Clinical trials: Clinical Pain
Patellofemoral Pain Syndrome
Dosage-dependence of Graded Exercise Therapy in Patients With Patellofemoral Pain Syndrome.
With this study two different therapeutic exercise regimens will be compared in patients with anterior knee pain (patellofemoral pain syndrome, PFPS).
- Trial name
- NCT01290705
- Testing
- High exercise therapy, Low exercise therapy
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology
Knee Osteoarthritis, Knee Arthritis
Pain Management After Adductor Canal Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial sought to evaluate the efficacy of the iPACK block with Adductor Canal Block on postoperative pain, functional recovery and NLR and PLR levels.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Arthropathy, Knee Pain Chronic
- Trial name
- NCT06086483
- Testing
- Ropivacaine 0.2% Injectable Solution, 0.9%sodium chloride
- Where
- Poland
- Volunteers
- 361 people
- Sponsor
- Poznan University of Medical Sciences
Plantar Fasciitis, Chronic, Tibial Nerve
Tibial Nerve Size and Clinical Features in Chronic Plantar Fasciitis
This cross-sectional observational study aims to examine the relationship between tibial nerve cross-sectional area at the tarsal tunnel and plantar fascia thickness, pressure pain threshold, foot posture, and functional status…
- Trial name
- NCT07878273
- Testing
- Pressure Pain Threshold Assessment, Plantar fascia ultrasonographic Assessment, Tibial nerve ultrasonographic assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Tooth, Impacted
Bradykinin Receptors and Pain
This study will examine whether bradykinin receptors are produced at the site of wisdom tooth extraction and if they contribute to the amount of inflammation and pain that follows surgery.
- Trial name
- NCT00083356
- Testing
- Wisdom tooth extraction
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Nursing Research (NINR)
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section: RCT
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT04637386
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Chronic Pain
POP SINGER Randomized Clinical Trial
Conduct a feasibility randomized controlled trial (N = 130, 65 per group) comparing the POPSINGER music therapy (MT) intervention to yoga.
- Trial name
- POP SINGER RCT (NCT07756541)
- Testing
- Yoga, Music Therapy
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University Hospitals Cleveland Medical Center
Osteoarthritis
Transcatheter Arterial Micro-Embolization (TAME) Using Nexsphere-F in Patients With Chronic Pain in Elbow or Wrist
In patients with chronic elbow or wrist pain, the pain is controlled by conventional conservative therapy The pain reduction effect of Nexsphere-F embolization in patients who need additional treatment It is intended to…
- Trial name
- NCT06207851
- Testing
- Transcatheter Arterial Micro-Embolization
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Next Biomedical Co., Ltd.
Knee Osteoarthritis, Biofiller PRP
Evaluation of the Effect of Biofiller PRP Application on Knee Osteoarthritis
The aim of this study is to evaluate the effects of biofiller PRP on function, pain level, and femoral cartilage thickness in knee osteoarthritis: a randomized clinical study
- Conditions
- Knee Osteoarthritis, Biofiller PRP, Femoral Cartilage Thickness
- Trial name
- NCT06946056
- Testing
- Biofiller platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Sickle Cell Disease, Vaso-occlusive Pain Episode
Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease
The goal of this clinical trial is to learn if intravenous citrulline works to treat acute pain in hospitalized patients with sickle cell disease. It will also learn about the safety of intravenous citrulline.
- Trial name
- NCT06635902
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Suvankar Majumdar
COPD
The Prevalence of Chronic Pain in COPD and Its Clinical Implications
This study explores the prevalence of chronic pain in individuals with COPD compared to healthy controls and examines the clinical implications of pain on symptoms associated with COPD, psychological effect and physical activity.
- Trial name
- NCT05366946
- Testing
- Prevalence study
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- West Park Healthcare Centre
Submucosal Resection of the Nasal Septum (SMR)
Four vs. Ten Local Anesthetic Injections for SMR
Submucosal resection of the nasal septum (SMR) could be performed under local anesthetic infiltration performed through ten injections in addition to general anesthesia which was associated with less postoperative pain and…
- Trial name
- NCT02463370
- Testing
- suprazygomatic maxillary area infiltration, non-suprazygomatic maxillary area infiltration
- Where
- Lebanon
- Volunteers
- 120 people
- Sponsor
- Makassed General Hospital
Hysteroscopy
Pericervical Analgesia Versus Analesia With Nitrous Oxide (N2O) in Outpatien Operative Hysteroscopy With Miniresector
This research will have the aim of evaluating and comparing the effectiveness of two methods (analgesia with nitrous oxide and pericervical analgesia, excluding the use of paracervical block due to the increased risk of…
- Trial name
- NCT06092541
- Testing
- Intervention Group: pericervical anesthesia, Nitroux Oxide anesthesia
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ospedale degli Infermi di Biella
Cancer Pain
A Randomized Controlled Trial of a Web-based Platform for Cancer Pain Management
Malignant tumors are one of the major public health problems in China, and cancer pain is a common symptom in tumor patients, affecting the quality of life.
- Trial name
- NCT06663956
- Testing
- a patient self-reporting applet
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Neuropathy, Neuropathy;Peripheral
Clinical Efficacy of the Erchonia EVRL for Providing Temporary Relief of Idiopathic Peripheral Neuropathy Foot Pain
The purpose of this clinical study is to determine the effectiveness of the Erchonia® EVRL™, manufactured by Erchonia Corporation (the Company), in providing prescription home use application for temporary relief of idiopathic…
- Trial name
- NCT06912646
- Testing
- Erchonia® EVRL™
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Erchonia Corporation
Postoperative Pain
Influence of Early Coronal Flaring Upon Postoperative Pain After Root Canal Treatment
The aim of this clinical study is to evaluate the influence of early coronal flaring upon postoperative pain following root canal treatment in a single session approach.
- Trial name
- flaring (NCT05169879)
- Testing
- coronal flaring, Non coronal flaring
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Pain, Chronic Pain
A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care
The purpose of this study is to evaluate the impact of genetic testing on healthcare decisions and patient outcomes for patients suffering from pain, cardiovascular problems, Arthritis, Type II Diabetes, and/or Mental Health…
- Conditions
- Pain, Chronic Pain, Mental Disorders, Cardiovascular Diseases
- Trial name
- REVOLUTION (NCT02487888)
- Testing
- Unblinded to Genetic Testing Results, Blinded to Genetic Testing Results
- Where
- 31 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- Proove Bioscience, Inc.
Postoperative Complications
Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?
the investigators aim is to investigate and explore the effect 10 mg morphine added to local anesthetics in serratus anterior plane block for post mastectomy pain management after modified radical mastectomy in patients with…
- Trial name
- NCT02962024
- Testing
- Morphine Sulfate, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fatma Adel El sherif,MD
Proximal Femur Fracture
Postoperative Pain Relieve for Patients Undergoing Surgical Treatment of Femoral Fracture
The aim of the study is to investigate postoperative pain relief for patients undergoing surgical treatment of proximal femoral fracture using intrathecal administration of morphine.
- Trial name
- NCT05920642
- Testing
- Intrathecal morphine administration, Parenteral administration of analgesics
- Where
- Czechia
- Volunteers
- 82 people
- Sponsor
- University Hospital Ostrava
Spinal; Nerve Root, Pain, Pelvic Pain
Quality of Life and Pain Changes Due to DRG Stimulation for Chronic Pain
ACTIVE study- a prospective observational clinical study examining the changes in quality of life and pain following dorsal root ganglion stimulation for the treatment of chronic intractable pelvic and lower limb pain.
- Conditions
- Spinal; Nerve Root, Pain, Pelvic Pain, Regional Pain Syndrome, Chronic Pain Syndrome
- Trial name
- ACTIVE (NCT03417973)
- Testing
- dorsal root ganglion neuromodulation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- KM Clinical Research Group
Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic Pulp
Effect of 1% Melatonin Gel Versus Calcium Hydroxide as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic Pulp.
To compare the effect of 1% melatonin gel versus calcium hydroxide as intra canal medication in necrotic mandibular premolars on: Intensity of postoperative pain. Bacterial load reduction. Periapical (MMP-9) level.
- Trial name
- RCT (NCT07495605)
- Testing
- 1% melatonin gel, Calcium Hydroxide (Ca(OH)2)
- Volunteers
- 50 people
- Sponsor
- Cairo University
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