Clinical trials: Clinical Pain
Knee Osteoarthritis
Perineural Dextrose Versus Local Anesthetic Injections in Knee Osteoarthritis
This prospective observational study aims to compare the clinical effectiveness of perineural 5% dextrose injections and perineural local anesthetic injections in patients with symptomatic knee osteoarthritis.
- Trial name
- NCT07381621
- Testing
- Perineural 5% Dextrose Injection, Perineural Local Anesthetic Injection
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ankara Training and Research Hospital
Chronic Neck Pain, Non-specific Neck Pain
Effects of a Multimodal Telerehabilitation Program in Patients With Chronic Non-Specific Neck Pain.
The purpose of this study is to evaluate the clinical results in pain intensity, neck disability, range of motion, endurance deep cervical muscles, forward head position and kinesiophobia through thoracic spine mobility, deep…
- Trial name
- NCT07260955
- Testing
- Thoracic exercise program and education, Thoracic and neck specific exercise program and education
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Universitat Internacional de Catalunya
Insufficient Keratinized Gingiva
Evaluation of the Effectiveness of Different Procedures on Palatinal Wound Healing After Free Gingival Graft Surgery.
This study aimed to help determine the appropriate method to accelerate wound healing at the free gingival graft donor site and to minimize the patient's postoperative complaints.
- Trial name
- NCT06867055
- Testing
- Injectable platelet-rich fibrin (I-PRF), 0.8% hyaluronic acide (HA), control group
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- SEVAL CEYLAN ŞEN
Coronary Heart Disease, Stable Angina Pectoris
Studies of Traditional Chinese Medicine Clinical Efficacy Evaluation Index
The purpose of the trial is to take stable angina pectoris of coronary heart disease (CHD) as examples to build a standard evaluation system for efficacy of traditional Chinese medicine (TCM). 1.
- Trial name
- NCT01502943
- Testing
- Louxiangdan Tongxin granules, Chixiangshen Tongxin granules, Western basis treatment
- Where
- 10 sites in China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Liaoning University of Traditional Chinese Medicine
Kidney Calculi
Study Evaluating the Helical Ureteral Stent
The Boston Scientific Helical Stent is a unique stent designed to improve flexibility and comfort. It is designed to conform more to the shape of the ureter (hollow tube connecting the kidney and the bladder) to ultimately…
- Trial name
- NCT01739725
- Testing
- Stent insertion
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University of British Columbia
Shoulder Impingement, Shoulder Pain
Comparison of Manual Therapy Versus Radial Shock Waves in the Shoulder Pain Treatment
Subacromial syndrome represents the third leading cause of pain in the general population. There is no clear pathophysiological explanation, nor a specific treatment.
- Trial name
- NCT06587399
- Testing
- Manual therapy treatment, Radial shock wave treatment
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- University of Alcala
Pain, Postoperative
Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery
The goal of this clinical trial is to learn if there is a difference in morphine requirements in patients after upper extremity surgeries including shoulder arthroscopy.
- Trial name
- NCT05824832
- Testing
- Interscalene block with the addition of buprenorphine, clonidine, dexamethasone, Interscalene block with buprenorphine alone
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Loyola University
Pain
A Clinical Study of SHR8554 Injection for the Treatment of Pain After Abdominal Surgery.
The primary objective is to evaluate the analgesic efficacy of IV SHR8554 compared with placebo and morphine in patients with acute postoperative pain following abdominal surgery
- Trial name
- NCT04766463
- Testing
- SHR8554 Injection, Morphine
- Where
- China
- Volunteers
- 528 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Neuropathic Pain
Efficacy and Safety of Praga Formulation in the Treatment of Neuropathic Pain
The purpose of this study is to evaluate the efficacy and safety of Praga formulation in the treatment of neuropathic pain.
- Trial name
- NCT04666714
- Testing
- Praga formulation, Pregabalin 75mg, Pregabalin 150mg
- Where
- Brazil
- Volunteers
- 136 people
- Sponsor
- EMS
Premenstrual Syndrome, Mastodynia
Efficacy and Safety of 20 mg (2 Tablets of 10mg)VAC BNO 1095 FCT on Cyclic Mastodynia and PMS
The purpose of this study is to proof the efficacy and safety of 20 mg (2 tablets of 10 mg) VAC BNO 1095 film-coated tablets in patients suffering from cyclic mastodynia and PMS (pre menstrual syndrome).
- Trial name
- NCT01870687
- Testing
- 20mg VAC BNO 1095 FCT
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Bionorica SE
Postoperative Pain, Lumbar Disc Surgery
Efficacy and Safety of Ultrasound-guided Lateral Thoracolumbar Interfascial Plane Block (TLIPB) for Postoperative Pain in Patients Undergoing Herniated Lumbar Disc Surgery
Surgery of the lumbar spine is characterized by diffuse and severe postoperative pain. In recent years, some case reports indicate that the thoracolumbar interfascial plane block (TLIPB) can reduce postoperative pain after spinal…
- Trial name
- NCT03951038
- Testing
- PCIA group, Lateral TLIPB group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Osteoarthritis, Degenerative Joint Disease
Post Marketing Clinical Follow up Study to Evaluate the Performance and Safety of HYALEXO
This trial is a post marketing clinical follow up study, aiming to evaluate the performance and safety of Hyalexo for pain relief in patients suffering from osteoarthritis or degenerative joint diseases.
- Trial name
- NCT05229458
- Volunteers
- 54 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Postoperative Pain, Chronic Pain
A Clinical Trial of a Psycho-educational Intervention to Improve Pain Management After Day Surgery
Evidence indicates that postoperative pain after day surgery is inadequately controlled. Patients have different experiences and knowledge about how to deal with pain, and the need for information and clarification may vary.
- Trial name
- NCT01595035
- Testing
- psychoeducational
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo Metropolitan University
Pain, Chronic, Pain, Postoperative
Efficacy of Pain Neuroscience Education and Pre-anesthetic Assessment in Reducing Levels of Anxiety, Stress and Pain in Patients Undergoing Elective Total Abdominal Hysterectomy (ENAH Study)
Through this quantitative, multivariate factorial experimental parallel randomized clinical trial, the investigators analyzed the effectiveness of pre-anesthetic assessment and pain neuroscience education in reducing anxiety…
- Conditions
- Pain, Chronic, Pain, Postoperative, Anesthesia, Surgery
- Trial name
- NCT05435508
- Testing
- Pain Neuroscience Education, Usual care
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Instituto Neurociencia Del Dolor
Pain
Anti-histamines Promote Electroacupuncture Analgesia: Basic and Clinical Research
Acupuncture has been used in traditional Chinese medicine for around 3,000 years and is increasingly practiced worldwide. The effects of acupuncture in chronic pain have been investigated in many clinical trials.
- Trial name
- NCT03805035
- Testing
- electroacupuncture, antihistamine(low dose) chlorpheniramine (Dexchlorpheniramine maleate), antihistamine(high dose) chlorpheniramine (Dexchlorpheniramine maleate)
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Post Operative Pain Management
Efficacy of Erector Spinae Plane Block Versus Subcostal Transversus Abdominis Plane Block in Laparoscopic Nephrectomy
The investigators hypothesize that erector spinae plane block is better than subcostal transversus abdominis plane block regarding postoperative pain management.
- Trial name
- NCT06670508
- Testing
- Subcostal Transversus Abdominis Plane block, Erector Spinae Plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Neuropathic Pain, Peripheral Neuropathy
Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management
Compare Axon Therapy using transcutaneous magnetic stimulation (tMS) against conventional medical management in treating post-traumatic peripheral neuropathic pain (PTPNP).
- Trial name
- NCT04795635
- Testing
- CMM + Axon Therapy
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- NeuraLace Medical, Inc.
Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries
Effectiveness of Three Oral Devices as Mouthguard in Electroconvulsive Therapy. Randomized Crossover Clinical Trial.
This observer-blind crossover intervention study aims to determine the most effective type of device as oral mouthguard in modified-Electroconvulsive Therapy (m-ECT) comparing three types of devices: standard, prefabricated and…
- Conditions
- Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries, Dental Occlusion, Traumatic
- Trial name
- NCT02678715
- Testing
- Solubrux®, Customized Appliance, Somatics®
- Where
- Spain
- Volunteers
- 4 people
- Sponsor
- Eva Willaert Jiménez-Pajarero
Knee Osteoarthritis
Symptomatic Efficacy of Diacerein in Knee Osteoarthritis
Pain is the main symptom of osteoarthritis that motivates medical visits. Diacerhein has already demonstrated its efficacy in knee and/or hip osteoarthritis.
- Trial name
- NCT00445276
- Testing
- Diacerein
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Laboratoires NEGMA
Chronic Pain
Impact of QoLibri Medical Device on the Consequences of Chronic Pain: a Randomized Controlled Trial
A superiority study evaluating the impact of the QoLibri Software as Medical Device on functional and psychological consequences of chronic pain in primary care patients.
- Trial name
- QoLiDoc (NCT06841276)
- Testing
- QoLibri Digital Therapy
- Where
- France
- Volunteers
- 410 people
- Sponsor
- Novesia
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