Clinical trials: Clinical Pain
Root Canal Infection
Evaluation of Post Operative Pain Following Reciprocating and Rotary Heat-treated NiTi Instrumentation of Root Canals: a Randomized Controlled Clinical Trial
The present clinical evaluation was planned for comparing the post-operative pain incidence in maxillary premolar teeth with acute irreversible pulpitis treated by recently introduced heat treated TruNatomy TM and other widely…
- Trial name
- NCT04655105
- Testing
- root canal rotary files
- Where
- India
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Tamil Nadu Dr.M.G.R.Medical University
Patellofemoral Pain Syndrome, Vascular Occlusion
Muscle Training With and Without Vascular Occlusion of Women With Patellofemoral Pain Syndrome: A Random Clinical Trial
Introduction: The treatment of Patellofemoral Pain Syndrome (PFPS) uses the strengthening of the knee and hip muscles. Studies propose the use of partial vascular occlusion (OVP) of the quadriceps muscle to increase muscle…
- Trial name
- NCT04478422
- Testing
- Muscle strengthening with vascular occlusion, Conventional muscle strengthening
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Christiane Macedo
Chronic Migraine, Headache, Overuse Headache Medication
Cannabidiol 133mg + Cannabigerol 66mg + Tetrahydrocannabinol 4mg Vs Placebo As Adjuvant Treatment in Chronic Migraine -
To evaluate the effect of the cannabidiol (CBD) + cannabigerol (CBG) + tetrahydrocannabinol (THC) up to 133/66/4mg daily versus placebo as adjuvant treatment in chronic migraine (CM) patients under preventive treatment at a…
- Trial name
- CAMTREA (NCT04989413)
- Testing
- Cannabidiol + Cannabigerol + Tetrahydrocannabinol 133/66/4mg
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Hospital Israelita Albert Einstein
Degenerative Disc Disease, Herniated Disc
Bone Graft Materials Observational Registry
A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and "real world" use of approved and commercially available bone graft substitutes, autograft and allograft.
- Conditions
- Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis
- Trial name
- APPROACH-001 (NCT00974623)
- Testing
- Bone graft substitute, autograft or allograft
- Where
- 14 sites in United States, Hungary and 1 more
- Volunteers
- 329 people
- Sponsor
- Baxter Healthcare Corporation
Osteo Arthritis Knee, Pain, Joint
Efficacy of Cannabidiol in Knee Osteoarthritis
Painful symptomatic osteoarthritis (OA) of the knee is a very common disease, especially in older people (lifetime prevalence 9.5%). Current systemic pharmacological treatment options are limited.
- Trial name
- NCT04607603
- Testing
- Cannabidiol Oral Product
- Where
- Austria
- Volunteers
- 86 people
- Sponsor
- Medical University of Vienna
Low Back Pain
Effect of Lumbar Stabilization Exercises and Circular Dances in Chronic Non Specific Low Back Pain
Supervised exercises are the first line therapy for patients with chronic low back pain. The lumbar segmental stabilization (LSE) is a specific training for the muscles of the lumbar spine, which aims to improve neuromuscular…
- Trial name
- NCT02807090
- Testing
- Lumbar Stabilization Exercise, Circular dance
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo General Hospital
Lumbar Spinal Stenosis
Dynamic Stabilization for Lumbar Spinal Stenosis With Stabilimax NZ® Dynamic Spine Stabilization System
The purpose of this trial is to assess whether the Stabilimax NZ® is at least as safe and effective as the control therapy of fusion in patients receiving decompression surgery for the treatment of clinically symptomatic spinal…
- Trial name
- NCT00529997
- Testing
- Stabilimax NZ® Dynamic Spine Stabilization System
- Where
- 19 sites in United States
- Volunteers
- 480 people
- Sponsor
- Applied Spine Technologies
Cervicalgia
Effectiveness of a Self-rehabilitation Program
The prevalence of non-specific neck pain is 12.1 / 1000 patients / year. Their support is most often based on analgesics combined with physical therapy.
- Trial name
- NCT02549274
- Testing
- self-rehabilitation + physiotherapy, physiotherapy
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Retreatment
Effect of Different Apex Locators on Postoperative Pain in Endodontic Retreatment of Single-Rooted Teeth: Prospective Randomized Clinical Study
Nonsurgical endodontic retreatment is a vital procedure that promotes periapical healing by eliminating previous root canal fillings, necrotic tissue, and residual microorganisms, thanks to the comprehensive cleaning of the root…
- Trial name
- NCT06964490
- Testing
- determination of working length
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ipek Eraslan Akyuz
Myofascial Trigger Point Pain, Myofascial Pain
Effects of Release and Ischemic Pressure of Trigger Points on Neck Pain. A Crossover, Controlled and Randomized Trial.
The aim of the study is to compare two manual therapy techniques. By testing if the Pressure Release of Myofascial Trigger Points technique (PRM) is more effective in treating Myofascial Trigger Points present in the upper…
- Conditions
- Myofascial Trigger Point Pain, Myofascial Pain, Myofascial Pain Syndrome, Neck Pain
- Trial name
- NCT04546490
- Testing
- Pressure Release technique, Ischemic pressure technique
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Quadratus Lumborum Block, Iliohypogastric/Ilioinguinal Nerve Block
Comparison of Ultrasound-guided Quadratus Lumborum Block and Iliohypogastric/Ilioinguinal Nerve Block for Postoperative Pain Management in Patients Undergoing Cesarean Section
The purpose of this study is to compare the analgesic effect of ultrasound-guided quadratus lumborum block and iliohypogastric/ilioinguinal nerve block for postoperative pain management in patients undergoing cesarean section.
- Conditions
- Quadratus Lumborum Block, Iliohypogastric/Ilioinguinal Nerve Block, Cesarean Section
- Trial name
- NCT04822870
- Testing
- quadratus lumborum block, iliohypogastric/ilioinguinal nerve block, epidural analgesia
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Peking University People's Hospital
Joint Pain
Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion & Joint Discomfort in Healthy Subjects
A Randomized, Double-Blind, Placebo-controlled, Parallel Design Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion \& Joint Discomfort in Healthy Subjects
- Trial name
- NCT05212259
- Testing
- Collagen type II (40 mg/day), Collagen type II (80mg/day), Collagen type II (120 mg/day)
- Where
- 10 sites in India
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Romania Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01593059
- Where
- 4 sites in Romania
- Volunteers
- 13 people
- Sponsor
- Biotronik Vertriebs-GmbH
Endometriosis
TUC3PII-01_TU2670 Phase IIa Clinical Study
This Protocol for TU2670 is to investigate the efficacy, safety, pharmacokinetics (PK), and pharmacodynamics (PD) of multiple doses of TU2670 in subjects with moderate to severe endometriosis-associated pain.
- Trial name
- NCT05138562
- Testing
- Active Comparator: TU2670 320mg, Active Comparator: TU2670 240mg, Active Comparator: TU2670 120mg
- Where
- 40 sites in Czechia, Italy and 3 more
- Volunteers
- 86 people
- Sponsor
- TiumBio Co., Ltd.
Low Back Pain
Efficacy of the Electronic Acupuncture Shoes: A Clinical Trial for Chronic Low Back Pain
This randomized , double-blind, parallel-arm clinical trial was designed to study the efficacy and safety of the "Electronic Acupuncture Shoes" treatment on chronic low back pain patients.
- Trial name
- EAS (NCT02468297)
- Testing
- Electronic Acupunture Shoes, Ibuprofen
- Volunteers
- 60 people
- Sponsor
- Chen Yu Sheng
Neoplasms, Pain
Assessment of Cancer Pain in Emergency Department in Traditional Chinese Medicine
Pain control is a common and serious problem in cancer patients. Although WHO has developed a three-stage model of cancer pain management, 80% cancer patients still suffer moderate to severe pain in their daily life.
- Trial name
- NCT02116218
- Testing
- acupuncture, Vaccaria seed
- Where
- Taiwan
- Sponsor
- Changhua Christian Hospital
Trochanteric Bursitis
Core Resistance and Lateral Hip Pain
Although the middle gluteal muscle is an important stabilizer of the pelvis, no relationship has yet been described between the Great Trochanteric Pain Syndrome (GTPS) and the resistance of the core muscles.
- Trial name
- GTPS (NCT05662579)
- Testing
- Exercises
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Universidade Estadual de Londrina
Fibromyalgia
Clinical Outcomes After Dry Needling on Cervical Muscles, and Quality of Life, in Patients With Fibromyalgia Syndrome.
Objectives: The purpose of the current randomized clinical trial is to compare the effectiveness of dry needling versus myofascial release therapy on myofascial trigger points (MTrPs) in cervical muscles, quality of life…
- Trial name
- NCT03015662
- Testing
- Dry Needling Therapy, Myofascial Release Therapy
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Universidad de Almeria
Ankle Fracture
Ankle Fracture Tourniquet Utilization
Lower extremity tourniquet utilization remains a controversial practice during the operative fixation of rotational ankle fractures and is often left to surgeon discretion.
- Trial name
- NCT06863688
- Testing
- Tourniquet, No Tourniquet
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alex Demers
Leg Ulcers
Biatain Ibu vs. Biatain in Painful Chronic Venous Leg Ulcers
The objective of this investigation is to demonstrate the effectiveness and safety of Biatain Ibu non-adhesive foam dressing compared to Biatain non-adhesive foam dressing.
- Trial name
- NCT00627094
- Testing
- Biatain, Biatain Ibu
- Where
- 13 sites in Denmark, France and 2 more
- Volunteers
- 120 people
- Sponsor
- Coloplast A/S
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