Clinical trials: Clinical Presentations
Infectious Encephalitis
Management of Tick-borne Encephalitis
In this retrospective cohort study of patients with tick-borne encephalitis (TBE), potential differences in the clinical presentation at admission and diagnostic and therapeutic management of patients with TBE initially referred…
- Trial name
- NCT06593249
- Testing
- No Intervention: Observational Cohort
- Where
- Slovenia
- Volunteers
- 318 people
- Sponsor
- University Medical Centre Ljubljana
Pulmonary Embolism, Venous Thromboembolism
Prognostic Value of 2026 AHA/ACC Clinical Categorization in Acute Pulmonary Embolism Patients Presenting to the Emergency Department
Background: The 2026 American Heart Association/American College of Cardiology (AHA/ACC) Pulmonary Embolism Guideline (Creager et al., Circulation 2026) introduced a novel five-category (A-E) clinical classification system with…
- Conditions
- Pulmonary Embolism, Venous Thromboembolism, Acute Pulmonary Embolism
- Trial name
- APEX-2026 (NCT07805616)
- Testing
- 2026 AHA/ACC Clinical Risk Categorization
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Subjects Presenting With Normal or With Ocular Pathology
Clinical Validation of New OCT System
To demonstrate clinical substantial equivalence of DRI OCT-1 as comparable to the commercially available Cirrus
- Trial name
- NCT01809704
- Where
- 3 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Acute Ischemic Stroke, Ischemic Stroke
Impact of Presenting Symptoms on Treatment Time and Outcomes in Acute Ischemic Stroke
This observational study aims to understand how the specific symptoms a person experiences at the start of an acute ischemic stroke affect how quickly they receive treatment and how well they recover.
- Conditions
- Acute Ischemic Stroke, Ischemic Stroke, Stroke
- Trial name
- NCT07750847
- Volunteers
- 120 people
- Sponsor
- Assiut University
Acute Myocardial Infarction
Acute Myocardial Infarction in Native Versus Non-native Young Population in Saudi Arabia
A retrospective study collecting the data of young patients admitted with diagnosis of Acute Myocardial Infarction.
- Trial name
- YAMI (NCT04427046)
- Where
- Saudi Arabia
- Volunteers
- 600 people
- Sponsor
- Saud Al Babtain Cardiac Center
Myocardial Oxygenation Imbalance, Myocardial Infarction
Clinical Presentation and Outcomes in Patients at Risk of Type II Myocardial InfarctioN in the emerGency Department.
Type 2 myocardial infarction has been reported in the Universal Definition of Myocardial Infarction for more than 10 years and most studies resulted in a high mortality rate.
- Trial name
- COMING (NCT03953651)
- Testing
- Follow-up
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Hospices Civils de Lyon
Overdose, Drug, Drug Use
ASSIST: A Surveillance Study of Illicit Substance Toxicity
There is a drug-related death crisis in Scotland. This study aims to collaborate with Public Health Scotland in order to assess the feasibility of introducing a surveillance system to the Emergency Department to highlight illicit…
- Conditions
- Overdose, Drug, Drug Use, Drug Abuse, Drug Toxicity
- Trial name
- ASSIST (NCT05329142)
- Testing
- Surplus sample toxicology analysis
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- NHS Greater Glasgow and Clyde
Chronic Obstructive Pulmonary Disease
Clinical Presentation and Outcome of COPD Patients With Acute Exacerbation Attending Sohag University Hospital
Chronic obstructive pulmonary disease (COPD) is a worldwide public health challenge because of high prevalence and related disability and mortality (1).
- Trial name
- NCT06684353
- Volunteers
- 200 people
- Sponsor
- Sohag University
Chagas' Disease (Chronic) With Other Organ Involvement
Lower Urinary Tract Dysfunction in Chronic Chagas' Disease : Clinical and Urodynamic Presentation
Chagas disease is one of the most neglected vector-borne infectious disease worldwide. The first decades following the discovery of the pathology drove an international research enthusiasm, mainly concentrated on understanding…
- Trial name
- NCT03189056
- Testing
- Chagas serology, Creatinina, Urodynamic exploration
- Where
- Bolivia
- Volunteers
- 152 people
- Sponsor
- Institut de Recherche pour le Developpement
Allergic Rhinoconjunctivitis
Clinical Trial With Subcutaneous Immunotherapy in Depot Presentation in Patients With Allergic Rhinoconjunctivitis Sensitized to House Dust Mites
The aim of the study is to evaluate the safety and tolerability of subcutaneous immunotherapy (SCIT) with House Dust Mite (HDM) extract in patients with rhinoconjunctivitis with or without associated mild asthma and sensitized to…
- Trial name
- NCT02881879
- Testing
- Allergovac depot DPT/DF (50:50)
- Where
- 5 sites in Spain
- Volunteers
- 43 people
- Sponsor
- Roxall Medicina España S.A
Dystonia, Parkinsonism
Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders
The purposes of this study are to identify persons with rapid-onset dystonia-parkinsonism (RDP) or mutations of the RDP gene, document prevalence of the disease, and map its natural history.
- Trial name
- NCT00682513
- Where
- 2 sites in United States
- Volunteers
- 198 people
- Sponsor
- State University of New York at Buffalo
Vision Disorders
Effect of Lens Presentation on the Clinical Oculomotor Assessment at Near
This study will compare near clinical oculomotor parameters (heterophoria, vergence ranges, AC/A and accommodative findings) measured when lenses and/or prisms are introduced using three different instruments namely: (i) a…
- Trial name
- NCT02679313
- Testing
- Phoropter
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Frailty, Length of Stay
Evaluation of Prioritized Assessment for Older Patients Living With Frailty Presenting to the Emergency Department
The older population is getting older and growing in size worldwide. This requires healthcare to adapt to meet the complex medical and nursing needs of the older patient group.
- Conditions
- Frailty, Length of Stay, Emergency Department Visit, Older Patients
- Trial name
- NCT06869148
- Testing
- Prioritized assessment for older patients living with frailty
- Where
- Sweden
- Volunteers
- 1,217 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Coronary Artery Disease, Myocardial Infarction
Mi-RNAs and Specificity of Hs-TnT in Symptomatic ED Patients
Biomarkers play a key role in the diagnostic workup of patients presenting to an emergency department (ED). European and American guidelines recommend cardiac Troponin (T or I) as the biomarker gold standard for the diagnosis of…
- Trial name
- NCT02116153
- Sponsor
- University Hospital Heidelberg
Stroke, Foramen Ovale, Patent
Prospective Clinical Follow-up After the Percutaneous Closure of a Patent Foramen Ovale
Following a cryptogenic stroke, many patients are nowadays treated with the percutaneous closure of a patent foramen ovale (PFO), assuming that the aetiology of the stroke is secondary to a paradoxical embolism.
- Trial name
- PFO-HUG (NCT01149447)
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Geneva
Suspected CSF Shunt Obstruction
ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes Study
Primary objective is to demonstrate that data collected from ShuntCheck-Micro-Pumper (SCMP) testing results can be used in conjunction with imaging to diagnose shunt patency or obstruction in pediatric/adolescent subjects…
- Trial name
- NCT01881711
- Testing
- ShuntCheck-Micro-Pumper (SCMP), Imaging
- Where
- 11 sites in United States
- Volunteers
- 400 people
- Sponsor
- NeuroDx Development
Heart Failure
Clinical Utility of Subcutaneous Furosemide in Patients Presenting With Early Signs of Fluid Overload
This study will evaluate the usefulness of the subcutaneous administration of a new Lasix formulation. 20 patients will be evaluated in the first phase (pilot phase) and depending on the results, an additional 40 patients will be…
- Trial name
- NCT03359161
- Testing
- sc2Wear Furosemide Infusor
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Sepsis, Systemic Inflammatory Response Syndrome
Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?
The aim of this project is to test the utility of The Gene Z device (as of 2018 Gene Z no longer being used), now using In-Dx and other rapid identification techniques that the investigators have developed in the lab on…
- Conditions
- Sepsis, Systemic Inflammatory Response Syndrome, Infection Mixed, Infection, Bacterial
- Trial name
- NCT01904188
- Testing
- Gene Z or other rapid diagnostic techniques developed in our lab (as of 2018 not using Gene Z - now using In-Dx along with other developed techniquesregularly)
- Where
- 2 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Michigan State University
Revascularization of Immature Young Permenant Teeth
The Present Study Was Conducted to Evaluate Bioceramic Root Repair Material Versus Bio MTA in Revascularization of Immature Young Permenant Teeth.
The present clinical study wasdirected to evaluate bioceramic root repair material versus Bio MTA in Revascularization of Immature Young Permenant Teeth through: 1.
- Trial name
- NCT06630156
- Testing
- Revascularization of Immature Young Permenant Teeth
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Healthy
Phase 1 Clinical Study to Describe Biological Safety and Pharmacokinetics of Tyrphostin
Evaluate the biological safety and pharmacokinetics of tyrphostin AG-17 present in the solid oral formulations of the fixed-dose combination, in three different concentrations of the compound tyrphostin AG-17 contained 10 mg, 3.3…
- Trial name
- NCT05487781
- Testing
- Tirfostina/L-Carnitina
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Molecule X LLC