Clinical trials: Clinical Course
Moderate to Severe Psoriasis
Open Label Study of Alefacept Injections to Patients With Moderate to Severe Psoriasis
This is a single-center, open-label, pilot study. A total of 18 subjects will be enrolled in this 6 month study to evaluate whether the response to intralesional alefacept injections prior to the standard course of…
- Trial name
- NCT00678470
- Testing
- Intralesional Alefacept
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Response to Toxin, Toxicity
Two-week Course Versus Conventionally Fractionated Chemoradiotherapy in Rectal Cancer
The investigators compare two-week course of chemoradiation (33 Gy in 10 fractions with oral capecitabine) and conventional chemoradiation (50.4 Gy in 28 fractions with 5-FU and leucovorin) in this randomized trial.
- Conditions
- Response to Toxin, Toxicity, Recurrence
- Trial name
- NCT02484040
- Testing
- Two-week course of radiation
- Where
- South Korea
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Jong Hoon Lee
Inflammatory Bowel Diseases, Ulcerative Colitis
IBD Registry in a Sub-Saharan African Population
The investigators intend to establish a prospective registry of patients diagnosed with inflammatory bowel disease at Parirenyatwa hospital in Harare, Zimbabwe.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT04178408
- Testing
- No intervention
- Where
- Zimbabwe
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Medical Education
Analysis of the Effect of Pre-course Videos on Improving Clinical Skills in Emergency Ultrasound Training
Project Background Point-of-Care Ultrasound (POCUS) has become an important part of medical education in recent years. However, due to limited resources of ultrasound machines and clinical instructors, hands-on practice…
- Trial name
- CVC (NCT06947733)
- Testing
- pre-class videos, no pre-class videos
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Physical Assessment Skills
Enhancing Practical Competence in Physical Assessment Through Digital Video Feedback
This cluster randomized controlled trial aims to evaluate the effectiveness of a digital video feedback strategy in improving physical assessment skills, learning motivation, self-regulated learning, and anxiety among…
- Trial name
- NCT07825038
- Testing
- Digital Video Feedback Group, Traditional Physical Assessment Teaching
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Diaphragmatic Hernia
Fetoscopic Tracheal Balloon Occlusion in Left Diaphragmatic Hernia
Left diaphragmatic hernia detected during fetal life carries a high risk for postnatal lung failure due to lung underdevelopment and pulmonary hypertension.
- Trial name
- NCT00373438
- Testing
- Fetoscopic tracheal balloon occlusion
- Where
- Germany
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Lyme Disease, Erythema Migrans
Erythema Migrans in Elderly
The investigators will focus on elderly patients with early Lyme borreliosis with the aim of assessing clinical course, serological response and treatment outcome of the disease as compared to younger adults.
- Conditions
- Lyme Disease, Erythema Migrans, Elderly Infection
- Trial name
- NCT03371563
- Testing
- Antibiotics, no intervention
- Volunteers
- 1,220 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Mental Health, Child Wellbeing
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes.
- Conditions
- Mental Health, Child Wellbeing, Infant Health, Child Health
- Trial name
- GenV (NCT05394363)
- Where
- Australia
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Endothelial Dysfunction
Clinical Monitoring of Endothelial Dysfunction for Pregnant Women and in the Perioperative Course
A single- center prospective observational study. This study evaluates different aspects of endothelial function. It investigates the endothelial leakage with the venous occlusion plethysmography and the flow-mediated…
- Trial name
- NCT01311297
- Where
- Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Claudia Spies
Non IgE Mediated Food Allergy, Food Protein-Induced Enteropathy
Non-Immunoglobulin E-mediated Food Allergies in Children
Non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA) are an evolving web of clinical conditions characterized by subacute and/or chronic symptoms and include food protein-induced enterocolitis syndrome (FPIES), food…
- Conditions
- Non IgE Mediated Food Allergy, Food Protein-Induced Enteropathy, Food Protein-Induced Proctocolitis, Food Protein-Induced Enterocolitis Syndrome
- Trial name
- NIGEFA (NCT04462978)
- Testing
- Non IgE-mediated food allergy
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federico II University
Healthy
Gene Expression Profiles in Muscle After Immunisation
This clinical study is part of the BIOVACSAFE project which is funded by the Innovative Medicine Initiative. In this study we will take a small muscle biopsy in order to identify any differences in the response around the actual…
- Trial name
- NCT02368327
- Testing
- Fluad, Fendrix
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Surrey
HIV, Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
The Impact of Helicobacter Pylori Infection on Immune Regulation and Clinical Course in HIV Patients in Ghana
The main objective of the study is to investigate the impact of H. pylori infection on immune activation and clinical outcome in HIV patients. Other specific study objectives are: 1. To investigate the effects of H.
- Trial name
- HHECO (NCT01897909)
- Where
- Ghana
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Bernhard Nocht Institute for Tropical Medicine
Schizophrenia, Psychotic Disorders
Dimensional and Developmental Profiles of Psychosis in Children and Adolescents
Five collaborating sites in France will study the broad spectrum of schizophrenia in children and adolescents. Patients will be studied with diagnostic interviews, developmental histories, dimensional clinical ratings…
- Trial name
- PSYDEV (NCT04370730)
- Testing
- clinical, neuroimaging and DNA assessments
- Where
- 6 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rectal Cancer
Short-course Preoperative Chemoradiotherapy for Rectal Cancer
The purpose of this study is to evaluate the early clinical outcome of the short-course preoperative chemoradiotherapy, 33Gy/10 fx and delayed operation after chemoradiation, the investigators initiated the clinical trial of KROG…
- Trial name
- KROG 11-02 (NCT01431599)
- Testing
- short-course radiation
- Where
- 3 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jong Hoon Lee
VKH Syndrome
Immune Profile of Acute VKH Patients PBMC
The investigators will collect blood samples of different courses of VKH patients for investigating immune profile, observe major immune cells number ,functional and membrane molecular changes in the course of treatment, to…
- Trial name
- IPV (NCT04025476)
- Testing
- Steroids
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aier School of Ophthalmology, Central South University
Students
The Effectiveness of Using Empathy Courses to Guide OT Students in Case-base Clinical Reasoning
Clinical reasoning is an important cognitive process in medical decision making. In recent years, medical education advocates holistic medicine, but systematic learning is rare in school education.Therefore, this study used an…
- Trial name
- NCT05479110
- Testing
- Empathy experience courses and case-base clinical reasoning, case studies
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Microbiota
Descriptive Study of the Gene Count in Faecal Microbiota
The hypothesis of METARICH Study is that it is possible to draw up a profile of the faecal microbiota, which could contribute in the future to the characterisation of certain chronic pathologies.
- Trial name
- METARICH (NCT06955572)
- Testing
- Patients with colorectal cancer, Patients with Parkinson's disease, Patients with non-alcoholic steatohepatitis
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Educational Course
A Prospective Patient Education Program for IBD Patients
During the past few decades, key medical organizations have highlighted the importance of patient education and support. Evidence suggests that improving inflammatory bowel disease (IBD) patients' knowledge of their disease may…
- Trial name
- NCT05168345
- Testing
- Course and web information
- Where
- Israel
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Shigella Sonnei Infection
The Long Term Clinical Course of Postinfectious Irritable Bowel Syndrome After Shigellosis; A 10 Year Follow up Study
Background: The incidence of postinfectious irritable bowel syndrome (PI-IBS) was reported to be in the range of 5-30%, but limited number of long-term follow-up results.
- Trial name
- NCT02516683
- Testing
- Shigella sonnei infection
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Varicella
Safety and Immunogenicity of Live Attenuated Varicella Vaccine in Healthy Population Aged ≥13 Years Old
This a randomized, blind, controlled clinical trial of live attenuated varicella vaccines manufactured by Sinovac (Dalian) Vaccine Technology Co., Ltd .The purpose of this study is to evaluate the immunogenicity of a two doses…
- Trial name
- NCT05015686
- Testing
- Live attenuated varicella vaccines manufactured by Sinovac (Dalian) Vaccine Technology Co., Ltd, Live attenuated varicella vaccines manufactured by Changchun BCHT Biotechnology Co.,Ltd
- Where
- China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Sinovac (Dalian) Vaccine Technology Co., Ltd.