Clinical trials: Clinical Markers
Nasal Defect
Deviation Parameters of Intraorfal Scanning in Capturing Different Intraoral Defects
For all participants, a conventional facial impression will be done using silicone material then poured and scanned using a desktop scanner which represented the control group (Group 1).
- Trial name
- NCT06315621
- Testing
- Scanning using intraoral scanner with markers, Scanning using intraoral scanner without markers, Physical Impression
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Aging, Obesity
Resistance Exercise Training in the Older Population With Obesity
Background: Aging leads to an alteration in the immune response, characterized by a chronic inflammatory state, and a progressive decrease in muscle quantity and quality, a situation that increases in women and in the presence of…
- Trial name
- RETOPO (NCT06367296)
- Testing
- Prolonged resistance exercise training
- Where
- 2 sites in Chile
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Overweight, Risk Behavior
Fasting-mimicking Diet and Longevity Diet, Body Composition and Aging
This study was designed as a large, randomized, controlled clinical trial in a heterogeneous population and is aimed at assessing as a primary objective whether the fasting-mimicking diet alone or in combination with the…
- Conditions
- Overweight, Risk Behavior, Obesity
- Trial name
- NCT05698654
- Testing
- Fasting-mimicking diet (FMD), Longevity Diet (LD) + Fasting-mimicking Diet (FMD)
- Where
- Italy
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Fondazione Valter Longo
Gingivitis, Dental Plaque
Clear Aligner Cleaning: Brushing, Chlorhexidine, and BlueM Effects on Oral Microbial Ecology and Periodontal Indices
This randomized crossover study will assess how three aligner-cleaning methods affect early supragingival oral microbial ecology and periodontal health in adults using clear aligners.
- Trial name
- NCT07307716
- Testing
- Mechanical toothbrushing (fluoride toothpaste), Chlorhexidine mouthwash (0.2%), Oxygen-based cleanser
- Where
- Saudi Arabia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Hemorrhagic Stroke, Acute
Predictive Value of Human Microbiome and Serological Markers for Clinical Outcome of Cerebral Hemorrhage
Objective: To explore the predictive value of characteristic disorder of intestinal flora for clinical prognosis in patients with intracerebral hemorrhage.
- Conditions
- Hemorrhagic Stroke, Acute, Outcomes, Metabolites
- Trial name
- NCT05551923
- Testing
- intestinal flora disturbance
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Pain
CytoQuel: Clinical Documentation on Effects on Chronic Pain, Wellness, and Reduction of Inflammatory Markers
The purpose for this protocol is to perform an open-label parallel-arm clinical study in healthy subjects to evaluate the efficacy of a nutraceutical product on chronic pain, vascular health, inflammation, and overall wellness.
- Trial name
- NCT03690609
- Testing
- CytoQuel
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Discolored Teeth
Effect on Periodontal Markers by Bleaching Intracoronal Technique
OBJECTIVES: The aim of this clinical randomized, double-blind clinical study was to assess the markers levels of RANKL IL-1B and OPGL, involved in the external cervical resorption as a primary outcome, and change color…
- Trial name
- BLEIC (NCT02718183)
- Testing
- Hydrogen Peroxide 35% (Opalescence Endo - Ultradent, USA), carbamide peroxide 37% (Whiteness Superendo, FGM, Brazil).
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
Knee Osteoarthritis
Follow-up of Osteo-articular Biomarkers After Spa Therapy in a Population With Knee Osteoarthritis and Their Correlation With the Clinical Evolution
Spa therapy is used in the treatment of various diseases and mainly osteoarthritis. Knee osteoarthritis is a very common rheumatic disease whose prevalence increases with longer life span and is a public health problem.
- Trial name
- BIOMARTHROSE (NCT04308369)
- Testing
- Blood collection arm
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CHI MONT DE MARSAN ET PAYS DES SOURCES
Traumatic Brain Injury, Major Depressive Disorder
MRI Markers of Feedback Timing During Learning in Individuals with TBI with and Without Clinical Depression
The goal of this proposal is to examine the influence of feedback timing on learning and brain function in individuals with moderate-to-severe traumatic brain injury (TBI), with and without depression.
- Trial name
- NCT05009511
- Testing
- Learning through feedback
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Ischemic Stroke, Acute, Tumor Progression
Predictive Value of Human Microbiome and Serological Markers for Clinical Outcome of AIS With Active Cancer
Explore with active cancer patients with acute ischemic stroke in the human body characteristic microorganism disorder to clinical prognosis of the predictive value of the secondary objective: to observe with active cancer…
- Trial name
- NCT05553990
- Testing
- intestinal flora disturbance
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Diabetes Mellitus, Type 1, Complications
Long Term Vascular Changes in Type 1 Diabetes
The main purpose of this study is to investigate progression of late complications of diabetes during the last ten years in a well characterized cohort of type 1 diabetes with a long duration of the disease, and to define factors…
- Conditions
- Diabetes Mellitus, Type 1, Complications, Coronary Heart Disease
- Trial name
- DM09 (NCT00991575)
- Where
- Norway
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Range of Motion
Evaluation of Activity Levels, Inflammatory Markers, and Overall Wellness.
The purpose for this protocol is to perform a double-blind, randomized, placebo-controlled, parallel-arm clinical study in healthy subjects to evaluate the efficacy of a nutraceutical product on physical and mental energy levels…
- Trial name
- 114-012 (NCT03619265)
- Testing
- Prickly pear juice, Pear-flavored juice
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Chronic Pain, Pain, Chronic
Investigating Biological Targets, Markers, and Intervention for Chronic Pain
This multi-modal methods study will investigate neurophysiological, endocrinological, cognitive, psycho-social-emotional markers of chronic pain, and therapeutic targets using integrative health treatments.
- Conditions
- Chronic Pain, Pain, Chronic, Pain Syndrome, Pain, Neuropathic
- Trial name
- NCT04625504
- Testing
- Mindfulness Based Intervention
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Schizophrenia
Investigation of Neurophysiological Markers, Possibly Specific of Two Subforms of Psychotic Disorders
The current diagnostic criteria for schizophrenia and other psychotic disorders are relatively broad and lack precision. Therefore, distinct diseases may be grouped together under the same diagnostic category, although these…
- Trial name
- NeuroSplitsz (NCT03649581)
- Testing
- compare the two groups of schizophrenic patients, compare the two groups of schizophrenic patients versus volunteers
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Dyslipidemia
Hs-CRP as Clinical Marker of Inflammatory Atherogenic Dyslipidemia
The objective of this proposal is to study the applicability of the hs-CRP assay in the assessment of CV risk in daily clinical conditions where hyperlipidemic population with or without CHD are currently evaluated.
- Trial name
- NCT00169871
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Obesity, Metabolic Syndrome
Genetics of Obesity in Chinese Youngs
The purpose of this study is to explore the pathogenesis and genetic susceptibility of obese subjects,providing a convincing argument for further treatment of obesity and metabolic syndrome.
- Trial name
- GOCY (NCT01084967)
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Genetic Skin Disease, Keratosis Follicularis
Study of Scaling Disorders and Other Inherited Skin Diseases
The purpose of this study is to identify the genes responsible for certain scaling disorders and other inherited skin diseases and to learn about the medical problems they cause.
- Conditions
- Genetic Skin Disease, Keratosis Follicularis, Lamellar Ichthyosis
- Trial name
- NCT00001292
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Arrhythmia Atrial, Atrial Fibrillation
Atrial Fibrillation Research In CATalonia
The AFRICAT study is a prospective, multicenter, population-based study, which aims to create and apply a sequential screening program for atrial fibrillation (AF) in a high-risk population by integrating clinical…
- Conditions
- Arrhythmia Atrial, Atrial Fibrillation, Hypertension, Diabetes Mellitus
- Trial name
- AFRICAT (NCT03188484)
- Where
- 2 sites in Spain
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Survival of Probiotics During GI Transit, GI Symptoms
Acidophilus Pearls Fecal Recovery Study
Commercial probiotics can be delivered in numerous forms. The two most common delivery forms are similar to the two product formats to be tested.
- Trial name
- NCT02001610
- Testing
- Acidophilus pearls, Hard shell gelatin capsules
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Florida
Constipation
Dietary Supplementation Effects on Bowel Movement Frequency and Intestinal Biological Markers in Seniors Presenting Slowed Intestinal Transit
This randomized, double-blind, controlled clinical trial among healthy volunteers with infrequent bowel movements but not severe constipation evaluate the effects of a supplementation in "symbiotic" on intestinal transit of…
- Trial name
- NCT04304170
- Testing
- VES002
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CEN Biotech