Clinical trials: Clinical Presentation
Acute Respiratory Infections, Febrile Illnesses
The Fever Clinic Acute Respiratory Cohort
This prospective cohort study aims to characterize the natural progression and outcomes of acute respiratory infections among patients presenting to fever clinics.
- Conditions
- Acute Respiratory Infections, Febrile Illnesses, Community-acquired Pneumonia, Viral Respiratory Tract Infections
- Trial name
- FACTS (NCT07278700)
- Testing
- No intervention involved
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Fudan University
Sepsis
CLEAR Sepsis Clinical Study
To investigate the relationship between initial ClearSight™ derived hemodynamic parameters and outcomes (death, ongoing organ dysfunction or delayed ICU admission) in patients with acute infection and possible sepsis, with a…
- Trial name
- CLEAR Sepsis (NCT03231956)
- Testing
- ClearSight™ / EV1000NI Clinical Platform
- Where
- 5 sites in United States
- Volunteers
- 182 people
- Sponsor
- Edwards Lifesciences
Ischemic Stroke
Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention With Trevo
The purpose of the study is to evaluate the hypothesis that Trevo thrombectomy plus medical management leads to superior clinical outcomes at 90 days as compared to medical management alone in appropriately selected subjects…
- Trial name
- DAWN (NCT02142283)
- Testing
- Trevo Thrombectomy Procedure, Medical Management
- Where
- 32 sites in United States, Australia and 3 more
- Volunteers
- 206 people
- Sponsor
- Stryker Neurovascular
Allergic Rhinoconjunctivitis
Clinical Trial With Subcutaneous Immunotherapy in Depot Presentation in Patients With Allergic Rhinoconjunctivitis Sensitized to House Dust Mites
The aim of the study is to evaluate the safety and tolerability of subcutaneous immunotherapy (SCIT) with House Dust Mite (HDM) extract in patients with rhinoconjunctivitis with or without associated mild asthma and sensitized to…
- Trial name
- NCT02881879
- Testing
- Allergovac depot DPT/DF (50:50)
- Where
- 5 sites in Spain
- Volunteers
- 43 people
- Sponsor
- Roxall Medicina España S.A
COVID-19
Clinical Outcomes of paTients pREsenting to HArare COVID-19 CenTer of Excellence With SARS-CoV-2 Infection
In order to influence COVID-19 treatment guidelines, evidence on disease progression and clinical outcomes of hospitalized COVID-19 patients, particularly those receiving innovative COVID-19 medications in an African setting is…
- Trial name
- TREAT (NCT05529771)
- Where
- Zimbabwe
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Bladder Cancer
Clinical Evaluation of the miR Sentinel BCa™ Test to Diagnose Bladder Cancer in Hematuria Patients
The purpose of the study is to establish the clinical performance and utility of the miR Sentinel™ BCa Test, a urine exosome-based diagnostic test, as an aid in diagnosing bladder cancer.
- Trial name
- NCT04155359
- Where
- United States
- Volunteers
- 444 people
- Sponsor
- miR Scientific LLC
Chronic Shoulder Pain
Effects of Hypertonic Dextrose Water Injection for Supraspinatus Tendinosis Patients
Using hypertonic dextrose water for chronic supraspinatus tendinosis and using ultrasound as assessment tool to evaluate the effect of intervention.
- Trial name
- NCT03000205
- Testing
- hypertonic dextrose water, Normal saline and Lidocaine.
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
COVID-19 Pneumonia
Clinical Presentations and Outcomes of Patients With Covid-19 Pneumonia
This study aims at determining clinical presentations and outcomes of patients with covid-19 pneumonia and also follow up of patients for up to 6 months to detect possibility of post covid fibrosis
- Trial name
- NCT05092555
- Testing
- Nasopharyngeal swap for Reverse transcription polymerase chain reaction
- Volunteers
- 200 people
- Sponsor
- Sohag University
Multiple Rib Fractures, Isolated Blunt Thoracic Trauma
GNRI and PNI for Predicting Short-Term Outcomes in Older Adults With Multiple Rib Fractures
This prospective observational cohort study will evaluate whether the Geriatric Nutritional Risk Index (GNRI) and Prognostic Nutritional Index (PNI) can predict short-term clinical outcomes in adults aged 65 years or older with…
- Trial name
- NCT07823712
- Where
- Turkey (Türkiye)
- Volunteers
- 294 people
- Sponsor
- Ankara Etlik City Hospital
Fuchs' Corneal Endothelial Dystrophy (FCED)
A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED)
This is a Phase 1/2 prospective, randomized, double-masked, and vehicle-controlled trial in two parts to evaluate the safety, tolerability, and efficacy of elamipretide topical ophthalmic solution in patients with Fuchs' Corneal…
- Trial name
- SPIFD-101 (NCT02653391)
- Testing
- Part A Elamipretide 1.0% Ophthalmic Solution, Part B Elamipretide 3.0% Ophthalmic Solution
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Stealth BioTherapeutics Inc.
Dizziness, Vertigo
Validating a Clinical Decision Support Tool for Stratifying Stroke Risk for Dizziness/Vertigo
This study aims to validate a machine learning model that stratifies the risk of stroke in patients who present to the emergency department with dizziness or vertigo.
- Trial name
- NCT06010550
- Testing
- Magnetic resonance imaging
- Volunteers
- 600 people
- Sponsor
- Chiayi Christian Hospital
Pneumonia
Accuracy of Clinical and Diagnostic Studies for Pneumonia in Children
Pneumonia continues to be a leading cause of death in children under five years of age worldwide. Many studies have evaluated clinical signs and symptoms that may predict pneumonia.
- Trial name
- NCT03630380
- Testing
- Clinical History, Physical Exam Findings, Laboratory Findings
- Where
- Nepal
- Volunteers
- 1,000 people
- Sponsor
- Patan Academy of Health Sciences
Melioidosis, Head and Neck Infection
Clinical Presentation of Melioidosis in Head and Neck Region
Melioidosis in head and neck was observed including clinical presentation, diagnosis with titer, and result of treatment.
- Trial name
- NCT03048513
- Testing
- Patient who presented with melioidosis in head and neck
- Where
- Thailand
- Volunteers
- 48 people
- Sponsor
- Khon Kaen University
Polycystic Ovary Syndrome
Clinical and Biochemical Presentation of Polycystic Ovary Syndrome in Different Age Group
To study the clinical and biochemical characteristics women with polycystic ovary syndrome (PCOS) in different aged groups.
- Trial name
- NCT01350895
- Where
- Taiwan
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Meniere Disease, Vertigo
Safety of APSLXR in Patients Presenting Vertigo of Vestibular Origin or Meniere's Disease
The purpose of this study is to evaluate the safety of APSLXR in participants with Meniere's disease or other Verigo of vestibular origin. Pharmacokinetics will also be evaluated in a small group.
- Conditions
- Meniere Disease, Vertigo, Vertigo Vestibular
- Trial name
- NCT04674735
- Testing
- APSLXR
- Sponsor
- Apsen Farmaceutica S.A.
Endometriosis
Impact of Ziwig Endotest® on the Management of Patients With Clinical Symptoms of Endometriosis Inconsistent With Their Imaging Work-up
The goal of this study is to evaluate the impact of Ziiwg Endotest on patient management decisions before and after the test. The main questions it aims to answer are: Does the test reduce the intention and number of…
- Trial name
- ENDOBEST (NCT06794424)
- Testing
- Ziwig Endotest®
- Where
- France
- Volunteers
- 2,503 people
- Sponsor
- ZIWIG
Coccidioidomycosis
Efficacy Study of Fluconazole to Treat Coccidioidomycosis Pneumonia (Valley Fever)
This is a Phase IV randomized, double-blinded, placebo-controlled study in 1000 individuals aged 18 years or older, with community acquired pneumonia (CAP) who meet all eligibility criteria in endemic regions.
- Trial name
- NCT02663674
- Testing
- Fluconazole
- Where
- 9 sites in United States
- Volunteers
- 72 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cervical Pseudarthrosis
Diagnostic Interest of Bone Tomoscintigraphy in the Search for Cervical Pseudarthrosis
Cervical pseudarthrosis is a classic complication and a challenge for challenge for spine surgeons. The rate of pseudarthrosis can range from 3 to 15%, and depend greatly on the patient, the approach the number of levels operated…
- Trial name
- BOSCAR (NCT07140432)
- Testing
- Bone scintigraphy
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Blood Pressure
Clinical Evaluation of the Performance of Bionet Sphygmomanometer Modules Based on Protocol Presented by the International Organization for Standardization
According to INTERNATIONAL STANDARD (hereafter ISO) blood pressure (BP) monitor clinical evaluation protocol (ISO 81060-2:2018, Non-invasive sphygmomanometers- Part2: Clinical investigation of intermittent automated measurement…
- Trial name
- NCT06609486
- Testing
- Blood pressure measurement group
- Where
- South Korea
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hoon-Ki Park
Acute Coronary Syndrome, Clinical Decision Support System
Clinical Decision Support System to Define 30 Day Adverse Clinical Events for Emergency Department Acute Coronary Syndromes
Acute coronary syndromes are among main complains for patients presenting to emergency department. Risk classification systems are used to classify patients to appropriate risks and help physicians manage diagnosis strategies and…
- Trial name
- NCT03286491
- Testing
- Further cardiac imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Turkish Ministry of Health Izmir Teaching Hospital