Clinical trials: Clinical Laboratory Techniques
Critical Laboratory Values, Drug Laboratory Interactions
Effect of an Automated Paging System on Response to Critical Laboratory Values
Patients in hospitals may develop serious problems that are detected by blood tests. It is very important for the physicians to be notified of these abnormal blood tests as soon as possible.
- Conditions
- Critical Laboratory Values, Drug Laboratory Interactions, Drug Drug Interactions
- Trial name
- NCT00469924
- Testing
- Real Time Clinical Alerting
- Where
- Canada
- Volunteers
- 271 people
- Sponsor
- Sunnybrook Health Sciences Centre
Caries
Technique for Localization of Caries Associated Bacteria on Tooth Surfaces.
There is a simple laboratory technique for localization of caries associated bacteria on tooth surfaces by taking an impression of the teeth with a material containing sucrose.
- Trial name
- NCT00421577
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Low-Value Care, Costs and Cost Analysis
Optimization of Low-Value Medical Testing Practices in Hospitalized Patients in Argentina
Overuse of laboratory testing in hospitalized patients is a common form of low-value care and may contribute to patient discomfort, unnecessary downstream testing, inefficient use of healthcare resources, and increased costs.
- Conditions
- Low-Value Care, Costs and Cost Analysis, Implementation Science, Public Health
- Trial name
- OPTIMIZAR (NCT07629219)
- Testing
- OPTIMIZAR Multicomponent Diagnostic Stewardship Bundle
- Where
- 8 sites in Argentina
- Volunteers
- 600 people
- Sponsor
- Hospital Italiano de Buenos Aires
Infertility
Comparison Of The Embryoscope Time-Lapse System With Standard Embryo Culture
"Embryoscopes," allow for embryo culture to be performed in an automated incubation system under time lapse photography. Manufacturers of these systems (and investigators who have used these systems) claim that the availability…
- Trial name
- NCT02246309
- Testing
- Embryoscope Time Lapse System, Standard Embryo Culture
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Health Promotion
Caregiver Stress: Interventions to Promote Health and Wellbeing
More and more family members are providing care to their loved ones with prolonged and progressive illnesses. Chronic intense caregiving represents a situation of chronic stress, which takes a toll on one's mental and physical…
- Trial name
- NCT01188070
- Testing
- Usual Care, Psycho-education, Psycho-education plus physical exercise
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Emory University
Covid19
Clinical Study Spartan COVID-19 V2 System
This multicentre prospective study will enroll a sufficient number of patients to afford approximately 60 positives and > 40 negatives (as determined by the SOC - Comparator method) in the United States and/or Canada.
- Trial name
- NCT04575168
- Testing
- Spartan COVID-19 Test
- Where
- 3 sites in United States
- Volunteers
- 81 people
- Sponsor
- Spartan Bioscience Inc.
Bulk-fill Which is Special Type of Resin Composite, Bisphenol A-Glycidyl Methacrylate
Bulk-fill With Different Technique Three-year Clinical Performance
The current study will be intended to evaluate and compare three-year clinical performance of class II bulk-fill resin composite restorations placed with different techniques.
- Trial name
- NCT05861908
- Testing
- Filtek™ Bulk Fill restoration, Heated Filtek™ Bulk Fill restoration, G-aenial™ BULK Injectable restoration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Laboratory Procedure Development and Validation
Specimen Collection Study for Development and Validation of Laboratory Procedures
Biologic samples are necessary for development and validation of laboratory procedures (e.g. novel biological and analytical assays, explant tissue models, validation of specimen collection and transport) to support future…
- Trial name
- NCT01236027
- Testing
- no intervention
- Where
- United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Giant Cell Arteritis, Polymyalgia Rheumatica
Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic
The GCAIO study is an innovative, multimodal research initiative designed to enhance the understanding, diagnosis, and management of giant cell arteritis (GCA) and frequently associated polymyalgia rheumatica (PMR).
- Trial name
- GCAIO (NCT06460142)
- Testing
- Aortic/ cardiac magnetic resonance imaging, Vascular ultrasound, Transorbital Ultrasound
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Correlation of cFDNA During CPB to Laboratories SIRS Parameters and Clinical Outcomes
Measurement of Circulating Cell-free DNA (cfDNA) for Diagnosis and Prognosis of Various Diseases and Evaluation of Tissue Damage
To characterize the changes in circulating cell-free DNA (cfDNA) levels during cardiopulmonary bypass (CPB) and to access their association with outcomes compared to standard scores.
- Trial name
- NCT05094960
- Testing
- Blood samples
- Volunteers
- 71 people
- Sponsor
- Soroka University Medical Center
Inlays
This Trial Will Evaluate the Clinical Performance of Onlay Restorations Fabricated Using Rubber Dam Scanning Techniques.
The purpose of this study will be to evaluate the clinical performance of CAD-CAM onlay restorations fabricated using rubber dam scanning techniques up to 12 months and laboratory investigation of their marginal fit.
- Trial name
- NCT05978440
- Testing
- onlay preparation
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma
Understanding New Cachexia Subtypes Through Observational Epidemiological Research
The UNCOVER study is a longitudinal observational cohort focused on patients at high risk for cancer cachexia. At Kaiser Permanente Northern California, up to 800 individuals with advanced or unresectable non-small cell lung…
- Conditions
- Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma, Advanced Pancreatic Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8
- Trial name
- UNCOVER (NCT07776353)
- Testing
- Biospecimen Collection, Computed Tomography, Electronic health record review
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Kaiser Permanente
Radiation Exposure
Comparison Of Effective Radiation Shielding Between Rampart IC, M1128 Shield vs Conventional Apron And Shields In Clinical Interventional Procedures
Previous studies have documented that orthopedic injuries and musculoskeletal pain are a likely result of wearing heavy leaded aprons.
- Trial name
- RAMPART (NCT05347290)
- Testing
- Rampart IC, M1128, Lead Apron and Ancillary Shield, Rampart IC, M1128 and Lead Apron
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Fertility, Male, Sub-Fertility, Male
Study of the Consumer Use of a New Home Test to Measure Sperm Concentration
The objective of the study is to evaluate the agreement in measurement of sperm concentration in human semen between lay users with TRAK and a recognized reference method.
- Trial name
- NCT02475395
- Testing
- TRAK device
- Where
- 3 sites in United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Sandstone Diagnostics
Diagnostic Techniques and Procedures, Clinical Laboratory Techniques
Clinical Validation of an Artificial Intelligence System for the Interpretation of Laboratory Test Results Combined With a Structured Medical History
This study evaluates a certified artificial intelligence (AI) based software system that automatically interprets laboratory test results in combination with a structured, dynamically generated medical history questionnaire.
- Conditions
- Diagnostic Techniques and Procedures, Clinical Laboratory Techniques, Triage
- Trial name
- LTC-VALID (NCT07810491)
- Testing
- AI-based laboratory result interpretation software
- Where
- 2 sites in Poland
- Volunteers
- 899 people
- Sponsor
- Labplus Sp. z o.o.
Healthy
Testing Performance and Usability of Q300 Device
A data collection clinical study performed on live human spermatozoa samples. Spermatozoa are imaged by QART Q300TM microscopy system. For the feasibility 1st phase of the study, up to 75 donors are expected to participate.
- Trial name
- NCT04901572
- Testing
- QISI device
- Where
- 4 sites in Israel
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- QART Medical
Covid19
Validation of Laboratory Techniques, Strategies, and Types of Samples for Epidemiological Control in the Covid-19 Pandemic
This is a study of validation for diagnostic techniques used on epidemiological control in the COVID-19 pandemic. It will be carried out in accredited public, private and university clinical laboratories of the collaborator…
- Trial name
- NCT04581083
- Testing
- RT-PCR, LAMP, POOL RT-PCR
- Where
- Bolivia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Covid19
Clinical Study Spartan COVID-19 V2 System (Canada Alternate)
This multicentre prospective study will enroll a sufficient number of patients to afford approximately 30 positives and > 30 negatives (as determined by the SOC - Comparator method) in the United States and/or Canada.
- Trial name
- NCT04628208
- Testing
- Spartan COVID-19 v2 System
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- Spartan Bioscience Inc.
Healthy Adults
Validation of NAD+ Measurements for Human Clinical Studies
The purpose of this study is to determine nicotinamide adenine dinucleotide (NAD) levels in healthy adult subjects before and after supplementing with over-the counter nicotinamide riboside (NR) using magnetic resonance…
- Trial name
- NCT07416786
- Testing
- Oral NR Supplementation
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Peripheral Arterial Occlusive Disease
ASA- and Clopidogrel-Responsiveness in Patients With Peripheral Arterial Occlusive Disease and Interventional Procedures
The purpose of the study is to determine the response to aspirin (ASA) and Clopidogrel in patients with peripheral arterial occlusive disease (PAOD) requiring interventional procedures and to investigate if patients with…
- Trial name
- NCT00593762
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Johann Wolfgang Goethe University Hospital