Clinical trials: Clinical Pain
Postoperative Pain Management
A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients for Postoperative Pain Treatment in Orthopedic Surgery
This is a multi-center, randomized, double-blind, placebo/active-controlled study. 405 subjects undergoing orthopedic surgery under general anesthesia are planned to be enrolled and randomized into the HSK21542 group, morphine…
- Trial name
- NCT07186426
- Testing
- HSK21542, morphine
- Where
- 2 sites in China
- Volunteers
- 405 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Chronic Low-back Pain
Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Chronic Low Back Pain
This study is being done to test the safety and efficacy of the study drug LY3016859 for the treatment of chronic low back pain.
- Trial name
- NCT04529096
- Testing
- LY3016859
- Where
- 34 sites in United States, Puerto Rico
- Volunteers
- 149 people
- Sponsor
- Eli Lilly and Company
Refractory Angina Pectoris
Extracorporeal Shockwave Therapy for the Treatment of Refractory Angina Pectoris
Low intensity shockwaves have been proven in animal studies to induce local growth of new blood vessels from existing ones. The hypothesis of this study is that shockwave therapy could improve the symptoms of patients with…
- Trial name
- NCT00662727
- Testing
- Cardiac Extracorporeal Shockwave Therapy generator (Cardiospec)
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Medispec
Joint Disease
Post Market Clinical Follow-Up Study Protocol for PROFEMUR® TL Modular Femoral Stems
Sponsor is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) marketed in the European Union (EU) .
- Trial name
- NCT02239783
- Testing
- total hip arthroplasty implant
- Where
- Canada
- Volunteers
- 143 people
- Sponsor
- MicroPort Orthopedics Inc.
Pain, Chronic, Pain, Radiating
Change in Pain and Quality of Life Following SCS for Chronic Pain
Study Title Subject-reported treatment efficacy and procedure satisfaction (steps) study.BURST study- a prospective observational clinical study examining the changes in quality of life and pain following spinal cord stimulation…
- Conditions
- Pain, Chronic, Pain, Radiating, Pain, Back, Pain Syndrome
- Trial name
- BURST (NCT03421951)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- KM Clinical Research Group
Pain
An Observational Study to Investigate Clinical Usefulness of OROS Hydromorphone in Korean Cancer Patients
This study aims to collect clinical information and to examine the usefulness and safety of ORal Osmotic System Hydromorphone in Korean cancer patients.
- Trial name
- NCT01273454
- Testing
- OROS Hydromorphone
- Volunteers
- 648 people
- Sponsor
- Janssen Korea, Ltd., Korea
Coronary Artery Disease, Angina Pectoris
Clinical Utility of an Age, Sex, and Gene Expression Score (ASGES or Corus CAD) in African American Patients.
This is a retrospective study, designed to be conducted at a single-center in the US. The study will conduct a one-time data abstraction from approximately 500 patient medical charts who received Age/Sex/Gene Expression score…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- AACU (NCT02405754)
- Testing
- Corus CAD (ASGES)
- Where
- United States
- Volunteers
- 667 people
- Sponsor
- CardioDx
Chronic Pain
Algovita Spinal Cord Stimulation System Hi-Fi Study
The objective of this study is to obtain post-market clinical outcome data for the Algovita SCS System when used on-label, according to the applicable directions for use, using high fidelity tonic stimulation at either ultra-high…
- Trial name
- NCT03622866
- Testing
- Ultra-high pulse width stimulation, Traditional pulse width stimulation
- Where
- 10 sites in United States
- Volunteers
- 20 people
- Sponsor
- Nuvectra
Neuralgia
To Evaluate the Efficacy and Tolerability of the Use of Vitatonus Dexa Compared to Dexamethasone in Patients With Neuralgia of Various Origins
To evaluate the efficacy and tolerability of Vitatonus Dexa compared with dexamethasone in the signs and symptoms of neuralgia of various origins.
- Trial name
- NCT00944502
- Testing
- Dexamethasone
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Bunker Industria Farmaceutica Ltda.
Cardiac Arrythmias, Unstable Angina
CardioSenseSystem Compared Study Regarding Efficacy and Safety in the Monitoring of ECG
This is a prospective, controlled, comparative clinical trial of a new ECG monitoring system CardioSenseSystem prior CE marking.
- Conditions
- Cardiac Arrythmias, Unstable Angina, Heart Valve Disorders, Disorder of Aorta
- Trial name
- NCT03610529
- Testing
- CardioSenseSystem, Philips Intellivue
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Novosense AB
Menopause
A Clinical Trial to Evaluate the Safety and Efficacy of DR-2041(Synthetic Conjugated Estrogens, A) for Treatment of Vulvovaginal Atrophy
This is a four-arm, randomized, double-blind, parallel group, placebo-controlled study to compare the effects of two doses of DR-2041(Synthetic Conjugated Estrogens, A) Vaginal Cream on vulvovaginal atrophy in postmenopausal…
- Trial name
- NCT00361569
- Testing
- DR-2041a, DR-2041b
- Where
- 97 sites in United States
- Volunteers
- 622 people
- Sponsor
- Duramed Research
Healthy
Study for Comparing The Pharmacokinetics of A Pregabalin Controlled Release Tablet 300mg With Immediate Release Formulation and to Assess the Effect of High Fat Diet in Healthy Male Subjects
The purpose of this study is to: 1. Compare the pharmacokinetics profiles of pregabalin sustained release tablet (300mg) to immediate release capsule(150mg * 2). 2.
- Trial name
- NCT02103686
- Testing
- Lyrica, Experimental drug, High fat meal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Osteoarthritis of the Knee
Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee
The purpose of this trial is to investigate the efficacy and safety of OLT1177 Gel in subjects with moderate to severe pain associated with osteoarthritis of the knee following cessation of pain therapy.
- Trial name
- NCT01768975
- Testing
- OLT1177 Gel
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Olatec Therapeutics, Inc.
Chronic Stable Angina
Evaluating Dose-proportionality of Dilatrend Suspended-Release Capsule
This study is designed to evaluate dose-proportionality of Dilatrend SR 8mg, 16mg, 32mg, 64mg, 128mg in healthy male volunteers.
- Trial name
- NCT01369472
- Testing
- Dilatrend SR capsule
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Chronic Pain
Clinical Study on a Novel Minimally Invasive Posterior Sacroiliac Fusion Device
The PainTEQ study is a prospective, multi-site, prospective, single arm study intended to collect clinical data outcomes data associated with the treatment of sacroiliac disease with the LinQ fusion procedure.
- Trial name
- NCT04423120
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- PainTEQ, LLC
Diabetic Peripheral Neuropathic Pain
Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Diabetic Peripheral Neuropathic Pain
This study is being done to test the safety and efficacy of the study drug LY3016859 for the treatment of diabetic peripheral neuropathic pain.
- Trial name
- NCT04476108
- Testing
- LY3016859
- Where
- 36 sites in United States, Puerto Rico
- Volunteers
- 125 people
- Sponsor
- Eli Lilly and Company
Painful Diabetic Neuropathy
Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Painful Diabetic Neuropathy
The primary objective of the study is to assess the efficacy of eslicarbazepine acetate (ESL) as therapy for patients with painful diabetic neuropathy.
- Trial name
- NCT00980746
- Testing
- Eslicarbazepine acetate
- Volunteers
- 557 people
- Sponsor
- Bial - Portela C S.A.
Back Pain, Acute Pain
Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study
This was an interventional, double-blind, placebo controlled, randomized, single dose, proof-of-concept study. It was a single-center clinical trial.
- Trial name
- NCT04799041
- Testing
- GTX 2/3
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Algenis SpA
Rheumatoid Arthritis
Safety and Effect on Pain and Function According to RAPID-3 of IHL-675A in Patients With Rheumatoid Arthritis
The goal of this randomised, double-blind, placebo-controlled Phase II clinical trial is to assess the safety and effect of of IHL-675A in rheumatoid arthritis patients on pain, and function according to RAPID-3.
- Trial name
- CHAPPII (NCT05942911)
- Testing
- IHL-675A, Cannabidiol, Hydroxychloroquine
- Where
- 10 sites in Australia
- Volunteers
- 20 people
- Sponsor
- Incannex Healthcare Ltd
Coronary Artery Disease
BIOFLOW III Satellite-ELADIS Orsiro Stent System
This registry is a clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT02029092
- Where
- 14 sites in Spain
- Volunteers
- 404 people
- Sponsor
- C.E.M. Biotronik, S.A.