal Fat Pad with Coronally Advanced flap, sub-epithelial connective tissue graft
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Safety Markers of Adjuvanted Influenza Vaccine
Placebo Controlled Study to Generate Data Characterising Clinical Events, Physiological Responses and Immune Responses
The purpose of this protocol is to generate a set of data that will be analysed by integrated systems biology approach, for validation in subsequent clinical trials or in animal models.
- Trial name
- NCT02523287
- Testing
- Fluad, Saline
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Diabetes Mellitus, Type 2
Clinical Verification of Peptide Biomarkers for Type 2 Diabetes Mellitus
Although diabetes has been controlled since insulin became available, it is still considered incurable and poses serious threats to human health.
- Trial name
- NCT01902316
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Beijing Institute of Technology
Molar Incisor Hypomineralization
Comparing CAD/CAM vs Composite for Carious Hypomineralized Molars Evaluating Clinical Outcomes of Both Treatments.
Molar Incisor Hypomineralization (MIH) is enamel hypomineralization defined as qualitative defects caused by disruptions in either the calcification or maturation phases of amelogenesis affecting one or more first permanent…
- Trial name
- NCT07049016
- Testing
- restoring the MIH affected young permanent molars using Direct nanohybrid flowable composite, restoring the MIH affected young permanent molars using IPS e.max CAD
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Irreversible Pulpitis
Success and Quality of Life Following Complete Pulpotomy and Root Canal Treatment
The purpose of this study is to compare the Success and quality of life following complete pulpotomy and root canal treatment in teeth with clinical signs indicative of irreversible pulpitis.
- Trial name
- NCT05190406
- Testing
- Pulpotomy, root canal treatment
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Invasive Cancer, Healthy Volunteer
A Prospective, Multi-center Clinical Study to Establish Multi-Cancer Early Detection Platform Through the Analysis of Whole Genome Sequencing of Circulating DNA in Cancer Patients and Healthy Volunteers
This is a prospective, multi-center clinical study of Multi-Cancer Early Detection (MCED) testing in cancer patients and healthy volunteers.
- Trial name
- NCT06231953
- Where
- South Korea
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Yonsei University
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