Clinical trials: Clinical Pain
Local Anaesthetic, Dental Anxiety
Effect of a Vibration System on Pain Reduction During Injection of Local Dental Anaesthesia in Children
The study assesses the effect of a new vibration system on pain reduction during the injection of local anesthesia. Children undergoing dental treatment are allocated to two groups; one receiving the Buzz, a vibration system and…
- Trial name
- NCT03953001
- Testing
- Adminstration Technique using Buzzy external distractor, 2% Lidocaine with 1:50,000 epinephrine, Topical Anesthetic
- Where
- Saudi Arabia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Coronary Artery Diseases
BIOFLOW III Satellite-Italy Orsiro Stent System
Clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES). 500 subjects will be enrolled in this registry.
- Trial name
- NCT02028728
- Where
- 18 sites in Italy
- Volunteers
- 609 people
- Sponsor
- Biotronik Italia S.p.A.
Pelvic Pain
Effects of Non-ablative Radiofrequency on Female Genito-pelvic Pain Disorder
The goal of this randomized clinical trial is to verify the response of genito-pelvic pain disorders in women associated with inability to penetrate to the treatment with non-ablative radiofrequency.
- Trial name
- Pelvic Pain (NCT06303609)
- Testing
- nonablative radiofrequency, Vaginal dilator
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Centro de Atenção ao Assoalho Pélvico
Pain Measurement, Chronic Pain
Evaluation of Chronic Postsurgical Pain Risk in Patients Undergoing CIED Implantation Using an AID Support System
Chronic postsurgical pain (CPSP) remains a significant clinical and public health challenge despite major advances in surgical and anesthetic techniques.
- Conditions
- Pain Measurement, Chronic Pain, Cardiac Implantable Electrical Devices, Neuropathic Pain
- Trial name
- PAIN-AID (NCT07322900)
- Volunteers
- 180 people
- Sponsor
- Istanbul University - Cerrahpasa
Shoulder Pain
Effectiveness of Immersive Virtual Reality on Biomarkers and Clinical and Clinimetric Variables in Patients With Persistent Shoulder Pain
Shoulder pain is one of the primary reasons for seeking physiotherapy care. The high prevalence of rotator cuff-related shoulder pain underscores the need for research into novel treatment approaches that may enhance the clinical…
- Trial name
- SHOULDERVR (NCT06795464)
- Testing
- Immersive Virtual Reality, Exercise
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad Francisco de Vitoria
Carpal Tunnel Syndrome
Very Low Frequency Magnetic Fields Versus the Supplement "Xinepa" in the Treatment of the Carpal Tunnel Syndrome
The purpose of the study is to determine the effectiveness of the treatment with very low frequency magnetic fields (ELF) on the reduction of pain and the relief of the associated signs such as sensitivity disorders that affect…
- Trial name
- NCT02891512
- Testing
- ELF, Xinepa®
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- University of Roma La Sapienza
Joint Disease
Post Market Clinical Follow-up Study Protocol for DYNASTY® BioFoam® Acetabular Components
Sponsor is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) components marketed in the European Union (EU) .
- Trial name
- NCT02149667
- Testing
- total hip arthroplasty implant
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- MicroPort Orthopedics Inc.
Major Depression, Pain
Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder
Patients with major depressive disorder (MDD) commonly have many gastrointestinal complaints. Gastrointestinal pain is classified into 2 categories: visceral and somatic pain.
- Conditions
- Major Depression, Pain, Abdominal Pain
- Trial name
- NCT00209807
- Testing
- escitalopram, Reboxetine, No intervention
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Headache, Covid19
The Effect of Ganglion Sphenopalatine Block Versus Placebo on Persistent Headache Following COVID-19 Infection
The purpose of this study is to evaluate the effect of the ganglion sphenopalatine block (SPG block) on persistent headache following acute COVID-19 infection.
- Conditions
- Headache, Covid19, Sphenopalatine Ganglion Block, Persistent Headache Following COVID-19
- Trial name
- NCT04636034
- Testing
- Sphenopalatine Ganglion Block with Local Anesthetic
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Non Specific Chronic Low Back Pain
Comparing Graston Technique and Diacutaneous Fibrolysis for Pain, Disability, and Quality of Life in Patients With Non-Specific Low Back Pain
This randomized clinical trial compared Graston Technique (GT) and Diacutaneous Fibrolysis (DF) in 30 patients with non-specific low back pain.
- Trial name
- GT & DF (NCT07836439)
- Testing
- Graston Technique, Diacutaneous Fibrolysis
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Management and Technology Sialkot Pakistan
Joint Discomfort, Wellbeing
Assessing the Potential for Improved Joint Health and Wellbeing by Providing a Whole Salmon Oil With Undenatured Type II Collagen Compared to Type II Collagen Alone
This study evaluates the combination of NT-II® salmon undenatured type II collagen with OmeGo® salmon oil in adults who regularly experience knee discomfort.
- Conditions
- Joint Discomfort, Wellbeing, Quality of Life
- Trial name
- NCT07875101
- Testing
- Undenatured collagen, Whole salmon oil
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA
Pelvic Floor Disorders, Urinary Incontinence
Effectiveness of Hypopressive Exercises Versus Pelvic-perineal Physiotherapy
Introduction: Hypopressive Exercises are included within a method of physiotherapy which was created with the purpose of strengthening the deep muscles of the abdomen without damaging ligamentous and muscular structures of the…
- Conditions
- Pelvic Floor Disorders, Urinary Incontinence, Fecal Incontinence, Pelvic Pain
- Trial name
- HEPFD (NCT02259712)
- Testing
- Hypopressive exercises, Therapeutic education., Pelvic-perineal physiotherapy
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- University of Alcala
Orthodontic Appliance Complication
Control of Pain From Braces With Patient Advice Sheets
To compare the analgesic property of acupressure with NSAIDs (Ibuprofen) in controlling pain following orthodontic treatment. This will be achieved by assessing the effectiveness of acupressure in controlling pain and discomfort…
- Trial name
- COPPAS (NCT03159520)
- Testing
- Advice sheet
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- University of Dundee
Postoperative Pain, Breast Cancer
Comparison of Erector Spinae Plane Block With Serratus Anterior Plane Block for Breast Surgery
Breast cancer is by far the world's most common cancer among women and the most common cause of female death from cancer worldwide. It's worldwide incidence is 43.4 in 100.000 while in Egypt is 48.8 in 100.000.
- Trial name
- NCT03579524
- Testing
- Erector Spinae Plane Block, Serratus Anterior Plane Block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Fayoum University Hospital
Dysmenorrhea
Multi-center Clinical Trials of Sanjie Analgesic Capsule in Treating Endometriosis
It is a multi-center, double -blind, placebo -controlled, randomized post-marketing study in Chinese subjects with endometriosis-associated pain to assess treatment effect and safety in the subjects treated with Sanjie Analgesic…
- Trial name
- NCT02031523
- Testing
- Sanjie analgesic capsule
- Where
- 14 sites in China
- Volunteers
- 400 people
- Sponsor
- Jiangsu Kanion Pharmaceutical Co., Ltd
Manual; Rotation, Obturation
Assessment of Clinical & Radiographic Efficiency of Manual & Pediatric Rotary Systems in Primary Root Canal Preparation
Manual files used for the pulpectomy of primary teeth have some disadvantages such as time wastage and the occurrence of iatrogenic errors compared to rotary systems.
- Conditions
- Manual; Rotation, Obturation, Post Operative Pain
- Trial name
- NCT05619796
- Testing
- pulpectomy procedure, Post-operative Cone Beam Computed Tomography, Post-operative pain assessment
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Endometriosis
A Clinical Trial to Evaluate Efficacy and Safety of Elagolix Tablets in Women With Moderate or Severe Endometriosis-associated Pain
This is a phase 3, multicenter, double-blind, placebo-controlled, randomized study to evaluate the efficacy and safety of elagolix tablets versus placebo in premenopausal women with moderate or severe endometriosis-associated…
- Trial name
- NCT06076486
- Testing
- Elagolix
- Where
- China
- Volunteers
- 202 people
- Sponsor
- Nanjing Chia-tai Tianqing Pharmaceutical
Apical Periodontitis, Post Operative Pain, Acute
Post-operative Pain and Apical Healing After Root Canal (re)Treatment With Laser-activated Irrigation Versus Sonic or no Activation
When a tooth's nerve dies, inflammation can develop at the tip of the tooth's root. Root canal treatment is carried out to allow this inflammation to heal.
- Trial name
- NCT07883486
- Testing
- sonically activated irrigation, laser activated irrigation, conventional needle irrigation
- Where
- 2 sites in Belgium
- Volunteers
- 183 people
- Sponsor
- University Ghent
Peripheral Neuralgia, Chronic Pain
Clinical Study Of a Micro-Implantable Pulse Generator For The Treatment of Peripheral Neuropathic Pain
This post market study is being conducted to document the comparative effectiveness and safety of peripheral nerve stimulation plus conventional medical management versus conventional medical management alone in the treatment of…
- Trial name
- COMFORT (NCT05287373)
- Testing
- Nalu Neurostimulation System for PNS, conventional medical management
- Where
- 13 sites in United States
- Volunteers
- 89 people
- Sponsor
- Nalu Medical, Inc.
Cancer Pain
Gene Transfer for Cancer Pain
The primary purpose of this study is to examine the safety of NP2 (a nonreplicating HSV-based vector expressing enkephalin) in patients with cancer pain. The secondary purpose is to evaluate efficacy.
- Trial name
- NCT00804076
- Testing
- NP2
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Diamyd Inc
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