Clinical trials: Clinical Anxiety
Obsessive-Compulsive Disorder
Safety and Efficacy of Pramipexole Treatment in Resistant Obsessive-Compulsive Disorder (OCD)
The most common and effective treatment for OCD is pharmacological therapy that includes selective serotonin reuptake inhibitors (SSRIs) antidepressants and, in the case of patients resistant to this approach, a combination with…
- Trial name
- OCD-RT (NCT06611592)
- Testing
- Pramipexole 0.088mg/tid, Pramipexole 0.18 mg/tid, Pramipexole 0.35 mg/tid
- Where
- Portugal
- Volunteers
- 48 people
- Sponsor
- Clinical Academic Center (2CA-Braga)
Kinesiophobia (Fear of Movement), Rhematoid Arthritis
Kinesiophobia in Rheumatoid Arthritis: Associations With Functional Disability, Disease Activity, and Related Clinical Factors
Objectives: Impairment of physical function is a core feature of RA, particularly in patients with high disease activity where pain and inflammation directly limit movement.
- Conditions
- Kinesiophobia (Fear of Movement), Rhematoid Arthritis, Rheumatoid Arthritis (RA), Rheumatoid
- Trial name
- NCT07435272
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Minia University
S-ketamine, Esketamine
Safety and Efficacy Evaluation of S (+) - Ketamine in Children
A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in children in perioperative settings.
- Conditions
- S-ketamine, Esketamine, Acute Pain, Postoperative Pain
- Trial name
- NCT04834427
- Testing
- Conventional therapy + S (+)-Ketamine, Conventional therapy
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Chinese PLA General Hospital
Anesthesia, Local
Conventional Versus Computer-Assisted Dental Anesthesia
The purpose of this clinical trial was to compare two methods of delivering local dental anesthesia in undergraduate dental students: a computer-controlled local anesthetic delivery (CCLAD) system and a conventional dental…
- Trial name
- NCT07731503
- Testing
- Computer-Controlled Local Anesthetic Delivery System, Conventional Aspirating Dental Syringe
- Where
- Mexico
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Montemorelos
Anxiety
Clinical Study of Oral Midazolam Combined With Esketamine Administered Intranasally for Pediatric Preoperative Sedation
Children are prone to anxiety and even fear before surgery, and such adverse emotions may not only lead to poor induction of anesthesia, but also increase the incidence of postoperative agitation and even lead to postoperative…
- Trial name
- NCT05925283
- Testing
- Midazolam, Esketamine, midazolam and esketamine
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Social Phobia
Social Anxiety Disorder Study Of Paroxetine
This study is designed to evaluate the efficacy and safety in Social Anxiety Disorder (SAD).
- Trial name
- NCT00318669
- Testing
- Paroxetine hydrochloride hydrate
- Where
- 16 sites in Japan
- Volunteers
- 390 people
- Sponsor
- GlaxoSmithKline
Anxiety, Stress
The Effect of Music Therapy and Progressive Muscle Relaxation Exercise on Anxiety Before the First Clinical Practice
This study was carried out to evaluate the effect of music therapy and progressive muscle relaxation exercise on the state and trait anxiety levels before their first clinical practice in nursing students.
- Trial name
- NCT04540172
- Testing
- Music Therapy, Progressive Muscle Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Concussion, Brain, Treatment
Modulating Exercise Dosage to Improve Concussion Recovery
Aerobic exercise has emerged as an effective treatment to reduce sport-related concussion symptom severity, yet existing work lacks rigor regarding the precise exercise volume and intensity required to elicit therapeutic effects…
- Conditions
- Concussion, Brain, Treatment, Aerobic Exercise, Inflammation
- Trial name
- MEDIC (NCT05434130)
- Testing
- High Dose Exercise
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- University of Colorado, Denver
Blood Pressure, Dental Anxiety
Hemodynamic Changes During Implant Surgery with Intravenous Conscious Sedation
The goal of this study is to determine whether intravenous sedation would contribute to the stabilization of hemodynamics in adult patients during periodontal/implant surgery compared to receiving local anesthesia during…
- Trial name
- NCT05756439
- Testing
- Intravenous Sedatives with or Without Analgesia, No IV sedation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Ventrogluteal Injection, Intramuscular Injection
Augmented Reality and 3D Model-Based Ventrogluteal Injection Training in Nursing Students (AR3D-VGI)
The aim of this study was to evaluate the impact of a skills training program-conducted using augmented reality (AR) and 3D model technologies-on first-year nursing students' knowledge, skills, anxiety, and satisfaction, as well…
- Conditions
- Ventrogluteal Injection, Intramuscular Injection, Nursing Education, Clinical Skills Training
- Trial name
- AR3D-VGI (NCT07583537)
- Testing
- Augmented Reality Group, 3D Model Group
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Post-COVID19 Condition
Effect of Vitamin D Supplementation on Glutathione Peroxidase (GPx) Activity, Interleukin-6 (IL-6) Levels and Clinical Outcomes in Post-COVID-19 Patients
The goal of this clinical trial is to evaluate the effectiveness of vitamin D supplementation in treating neuropsychiatric symptoms and improving antioxidant levels in individuals diagnosed with post-COVID-19 condition, a state…
- Trial name
- VITDPOSTCOVID (NCT06419712)
- Testing
- vitamin D (cholecalciferol) supplementation
- Where
- Mexico
- Volunteers
- 54 people
- Sponsor
- Escuela Militar de Graduados de Sanidad, SEDENA
Molar Incisor Hypomineralization
Digital Intraosseous Anesthesia in MIH-Affected Permanent Molars
This multicentre, randomized clinical trial compared digital intraosseous anaesthesia with conventional local anaesthetic techniques in children aged 6-12 years receiving restorative treatment for MIH-affected permanent first…
- Trial name
- DIA-MIH (NCT07736677)
- Testing
- SleeperOne 5 Computer-Controlled Intraosseous Anaesthesia System, Conventional Maxillary Infiltration Anaesthesia, Conventional Inferior Alveolar Nerve Block Anaesthesia
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ege University
Obsessive-Compulsive Disorder
EEG Evaluation of CBT for Obsessive-Compulsive Disorder
This clinical trial investigates how Cognitive Behavioral Therapy (CBT), a psychological treatment that helps people change their thought and behavior patterns, affects brain function in people diagnosed with Obsessive-Compulsive…
- Trial name
- CBT-OCD-EEG (NCT07000812)
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uskudar University
Woman Aged 18 to 65, Woman of Reproductive Age
Chewing Gum During a Pap Smear
This study, which was conducted to determine the effects of chewing gum on anxiety and pain during Pap smear, found that chewing gum reduced pain but had no effect on anxiety.
- Trial name
- NCT07124182
- Testing
- shewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Firat University
Anxiety Disorders, Depression
Emotional Impact of the Way Conducting Cancer Patients to the Surgical Center
Cancer is an extremely aggressive disease, anxiety and depression are consequences some patients may develop from diagnosis continuing during treatment. A measures control of the cancer is surgery for removal tumor.
- Trial name
- NCT03576482
- Testing
- Transport on foot
- Where
- Brazil
- Volunteers
- 176 people
- Sponsor
- Barretos Cancer Hospital
Functional Dyspepsia, Probiotics
Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia
Objective: This study aims to evaluate the effectiveness of Clostridium butyricum in improving anxiety and depression in patients diagnosed with functional dyspepsia according to the Rome IV criteria.
- Conditions
- Functional Dyspepsia, Probiotics, Depression, Anxiety
- Trial name
- NCT07182890
- Testing
- Clostridium butyricum
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Premenstrual Syndrome, Pilates Exercise
Clinical Pilates' Impact on Fitness, Symptoms & Kinesiophobia in PMS
Premenstrual syndrome (PMS) is characterized by a series of somatic and psychological symptoms of varying severity that occur during the luteal phase of the menstrual cycle, affecting approximately 30% of women and resolving with…
- Trial name
- NCT06835062
- Testing
- Recommendations for Enhancing General Well-Being, Clinical Pilates
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Magnetic Resonance Imaging
The Use of a Mock MRI Scanner for Reducing the Use of Anesthesia in Children Undergoing Clinical MRI Scans
Diagnostic Magnetic Resonance (MR) imaging procedures can be stressful for children and parents. Patients must lie still during the procedure to provide diagnostic quality images.
- Trial name
- NCT02630342
- Testing
- Mock MRI scanner, Preparation materials, Child Life Specialist preparation
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Calgary
Pain and Anxiety in Children With MIH
Preemptive Analgesia for Pain and Anxiety Control in Children With MIH
This randomized, triple-blinded clinical trial aims to evaluate the effect of preemptive analgesia using ibuprofen on pain perception and anxiety during restorative treatment of first permanent molars in children diagnosed with…
- Trial name
- NCT07374354
- Testing
- ibuprofen 100mg/ml oral suspension syrup
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- October University for Modern Sciences and Arts
Colorectal Cancer, Patient Satisfaction
Digital Education in Colorectal Cancer Patients
The goal of this clinical trial is to evaluate the impact of integrating video- based education in colorectal cancer surgery, with a specific focus on patient's perspective.
- Conditions
- Colorectal Cancer, Patient Satisfaction, Patient Engagement, Patient
- Trial name
- GUIDE (NCT07686133)
- Testing
- Video platform
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto