Clinical trials: Clinical Pain
ERAS, Surgery
Effect of Modified ERAS Protocol on Clinical Outcomes in Pediatric Patients With Appendectomy
Acute appendicitis is the most common abdominal emergency with more than 15 million cases reported worldwide. Although appendectomy is considered a safe surgical procedure, the incidence of complications is up to 10%.
- Conditions
- ERAS, Surgery, Appendicitis
- Trial name
- NCT05962320
- Testing
- Education and counselling, Avoiding the use of nasogastric catheters, drains and urinary catheters, Stimulation of intestinal motility in the postoperative period
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Karadeniz Technical University
Postoperative Complications, Postoperative Pain
A Clinical Follow-up Study on the Efficacy of Thumbtack Needle for Postoperative Sleep and Recovery Treatment
To understand the impact of thumb-tack needle therapy on postoperative sleep and recovery in patients who have undergone general anesthesia, and to explore the clinical significance of thumb-tack needle therapy in improving…
- Conditions
- Postoperative Complications, Postoperative Pain, Acupuncture
- Trial name
- NCT06757023
- Where
- 2 sites in China
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Labor Pain
Epidural Placement Using Handheld Ultrasound Device vs. Traditional Landmark Palpation
Ultrasound is widely in uses for vascular, nerve block and sometimes neuraxial block. The purpose of the study is to evaluate the impact of a handheld ultrasound device on the time to complete labor epidural placement and success…
- Trial name
- NCT04020042
- Testing
- Ultrasound image guidance, Landmark palpation
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Texas Southwestern Medical Center
Abnormal Labial Frenum Frenectomy, Frenectomy
Pain After Diode Laser Frenectomy in Children
This prospective single-group clinical study aims to evaluate postoperative pain following diode laser-assisted frenectomy in pediatric patients and to assess the agreement between different pediatric pain assessment scales.
- Trial name
- PED-FREN (NCT07706023)
- Testing
- Diode Laser-Assisted Frenectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Neuropathic Pain
The Pharmacokinetics of GLA5PR Tablet According to the Renal Function
To evauate pharmacokinetics of GLA5PR tablet according to the renal function
- Trial name
- NCT03963362
- Testing
- GLA5PR tablet 75 mg, GLA5PR tablet 150 mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Headache Disorders, Primary, Headache Disorders
Amylin-Induced Migraine Attacks Without Aura
Pramlintide is a peptide analogue of human amylin which is a vasoactive signaling molecule involved in the pathogenesis of migraine.
- Conditions
- Headache Disorders, Primary, Headache Disorders, Brain Diseases, Nervous System Diseases
- Trial name
- NCT07340788
- Testing
- Amylin
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Knee Osteoarthritis
Wearable LITUS Device for Osteoarthritis of the Knee: a Randomized Double-Blind Placebo-Controlled Trial
The purpose of this study is to measure the effectiveness of a wearable therapeutic ultrasound device in patients with stage I and stage II knee osteoarthritis.
- Trial name
- NCT02083861
- Testing
- Sam Ultrasonic Diathermy Device
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- ZetrOZ, Inc.
Acupuncture
Evaluation of the Effect of Acupuncture on Hand Pain, Functional Deficits and Health Related Quality of Life in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is a systemic inflammatory disease characterized by functional disability and pain. Although acupuncture is widely used, western acupuncture studies on RA show no conclusive positive result.
- Trial name
- NCT02553005
- Testing
- Acupuncture
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- University of Coimbra
Hemophilia
Movement Visualization in Patients With Hemophilic Arthropathy
Background. The recurrence of hemarthrosis in patients with hemophilia favors the development of an intra-articular, degenerative and progressive lesion (hemophilic arthropathy).
- Trial name
- NCT04237766
- Testing
- Experimental group
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Real Fundación Victoria Eugenia
Neck Pain
Evaluation of the Efficacy of Cervical Pillows in Subjects With Non-specific Chronic Neck Pain
This randomized controlled with cross-over trial aims to investigate the efficacy of a cervical pillow (the "Viscospring PostuRite" made by SOFF-ART S.r.l.
- Trial name
- NCT03165669
- Testing
- Viscospring PostuRite - "medium" model, Education
- Where
- 2 sites in Italy
- Volunteers
- 70 people
- Sponsor
- University of Bologna
Scoliosis Idiopathic, Fascia
Exercise Effects on Fascia, Low Back Pain, and Function in Scoliosis
The use of various muscle energy techniques to address fascial restrictions, in addition to three-dimensional correction within scoliosis-specific exercise approaches, suggests that these exercises may have different effects on…
- Conditions
- Scoliosis Idiopathic, Fascia, Low Back Pain
- Trial name
- NCT07418983
- Testing
- Scientific Exercise Approach to Scoliosis (SEAS) Exercises, Functional Individual Therapy of Scoliosis Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Hacettepe University
Osteoarthritis of the Knee
Apitox, Honeybee Venom Treatment for Osteoarthritis Pain and Inflammation
The study will evaluate Apitox, pure honeybee venom as a treatment for pain and inflammation of osteoarthritis of the knee.
- Trial name
- HBV (NCT00949754)
- Testing
- honeybee venom (Apitoxin (Korea) Apitox (USA))
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Apimeds, Inc.
Pain
A Multicenter Efficacy Study of a Diclofenac+Menthol Gel in Subjects With Ankle Sprain
This Phase III pivotal efficacy study will assess efficacy and onset of pain relief of MFC51123 gel vs. placebo and MFC51123 gel vs.
- Trial name
- NCT02100670
- Testing
- 1% diclofenac sodium plus 3% menthol, 1% diclofenac sodium plus 0.09% menthol, 3% menthol
- Where
- 3 sites in Germany
- Volunteers
- 385 people
- Sponsor
- GlaxoSmithKline
Chronic Pancreatitis
Pain and Chronic Pancreatitis - Clinical End Experimental Studies
The aim of the study is to investigate the effect of pregabalin in pain resulting from chronic pancreatitis. The effect will be investigated by means of questionnaires concerning the daily experience of pain and the general…
- Trial name
- CPP (NCT00755573)
- Testing
- Pregabalin
- Where
- 2 sites in Denmark, Netherlands
- Volunteers
- 64 people
- Sponsor
- Aalborg University Hospital
Postoperative Pain, Fear
Designing Animated Movie for Preoperative Period
Background: Using visual materials is effective in education to decrease children's pre-operative fear and post-operative pain. Children, especially those aged between 6 and 12 years, are interested in technology.
- Conditions
- Postoperative Pain, Fear, Surgery, Pain
- Trial name
- NCT04176822
- Testing
- Educational animated movie group, Documentary movie group
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ege University
Pain, Chronic, Pain, Acute
Real-World Experience of Athletes Treated With SAM
Low-intensity continuous ultrasound (LICUS) is an FDA-approved bio regenerative technology, applied with a wearable device (SAM, Zetroz Systems LLC) for daily use.
- Conditions
- Pain, Chronic, Pain, Acute, Sport Injury, Soft Tissue Injuries
- Trial name
- NCT04177537
- Testing
- Low Intensity Continuous Ultrasound
- Volunteers
- 15 people
- Sponsor
- ZetrOZ, Inc.
Endometriosis
Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain.
The primary objective of this study is to demonstrate the efficacy and safety of linzagolix administered orally once daily for 3 months at a dose of 75 mg alone or of 200 mg in combination with add-back hormone replacement…
- Trial name
- NCT03992846
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 71 sites in United States, Austria and 8 more
- Volunteers
- 486 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Idiopathic Scoliosis
Effect of Global Postural Re-education in Idiopathic Scoliosis
In North America, children and adolescents with idiopathic scoliosis (IS) are rarely referred for a rehabilitation program whereas the European guidelines stated that scientific evidences concerning scoliosis specific…
- Trial name
- NCT03663088
- Testing
- GPR-A, GPR-B
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital
Impacted Third Molar Tooth
EFFICACY OF ICE PACK THERAPY AFTER IMPACTED THIRD MOLAR SURGERY
this study evaluates the effect of cold application after impacted third molar extractions. Patients have bilateral impacted third molar tooth included in this study.
- Trial name
- NCT03261869
- Testing
- Cold application
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Baskent University
Primary Dysmenorrhea
Efficacy and Safety of DEH113 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea
The purpose of this study if to evaluate the efficacy and safety of DEH113 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea.
- Trial name
- LIBERTÀ (NCT06268054)
- Testing
- DEH113
- Volunteers
- 78 people
- Sponsor
- EMS
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