Clinical trials: Clinical Pain
Patellofemoral Pain Syndrome
Clinical Subgroups in Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) is a multifactorial pathology characterized by diffuse retropatellar and peripatellar pain in the knee joint, exacerbated by overloading activities on the patellofemoral joint.
- Trial name
- NCT03201133
- Testing
- Neuromuscular evaluation
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Federal University of Rio Grande do Sul
Retinopathy of Prematurity, Pain
The Effect of Eyemasks on Neonatal Stress Following Dilated Retinal Examination
Although screening exams for retinopathy of prematurity (ROP) prevent blindness they are physiologically stressful for infants. The investigators postulate that photosensitivity during mydriasis contributes to post-examination…
- Conditions
- Retinopathy of Prematurity, Pain, Premature Infant, Retinal Disease
- Trial name
- MASK-ROP (NCT03824782)
- Testing
- Phototherapy Mask
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- Sunnybrook Health Sciences Centre
Dental Anxiety, Pain
Virtual Reality Distraction During Restorative Dental Treatment
This split-mouth randomized clinical trial will evaluate the effect of virtual reality (VR) distraction on pain perception, anxiety, physiological responses, and patient experience during local anaesthesia administration and…
- Trial name
- NCT07738718
- Testing
- Virtual Reality Headset, Standard Dental Treatment
- Where
- Saudi Arabia
- Volunteers
- 13 people
- Sponsor
- Qassim University
Chronic Prostatitis, Chronic Pelvic Pain Syndrome
Clinical Efficacy of Roxithromycin in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Roxithromycin is effective in the treatment of intracellular organisms, including chlamydia and mycoplasma, and exhibits anti-inflammatory and immunomodulatory effects on respiratory diseases.
- Trial name
- NCT01843946
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Low Back Pain
Transpubic Symphysis Reset for Treatment of Low Back Pain
To verify the efficacy of transpubic symphysis reset therapy for low back pain, and provide support for the clinical application of this treatment.
- Trial name
- NCT02906540
- Testing
- Transpubic symphysis reset therapy group, Physiotherapy group
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Appendicitis
EHR-based Decision Support for Pediatric Acute Abdominal Pain in Emergency Care
Although appendicitis is the most common surgical emergency in children, its diagnosis remains a challenge and thus, emergency department (ED) providers increasingly rely on computed tomography to distinguish appendicitis from…
- Trial name
- Appy-CDS (NCT02633735)
- Testing
- Appy CDS
- Where
- 2 sites in United States
- Volunteers
- 5,940 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Dental Crowding, Malocclusion
Clear Aligners With Two Different Change Schedules vs Traditional Braces for People With Crowded Lower Front Teeth
The goal of this clinical trial was to compare two clear aligner treatment plans with traditional braces for treating crowded lower front teeth in adults. Clear aligners were removable plastic trays.
- Trial name
- NCT07821723
- Testing
- Clear aligner, 0.25 mm per step, Clear aligner, 0.35 mm per step, Conventional fixed orthodontic appliance
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Ain Shams University
Hip Osteoarthritis, Chronic Pain
Comparative Study Between Steroid Plus Anesthetic Block and CRF in Participants With Hip Osteoarthritis
This will be a prospective, multi-center, double-blinded, randomized study designed to compare the efficacy of Conventional Radiofrequency (CRF) and the anesthetic block of the anterior sensory branches to the hip to control pain…
- Trial name
- NCT04876859
- Testing
- CRF of anterior sensitive branches to the hip, Anesthetic block with steroid injection of anterior sensitive branches to the hip
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Brasilia
Pain After Abdominal Surgery
Phase II Clinical Study of the Efficacy and Safety of HSK55718 in the Treatment of Abdominal Postoperative Pain
A multicenter, randomized, double-blind, placebo-controlled, and positive-controlled phase II clinical trial was conducted to evaluate the efficacy and safety of HSK55718 injection for postoperative analgesia in patients…
- Trial name
- NCT07491146
- Testing
- Low dose HSK55718, Medium Dose HSK55718, High dose HSK55718
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Yingyong Zhou,MD,PhD
Pain
Efficacy of Yogurt Containing BB12 in Subjects With GI Symptoms
The purpose of this study is to determine if probiotics bacteria, specifically bifidobacterium lactis (BB12) improve gastrointestinal symptoms in subjects with functional gastrointestinal symptoms (i.e., non-patients…
- Trial name
- NCT00618488
- Testing
- Probiotic BB12 - Bifidobacterium lactis
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of North Carolina
Knee Osteoarthritis, Cartilage Damage
Clinical Study of Pain Reduction by Peri-arthroscopic PRP Application in Knee Degeneration
The purpose of this study is to investigate reduction of pain, gain of function and improvement of life quality by intraoperative applied platelet- rich- plasma ( PRP ) during knee arthroscopy for degeneration and osteoarthritis…
- Conditions
- Knee Osteoarthritis, Cartilage Damage, Meniscal Tear
- Trial name
- PRP-Bochum (NCT02189408)
- Testing
- Platelet rich plasma
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Ruhr University of Bochum
Postoperative Pain, Edema
Bromelain and Escin in the Reduction of Postoperative Sequelae in Periodontal and Implant Surgery
A randomized clinical trial will be performed in parallel, placebo controlled, triple-blind to evaluate the effectiveness of the association Bromelina and Horse-chestnut (titrated in escin) (Noflogo®, Mavenpharma s.r.l., Rome…
- Conditions
- Postoperative Pain, Edema, Swelling Lips & Face
- Trial name
- NCT04657874
- Testing
- Bromelains and Escin Oral Tablet
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Uterine Fibroids, Adenomyosis
Effect of Addition of Steroids on Duration of Analgesia
The purpose of the study is to investigate the differences in post-procedural pain scores and narcotic use among patients who receive a Superior Hypogastric Nerve Block (SHNB) with and without corticosteroid performed as part of…
- Trial name
- NCT04126824
- Testing
- Triamcinolone, Bupivacaine, Iohexol contrast
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Endometriosis, Dysmenorrhea
Effect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant Therapy
The goal of this clinical trial is to investigate the effect of propolis administration on dysmenorrhea in endometriosis patient.
- Trial name
- NCT05770297
- Testing
- Propolis
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Adhesive Capsulitis, Shoulder Pain
Ultrasound Guided Shoulder Intra-Articular Ozone Injection Versus Pulsed Radiofrequency Application for Shoulder Adhesive Capsulitis
The aim of this study is to evaluate the efficacy of the ultrasound guided shoulder intra-articular Ozone injection versus pulsed radiofrequency application in patients with shoulder adhesive capsulitis.
- Trial name
- NCT04724317
- Testing
- Steroid Group, Ozone Group, PRF Group
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ahmed Foula
Myocardial Infarction, Myocardial Ischemia
Pain Perception is Attenuated in Patients With Painless Myocardial Infarction
To explore whether reduced systemic pain perception in response to painful stimuli and personality pain related variables characterizes silent MI patients.
- Trial name
- NCT00192790
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Postoperative Pain
Oral Gabapentin Versus Placebo for Treatment of Postoperative Pain Following Photorefractive Keratectomy
The purpose of this study is to determine the effectiveness of an oral medication called gabapentin in reducing pain after Photorefractive Keratectomy (PRK) eye surgery and to assess the frequency of use of rescue medication…
- Trial name
- NCT00793910
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Chronic Pain, Central Sensitisation
Clinical Trial on Deprescribing Associated With a Psychoeducational Program Using Virtual Reality for Patients With Chronic Pain and Central Sensitization
This clinical trial evaluates the effectiveness of the REDOCVR program, an interdisciplinary, psychoeducational intervention designed to support deprescribing of chronic pain medications in primary care.
- Conditions
- Chronic Pain, Central Sensitisation, Opioid-Related Disorders, Patient Empowerment
- Trial name
- REDOCVR_AC (NCT06964360)
- Testing
- REDOCVR Psychoeducational Program, Standard Educational Materials
- Where
- 4 sites in Spain
- Volunteers
- 174 people
- Sponsor
- Badalona Serveis Assistencials
Post Operative Pain
The Effectiveness of Local Infiltration Technique in Adult Tonsillectomy
Tonsillectomy is commonly associated with postoperative pain. The modified pre-incision infiltration of anesthetic mixture combined with general anesthesia was shown to decrease post-tonsillectomy pain in children.
- Trial name
- NCT03806335
- Testing
- Infiltration, General anesthesia
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Peripheral Venous Catheterization, Ultrasonography
Patient Experience in Peripheral Venipuncture With and Without Ultrasound
Randomized clinical trial to compare the patient's experience after peripheral venipuncture catheterization using the conventional technique (vein visualization and palpation) versus ultrasound-guided venous puncture.
- Conditions
- Peripheral Venous Catheterization, Ultrasonography, Pain
- Trial name
- PERCEPT (NCT04853290)
- Testing
- Ultrasound-guided peripheral venipuncture, Conventional peripheral venipuncture
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
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