Clinical trials: Clinical Presentation
Appendicitis Acute, Acute Abdomen in Children
The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary Care
BACKGROUND Acute appendicitis (AA) in an early stage is difficult to distinguish from other (self-limiting) causes of acute abdominal pain (e.g.
- Trial name
- ISAAK (NCT06762275)
- Testing
- Diagnostic strategy
- Where
- Netherlands
- Volunteers
- 566 people
- Sponsor
- University Medical Center Groningen
Peripheral Arterial Disease, Claudication
ILLUMENATE EU Randomized Clinical Trial
This is a prospective, randomized, multi-center, single-blind study to demonstrate the safety and effectiveness of the CVI Paclitaxel-coated percutaneous transluminal angioplasty (PTA) balloon versus bare PTA balloon for the…
- Trial name
- EU RCT (NCT01858363)
- Testing
- CVI Paclitaxel-coated Percutaneous Transluminal Angioplasty Balloon Catheter, Bare Percutaneous Transluminal Angioplasty Balloon Catheter
- Where
- Germany
- Volunteers
- 294 people
- Sponsor
- Spectranetics Corporation
Antiphospholipid Syndrome
Longitudinal Study of the Clinical and Haematological Cause of Women With Antiphospholipid Antibodies.
This study is being done to see if there are any long term health related issues in women with APA and recurrent miscarriages.
- Trial name
- NCT00180817
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Imperial College London
Cancer of Prostate
Clinical Evaluation of the 'ExoDx Prostate IntelliScore' (EPI)
The purpose of this research study is investigate a new and validated urine test which predicts the likelihood of high grade prostate cancer on an initial prostate biopsy The current protocol has two objectives; one is to further…
- Trial name
- NCT03031418
- Testing
- ExoDx Prostate Intelliscore
- Where
- 18 sites in United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Exosome Diagnostics, Inc.
Case-report, Diagnosis
Diagnosis and Clinical Presentation of Iliac Graft-Enteric Fistula: A Case Report
Abstract Introduction: Aorto-enteric fistula (AEF) is a life-threatening complication arising from abnormal connections between the gastrointestinal tract and major arteries.
- Conditions
- Case-report, Diagnosis, Digestive System Fistula, Gastrointestinal Hemorrhage
- Trial name
- NCT06553105
- Testing
- ct scan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Golestan University of Medical sciences
Sepsis, Systemic Inflammatory Response Syndrome
Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?
The aim of this project is to test the utility of The Gene Z device (as of 2018 Gene Z no longer being used), now using In-Dx and other rapid identification techniques that the investigators have developed in the lab on…
- Conditions
- Sepsis, Systemic Inflammatory Response Syndrome, Infection Mixed, Infection, Bacterial
- Trial name
- NCT01904188
- Testing
- Gene Z or other rapid diagnostic techniques developed in our lab (as of 2018 not using Gene Z - now using In-Dx along with other developed techniquesregularly)
- Where
- 2 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Michigan State University
Osteoarthritis
To Study Generic Diclofenac Sodium Topical Gel 1% in the Treatment of Osteoarthritis of the Knee (Degenerative Joint Disease Presented as Joint Pain, Stiffness, Swelling and Restricted Motion).
This is a Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multiple-Site Clinical Study to Evaluate the Therapeutic Equivalence of Diclofenac Sodium Gel, 1% (Glenmark Pharmaceuticals Ltd) to Voltaren® Gel…
- Trial name
- NCT02596451
- Testing
- Diclofenac Sodium gel, 1%, Voltaren® Gel
- Where
- 44 sites in United States
- Volunteers
- 1,164 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
SARS-CoV Infection, COVID-19
Malaysian COVID-19 Anosmia Study (Phase 2) - A Nationwide Multicentre Case-Control Study
The Malaysian COVID-19 Anosmia Study is a nationwide multicentre observational study to investigate the prevalence and characteristics of olfactory and gustatory/taste disturbances in COVID-19 infection in Malaysia, and to…
- Conditions
- SARS-CoV Infection, COVID-19, Anosmia, Dysgeusia
- Trial name
- NCT04384042
- Testing
- Patient-Reported Online Questionnaire on Olfactory & Taste Disturbances
- Where
- 14 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Sultanah Bahiyah
Anaplasmosis, Tick-borne Disease
Human Anaplasmosis in Eastern France
Anaplasmosis is a tick-borne transmitted infection. Its clinical expression include fever, cytopenia and hepatitis.This infection was initially described in United States. In Europe, its epidemiology is not well known.
- Conditions
- Anaplasmosis, Tick-borne Disease, Ehrlichia
- Trial name
- NCT01013636
- Testing
- Blood sampling
- Where
- 12 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Stroke, Dizziness
Impact of a Magnetic Resonance Imaging (MRI) Scanner Exclusively Dedicated to Emergency in the Clinical Management of Patients Presenting With Diplopia or Dizziness
IRM-DU is a prospective observational single center study conducted in an emergency department to evaluate the impact of a MRI scanner exclusively dedicated to emergency in the clinical management of patients presenting with…
- Conditions
- Stroke, Dizziness, Diplopia, MRI
- Trial name
- IRM-DU (NCT03660852)
- Where
- France
- Volunteers
- 119 people
- Sponsor
- University Hospital, Strasbourg, France
Posttraumatic Stress Disorder, Sexual Assault
RCT for Innovating Stress-related eHealth
The Randomized Control Trial for Innovating Stress-related eHealth (RISE) Study tests the hypotheses that a highly promising digital therapeutic (RISE Guide) targeting anxiety sensitivity (AS) will be acceptable to women sexual…
- Conditions
- Posttraumatic Stress Disorder, Sexual Assault, Pain
- Trial name
- RISE (NCT05305235)
- Testing
- RISE Guide, Relaxation Control
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Status Epilepticus
Status Epilepticus in Men and Women: Clinical Presentation, Management, and Outcomes
Sex-specific differences in neurological emergencies such as Status epilepticus (SE) remain understudied despite growing recognition of gender disparities in medicine.
- Trial name
- NCT07443241
- Volunteers
- 779 people
- Sponsor
- University Hospital Marburg
Coma
Comparison Between GCS and FOUR Scores
The goal of this observational study is to compare the predictive utility of the Full Outline of Unresponsiveness (FOUR) Score and the Glasgow Coma Scale (GCS) Score in determining outcomes among patients with altered mental…
- Trial name
- GCS/FOUR (NCT06703619)
- Where
- Iraq
- Volunteers
- 240 people
- Sponsor
- Al-Nahrain University
COVID-19 Respiratory Infection
Post-COVID-19 Pneumo-hematocele
Introduction. As the COVID-19 pandemic has continued, an increasing number of long-term complications are emerging. Recently, the appearance of characteristic pulmonary lesions has been noted, being described as post COVID-19…
- Trial name
- PHC (NCT05067881)
- Testing
- Pulmonary resection
- Where
- Mexico
- Volunteers
- 37 people
- Sponsor
- Hospital General Ajusco Medio
Acute Coronary Syndrome, Myocardium; Injury
Acute Myocardial Infarction: Prognostic and Therapeutic Evaluation
AMIPE is both a retrospective and prospective study which was designed in order to collect data of patients with acute coronary syndromes and myocardial injury and to improve the knowledge about these conditions.
- Trial name
- AMIPE (NCT03883711)
- Testing
- Database
- Where
- 3 sites in Italy
- Volunteers
- 11,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Acute Ischemic Stroke, Ischemic Stroke
Impact of Presenting Symptoms on Treatment Time and Outcomes in Acute Ischemic Stroke
This observational study aims to understand how the specific symptoms a person experiences at the start of an acute ischemic stroke affect how quickly they receive treatment and how well they recover.
- Conditions
- Acute Ischemic Stroke, Ischemic Stroke, Stroke
- Trial name
- NCT07750847
- Volunteers
- 120 people
- Sponsor
- Assiut University
Breech Presentation at Term
Clinical Hypnosis Before External Cephalic Version (ECV)
Does clinical hypnosis or neuro-linguistic programming improve the success rate of external cephalic version?
- Trial name
- NCT01564004
- Testing
- Clinical hypnosis or neuro-linguistic programming
- Where
- Germany
- Volunteers
- 716 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Infection
Recognition of Serious Infections in the Elderly
The aim of this diagnostic accuracy study is to develop a clinical prediction rule based on signs, symptoms, patient characteristics and blood tests, to be used in ambulatory care to help physicians safely rule out a serious…
- Trial name
- ROSIE (NCT04516187)
- Testing
- signs and symptoms, blood tests
- Where
- 12 sites in Belgium
- Volunteers
- 493 people
- Sponsor
- KU Leuven
Surgical Technique, Implant Surface
Clinical and Radiographic Assessment of a Novel Wedge Shape Implant Placed in Edentulous Narrow Ridges
The aim is to clinically and radiographically assess a novel wedge implant placed in narrow ridges. 60 wedge implants (Rex Implants, Columbus, OH, USA) will be placed using Piezosurgery® following either a bone consumption (n=30)…
- Trial name
- NCT06178536
- Testing
- Bone Consumption, Bone expansion
- Where
- Lebanon
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Christian Makary
Skin Cancer, Complication
Complications and Recurrences After Mohs Micrographic Surgery and Slow Mohs
Mohs micro-graphic surgery (Mohs) is a tissue-sparing, surgical treatment for different types of skin cancer (e.g. basal cell carcinoma, squamous cell carcinoma, lentigo maligna (melanoma).
- Conditions
- Skin Cancer, Complication, Complication of Surgical Procedure, Complication,Postoperative
- Trial name
- NCT06014619
- Testing
- Mohs surgery, Slow Mohs surgery
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Maastricht University Medical Center