Clinical trials: Clinical Disease and/or Syndrome
Eye Diseases, Eye Infections
The EXPLORE Study - The Use of Binocular OCT Imaging for the Assessment of Ocular Disease
Optical coherence tomography (OCT) is an imaging modality, first described in 1991, that provides cross-sectional images of the eye in a non-invasive manner.
- Conditions
- Eye Diseases, Eye Infections, Eye Inflammation
- Trial name
- NCT03553017
- Testing
- Binocular OCT
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University College, London
Chronic Pancreatitis Pancreatic Exocrine Insufficiency Blood Glucose
A Study on the Changes of Glucose Metabolism and Exocrine Function in Patients With Chronic Pancreatitis
This study aims to investigate the impact of pancreatic exocrine insufficiency on the glucose profile and pancreatic and gastrointestinal endocrine hormones in patients with chronic pancreatitis through pancreatic enzyme…
- Trial name
- NCT07314489
- Testing
- Creon（Pancreatin Enteric-coated Capsules）
- Where
- 2 sites in China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
Explore Biomarkers of Motor Neuron Disease/Frontal Dementia Spectrum Disease in China
1. To investigate the biomarkers of MND/FTD spectrum disease 2. To explore the possible pathogenesis of MND/FTD
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Motor Neuron Disease
- Trial name
- NCT04961450
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Peking University Third Hospital
Cervical Cancer, Genital Warts
Alternate Dosing Schedules Study for HPV Vaccine
To determine if delayed dosing of recombinant human papillomavirus (HPV) quadrivalent (Types 6, 11, 16, and 18) vaccine in 9-18 year old girls elicits an equivalent immune response (geometric mean titers to HPV 6,11,16, and 18 as…
- Trial name
- ADS (NCT00862810)
- Testing
- Received HPV vaccine first, Received concomitant vaccines first
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Duke University
Epileptic Seizures Related to Drugs, SARS-CoV-2 Acute Respiratory Disease
Epileptic Seizure in Epilepsy Patients After SARS-CoV-2 Vaccination
Background and Objectives: Seizure attack is one of adverse effects of vaccination in epileptic patients, the risk of which after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inoculation was elucidated in the…
- Conditions
- Epileptic Seizures Related to Drugs, SARS-CoV-2 Acute Respiratory Disease, Vaccine Adverse Reaction
- Trial name
- NCT05341713
- Testing
- inactive SARS-Cov-2 vaccine
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital
Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester
Tidal Neonatal NO, Vitamins A and D, and Infant Lung Disease - The AD-ON Study
Children born prematurely are of greater risk of developing chronic lung disease (Bronchopulmonary Dysplasia). With an increase in the amount of premature children, we expect an increasing number of children with BPD.
- Conditions
- Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester, Bronchopulmonary Dysplasia
- Trial name
- NCT01722760
- Testing
- measurements
- Where
- 2 sites in Denmark
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Behcet's Syndrome, Intestinal Type
Pathogenesis of Intestinal Behcet's Syndrome
There is a direct interaction between food, intestinal flora and the intestinal barrier composed of intestinal epithelial cells and mucosal immunity, whose composition and functional alterations are theorized to be closely…
- Trial name
- NCT06026020
- Testing
- Biological samples collection
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Alzheimer's Disease, Mild Cognitive Impairment
Alzheimer's Disease Core Center
The main objective of this research project is to provide a comprehensive clinical database of patients with Alzheimer's disease (AD) and other forms of dementia, individuals with mild cognitive impairment (MCI), and age-matched…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Age-Related Memory Disorders
- Trial name
- ADCC (NCT01421420)
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Sarcoidosis, COVID-19
Number of Participants Diagnosed With Sarcoidosis by Bronchoscopic Transbronchial Needle Aspiration After COVID- 2019 .
The goal of this observational study is to learn about sarcoidosis development after COVID-19 infection. The main question it aims to answer is: prevalence of Sarcoidosis among patients previously infected with COVID-19.
- Trial name
- NCT06043882
- Testing
- flexible bronchoscopy
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Ain Shams University
Hodgkin's Lymphoma
Study of MGCD0103 (MG-0103) in Patients With Relapsed or Refractory Hodgkin's Lymphoma
MGCD0103 is an experimental drug that belongs to a class of drugs known as the histone deacetylase inhibitors, which may restore normal control in cancer cells by affecting the genes and proteins that are being made.
- Trial name
- NCT00358982
- Testing
- MGCD0103
- Where
- 5 sites in United States, Canada
- Volunteers
- 51 people
- Sponsor
- Mirati Therapeutics Inc.
Graft-vs-host Disease
Preemptive Therapy of GVHD
Graft-vs-host disease (GVHD) causes substantial mortality, morbidity and poor quality of life after blood or marrow transplantation (BMT).
- Trial name
- NCT01994824
- Testing
- rabbit antithymocyte globulin
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Calgary
Ergocalciferol
Pilot Study: The Effect of Ergocalciferol on Plasma Mucin-1 Levels
To determine if a one-time oral administration of ergocalciferol results in a decline in plasma mucin-1 levels in healthy individuals and individuals with ADTKD-MUC1.
- Trial name
- NCT03747523
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Chronic Obstructive Lung Disease
Evaluation of Breathe NIOV System on Work of Breathing in Chronic Obstructive Lung Disease Patients
The Breathe Ventilator is a lightweight, wearable ventilator that has received U.S. FDA clearance for use in patients with respiratory difficulty.
- Trial name
- NCT01596023
- Testing
- Breathe NIOV Ventilator
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Breathe Technologies, Inc.
Infection, Heart Failure
Hospital-Level Care at Home for Acutely Ill Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Infection, Heart Failure, COPD, Asthma
- Trial name
- NCT03203759
- Testing
- Home hospitalization, Traditional inpatient hospitalization
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- Brigham and Women's Hospital
COPD (With - Without Rehabilitation)
Effects of Structural Integration on Chest Wall Expansion Among COPD Patients
The present study aims to investigate the effects of the 10-Series of Structural Integration on chest wall expansion in patients with stable COPD using a randomized controlled trial design.
- Trial name
- NCT07752420
- Testing
- Structural Integration with Conventional Pulmonary Rehabilitation, Pulmonary Rehabilitation only
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Green International University
Myocardial Ischemia
Sex and Gender Differences in Ischemic Heart Disease - Endocrine Vascular Disease Approach
The application of sex-gender medicine is strongly recommended by World Health Organization and other international organization.
- Trial name
- EVA (NCT02737982)
- Testing
- percutaneous coronary intervention
- Where
- Italy
- Volunteers
- 509 people
- Sponsor
- University of Roma La Sapienza
Abdominal Aortic Aneurysm
Prevalence and Screening of Abdominal Aortic Aneurysms Among Men With Coronary Artery Disease
The purpose of this study is to investigate the prevalence of abdominal aortic aneurysms (AAA) among male patients with coronary artery disease (CAD) verified in coronary angiography.
- Trial name
- CAD-AAA (NCT01897623)
- Testing
- ultrasound of aorta
- Where
- Finland
- Sponsor
- North Karelia Central Hospital
Heart Defects, Congenital, Cardiovascular Disease Other
Congenital Heart Disease Physical Activity Lifestyle Study V.2
The Congenital Heart Disease Physical Activity Lifestyle Intervention Study (CHD-PALS) V.2 seeks to determine the efficacy of a lifestyle intervention program for adolescents and young adults (AYAs) with congenital heart disease…
- Trial name
- CHD-PALS V2 (NCT06003023)
- Testing
- Physical Activity Monitoring, Tailored Exercise Prescription, Healthy Lifestyle Education
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Jamie Jackson
Chronic Obstructive Pulmonary Disease
Physical Activity Counseling During Pulmonary Rehabilitation
This randomized controlled trial will assess the effect of adding intensive physical activity counseling to an outpatient pulmonary rehabilitation program.
- Trial name
- PAC (NCT00948623)
- Testing
- physical activity counseling program
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- KU Leuven
Coronary Artery Disease
Determinants of Cardiac Risk Factor Modification in Latinos With Coronary Artery Disease
This is an observational study among Latino patients who have coronary artery disease. The goal of the study is to determine the association between having depressive symptoms and the ability to modify one's health behavior.
- Trial name
- NCT00248859
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.