Clinical trials: Clinical Pain
Lumbosacral Radiculopathy
US vs FL-Guided Lumbar Nerve Root Injections
The goal of this clinical trial is to learn if ultrasound-guided nerve root injections work as well as fluoroscopy (X-ray)-guided injections to treat lower back and leg pain caused by irritated nerves (lumbosacral radiculopathy)…
- Trial name
- NCT07627308
- Testing
- Ultrasound-Guided Selective Lumbar Nerve Root Injection, Fluoroscopy-Guided Selective Lumbar Nerve Root Injection
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Tanta University
Neuropathic Pain in Cancer
Phase II Clinical Trial of NPC-06 in Patients With Neuropathic Pain in Cancer
The purpose of this trial is to investigate the efficiency of pain relief and the safety of NPC-06 for the neuropathic pain associated with cancer, in addition to explore the effective concentration of NPC-06.
- Trial name
- NCT03773055
- Testing
- NPC-06
- Where
- Japan
- Volunteers
- 7 people
- Sponsor
- Nobelpharma
Carbohydrate Intolerance
Impact of Two Dietary Interventions on Simple Carbohydrate Intolerance
In this project we want to assess impact of dietary fructose as a simple sugar intolerance on abdominal pain and compare a low FODMAP diet versus an added sugar elimination diet effectiveness on symptoms but also impact on…
- Trial name
- NCT06057376
- Testing
- Low-FODMAP diet group (LFD), Low Sugar diet group (LAS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Facial Neuralgia, Pain
Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain
This study will evaluate the safety and effectiveness of two drugs-dextromethorphan and topiramate-in treating orofacial (mouth and face) pain.
- Conditions
- Facial Neuralgia, Pain, Trigeminal Neuralgia
- Trial name
- NCT00001725
- Testing
- Dextromethorphan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Chronic Knee Pain
Clinical Trial of the MiniStim PNS for Knee Pain- "FLEX" Study
This is a prospective, multi-center, randomized, study in which 300 evaluable subjects will be randomized 1:1 to receive active or delayed therapy with Moments PNS.
- Trial name
- NCT04580732
- Testing
- MiniStim PNS
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- MiniStim LLC
Crowding, Tooth
Evaluation of the Patient Experience With a Surgically-assisted Acceleration Method of Orthodontic Treatment
The duration of orthodontic treatment is one of the exacerbation causes of orthodontic pain. Several methods have been suggested to reduce the duration of orthodontic treatment classified to surgical and non-surgical methods.
- Trial name
- NCT05250921
- Testing
- Corticision, Conventional fixed appliance
- Where
- Syria
- Volunteers
- 52 people
- Sponsor
- Damascus University
Fibromyalgia, Chronic Pain
Cortical Excitability Modulation With ctDCS in Fibromyalgia.
Fibromyalgia is a syndrome characterized by chronic generalized musculoskeletal pain, accompanied by other symptoms such as fatigue, sleep disturbance and depression.
- Trial name
- ctDCS (NCT05963321)
- Testing
- TDCS
- Where
- 2 sites in Brazil
- Volunteers
- 92 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postoperative Pain
Transversus Abdominis Plane Block Versus Paravertebral Block for Post Operative Pain Relief in Open Renal Surgeries
Pain relief after renal surgeries is essential as it may lead to reduction in the incidence of many post operative complications .
- Trial name
- NCT04697420
- Testing
- Thoracic paravertebral block, Transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chemotherapy-induced Polyneuropathy
Clinical Trial With Aconite Pain Oil in Oncology Patients Under Chemotherapy to Prevent CIPN, to Reduce Symptoms and to Improve the Quality of Life of Patients With CIPN
The clinical trial is planned as a prospective, multicentre, blinded, randomised, placebo-controlled, national clinical trial in Germany.
- Trial name
- NCT06186479
- Testing
- Aconite pain oil
- Where
- Germany
- Volunteers
- 350 people
- Sponsor
- WALA Heilmittel GmbH
Mastalgia
A New Treatment Option for Mastalgia
The main objective of this study is to determine the effectiveness of transcutaneous electrical nerve stimulation (TENS) treatment on pain and quality of life in mastalgia, which treatment has not yet reached a consensus.
- Trial name
- NCT06168110
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Ankara University
Thrombosed External Hemorrhoid
Pain Relief for Thrombosed External Haemorrhoids
Thrombosed external haemorrhoids are one of the most frequent anorectal emergencies. They are associated with swelling and intense pain.
- Trial name
- NCT00717782
- Testing
- injection of botulinum toxin, injection of saline
- Volunteers
- 30 people
- Sponsor
- University of Palermo
Chronic Low Back Pain (cLBP)
Integration of Virtual Reality and Traditional Acupuncture: From Education to Clinical Practice.
This research project aims to develop and validate whether a "VR-assisted traditional acupuncture therapy model" provides superior pain relief and functional improvement compared to acupuncture alone.
- Trial name
- NCT07816796
- Testing
- VR-Assisted Acupuncture Group, Traditional Acupuncture Group, Conventional Care / Outcome Assessment Only
- Volunteers
- 90 people
- Sponsor
- China Medical University Hospital
Humans, Young Adults
Analysis of the Effects on Human Tissues After Application of Therapeutic Modalities.
As a therapeutic modality, cryotherapy is highly used for soft tissue damage control during acute and subacute stages. Cryotherapy is able to reduce pain, inflammatory condition, muscle spasm, nerve conduction, metabolic rate…
- Conditions
- Humans, Young Adults, Health
- Trial name
- NCT03414346
- Testing
- Exclusively ice pack, Ice pack added 10% of water, Ice pack added 100% of water
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alessandro Haupenthal
Low Back Pain
Effectiveness of Manual and Instrumental Myofascial Release in Chronic Low Back Pain and the Posture of Practitioners CrossFit®
Background: Chronic low back pain (LBP) can lead to major functional disabilities and force people to take time off work, sports or leisure activities.
- Trial name
- NCT06715761
- Testing
- Myofascial release, Cupping therapy
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- Gabriela Souza de Vasconcelos
OA Knee, OA Knee Pain
Comparison of Medial Knee Pain Between Patients With and Without Preoperative Tibia Vara Underging Mobile-bearing Unicompartmental Knee Arthroplasty
to compared VAS for medial knee pain between oa knee with or without tibia vara following mobile bearing UKA
- Conditions
- OA Knee, OA Knee Pain, Osteoarthritis
- Trial name
- bow leg (NCT07720024)
- Testing
- mobile bearing UKA
- Where
- Thailand
- Volunteers
- 150 people
- Sponsor
- Thammasat University
Analgesia
Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery
Preemptive analgesia can improve postoperative pain management. Ketamine may prevent central sensitization during surgery and result in preemptive analgesia.
- Trial name
- NCT00532662
- Testing
- S(+)-ketamine
- Where
- 2 sites in Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Neck Pain
Study Evaluating the Benefit of Dry Needling for Patients With Neck Pain
The purpose of this study is to determine whether individuals with neck pain will respond favorably to a program of manual therapy, directed at the cervical and thoracic spine (including thrust manipulation), and exercise, in…
- Trial name
- NCT01301170
- Testing
- dry needling
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Integrated Therapy Practice PC
Cancer, Pain
Effentora® in Clinical Practice - a Non-interventional Study to Evaluate Satisfaction and Tolerability
Aim of this non-interventional study is to investigate the tolerability of Effentora® in cancer pain patients with breakthrough pain under real-life conditions in clinical practice.
- Trial name
- ERKENTNIS (NCT01400854)
- Testing
- Effentora®
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Cephalon
Osteoarthritis, Knee, Pain, Joint
Assessment of the Effect of Spa Treatment on Rheumatological Conditions
1. Primary outcome measure: measuring the effect of spa treatment in patients suffering from lower limb osteoarthritis or any other lower limb rheumatological condition.
- Conditions
- Osteoarthritis, Knee, Pain, Joint, Lower Back Pain, Rheumatic Diseases
- Trial name
- CONTREXEVILLE (NCT03538470)
- Testing
- Spa Treatment
- Where
- 4 sites in France
- Volunteers
- 150 people
- Sponsor
- SAEML Contrexéville
Neuropathic Pain
Spinal Magnetic Stimulation in Neuropathic Pain
It involves delivering a train of magnetic pulses, 5 at each time, to the brain. In the present study, we are using the same method to treat severe pain due to nerve conditions.
- Trial name
- NCT00443469
- Testing
- magnetic stimulation, Magnetic Stimulation with tilted coil
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Singapore General Hospital
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