Clinical trials: Clinical Score
Gastric Cancer Peritoneal Metastases
A Prospective, Phase II Clinical Study of HIPEC Combined With NIPS and Tislelizumab Conversion Therapy for Gastric Cancer With Peritoneal Metastasis With Positive Cytology Alone or PCI Score ≤10
This study aims to evaluate the efficacy and safety of HIPEC combined with NIPS and tislelizumab conversion therapy for gastric/gastroesophageal junction cancer with positive cytology alone (CY1P0) or a Peritoneal Carcinomatosis…
- Trial name
- NCT07304258
- Testing
- HIPEC, NIPS, Paclitaxel Injection, S-1, tislelizumab
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Hebei Medical University
Enlargement of Tonsil or Adenoid
Bioclinical Profile of Adenotonsillar Hypertrophy in the Pediatric Population
Adenotonsillar hypertrophy is the principal cause of obstructive sleep apnea of childhood, yet little is known with regard to its pathophysiologic and molecular mechanisms.
- Trial name
- NCT03541434
- Testing
- Complete Blood Count, Tympanometry, Tonsillectomy and/or adenoidectomy
- Where
- 2 sites in Greece
- Volunteers
- 134 people
- Sponsor
- University of Patras
Appendicitis
Structured Management of Patients With Suspicion of Appendicitis Using a Clinical Score and Selective Imaging
Patients with acute abdominal pain and suspicion of appendicitis are common. The management of these patients is controversial with large variations between hospitals.
- Trial name
- STRAPPSCORE (NCT00971438)
- Testing
- Diagnostic imaging
- Where
- Sweden
- Volunteers
- 1,312 people
- Sponsor
- Ryhov County Hospital
Coronary Artery Disease, Angina Pectoris
Investigation of a Novel Gene Expression Test (ASGES or Corus CAD) for Diagnosis of Obstructive Coronary Artery Disease
The objective of this study is to collect data on the commercial use of Corus CAD (Age/Sex/Gene Expression score - ASGES) blood test to evaluate the clinical referral patterns of Primary Care Physicians after receipt of their…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- REGISTRY-I (NCT01557855)
- Testing
- Corus CAD (ASGES)
- Where
- 7 sites in United States
- Volunteers
- 342 people
- Sponsor
- CardioDx
Adenomyosis
Factors Associated With Adenomyosis and a Clinical Scoring System for the Diagnosis
Adenomyosis is a relatively common benign disorder in which endometrial gland and stroma are located within the myometrium resulting angiogenesis of the spiral vessel, hypertrophy of the surrounding smooth muscles and enlargement…
- Trial name
- NCT04830085
- Testing
- Hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Mersin University
Locally Advanced or Metastatic Non-small Cell Lung Cancer With Previously Untreated EGFR-sensitive Mutations and ECOG Performance Status Score ≥2
A Clinical Study Comparing the Efficacy and Safety of Befotertinib Versus Icotinib in Patients With Previously Untreated EGFR-sensitive Mutation-positive Non-small Cell Lung Cancer With ECOG Score ≥2
This study is a multicenter, randomized, open-label, parallel-controlled clinical trial. It is designed to evaluate the efficacy and safety of Befotertinib versus Icotinib as first-line treatment in patients with previously…
- Trial name
- BEST2 (NCT07900243)
- Testing
- Befotertinib, Icotinib
- Volunteers
- 100 people
- Sponsor
- Zhou Chengzhi
Urothelial Carcinoma
B7-Family Score in Urothelial Carcinoma
Immunotherapy has been found to confer substantial survival benefits to the patients with higher mutation burdens, which become the first biomarker approved by FDA in urothelial carcinoma (UC).
- Trial name
- NCT06169904
- Testing
- Cisplatin injection
- Volunteers
- 215 people
- Sponsor
- Shanghai Zhongshan Hospital
Airway Management, Intubation, Intratracheal
The Difficult Airway Management Trial: "The DIFFICAIR-Trial"
In general anesthetic the patient is deprived of his awareness and ability to breathe. It is therefore one of the most important tasks in anesthesia to ensure the patient's airway and breathing.
- Trial name
- DIFFICAIR (NCT01718561)
- Testing
- SARI
- Where
- 28 sites in Denmark
- Volunteers
- 76,058 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Atrial Fibrillation New Onset
PARADISE: Predicting AF After Cardiac Surgery
The PARADISE study aims to develop and validate prediction tools to identify patients at risk of Atrial Fibrillation (AF) after cardiac surgery.
- Trial name
- PARADISE (NCT05255224)
- Testing
- Not applicable as observational study
- Where
- United Kingdom
- Volunteers
- 13,684 people
- Sponsor
- University of Oxford
Stroke, Hemiplegia
Relationship Between Clinical Status and Nerve Conduction Test Findings in Patients With Unilateral Hemiplegia
Stroke-related hemiplegia may be accompanied by peripheral nerve conduction abnormalities, which may contribute to motor impairment and functional limitations.
- Conditions
- Stroke, Hemiplegia, Intracranial Hemorrhage, Spontaneous
- Trial name
- NCT07685691
- Testing
- Nerve Conduction Study
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Baskent University
Rheumatoid Arthritis
The Effect of Corticotrophin (ACTH) in Combination With Methotrexate in Newly Diagnosed Rheumatoid Arthritis Patients
The purpose of the study is to evaluate the effect of the utilization of two doses of corticotrophin ( ACTH) as a treatment in patients with early onset rheumatoid arthritis as an alternative to conventional steroid therapy by…
- Trial name
- NCT01948388
- Testing
- corticotrophin 80 units
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Gaylis, Norman B., M.D.
Acute Bronchitis
A Study to Evaluate the Efficacy and Safety of DW5121 Compared to DW51211 and DW51212
This is a Phase 3, randomized, double-blind, active-controlled, parallel-group, multi-center clinical trial to evaluate the efficacy and safety of DW5121 compared to DW51211 and DW51212 in patients with acute bronchitis.
- Trial name
- NCT07093697
- Testing
- DW5121, DW51211, DW51212
- Where
- 8 sites in South Korea
- Volunteers
- 273 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Mild and Moderate Atopic Dermatitis Patients, Atopic Dermatitis (AD)
Clinical Trial of an Ointment in Patients With Mild and Moderate Atopic Dermatitis
Atopic dermatitis (AD) is a chronic skin disorder, which negatively impacts up to 20% children and 3% adults in the world. The main AD treatments aim to regress clinical manifestations, improve and restore skin lesions.
- Trial name
- NCT07653386
- Testing
- S.formosum-containing ointment, commercial moisturizer
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- VinUniversity
Ulcerative Colitis
A Study Evaluating The Efficacy And Safety Of CP-690,550 In Patients With Moderate To Severe Ulcerative Colitis
This study is designed to evaluate the efficacy and safety of tofacitinib (CP-690,550) in patients with moderate to severe ulcerative colitis who have failed or be intolerant to one of following treatments for ulcerative colitis…
- Trial name
- OCTAVE (NCT01465763)
- Testing
- tofacitinib
- Where
- 178 sites in United States, Australia and 26 more
- Volunteers
- 614 people
- Sponsor
- Pfizer
Pain
Effect of Lidocaine Spray for Pain Relief During Endometrial Biopsy: a Randomized, Double-blind, Placebo-controlled Clinical Trial
The effect of lidocaine spray on pain relief during endometrial sampling.
- Trial name
- NCT02039661
- Testing
- Lidocaine Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kayseri Education and Research Hospital
Polyp of Colon
Pronostic Score of Morbidity to Determine Risk of Complications After Endoscopic Submucosal Dissection for Colorectal Lesions
The mains complications in colo-rectal dissection are the pain, the delayed bleeding and the perforation and represent around 10%.
- Trial name
- NCT04647266
- Testing
- endoscopic submucosal dissection
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Central Hospital, Nancy, France
Croup
Efficacy of Nebulized Beclomethasone Dipropionate (BDP) in the Treatment of Moderate Croup
Acute laryngotracheobronchitis, better known as croup, is one of the common respiratory complaints among children and the most common cause of airway obstruction in children aged six months to six years.
- Trial name
- NCT00938353
- Testing
- beclomethasone dipropionate suspension for nebulisation 800 mcg/2 ml
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Type 2 Diabetes Mellitus (T2DM), Insulin Resistance
Validation of the Snouda Metabolic Score for Phenotyping and Guiding Reversal in Type 2 Diabetes
This study tests a new tool called the Snouda Metabolic Score (SMS) that helps doctors identify the specific metabolic problems driving Type 2 Diabetes in each individual patient.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Insulin Resistance, Metabolic Syndrome
- Trial name
- SMS-VAL (NCT07606872)
- Testing
- Phenotype-Matched Dietary Protocol, Structured Progressive Exercise Protocol, Targeted Nutritional Supplementation
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Salah Snouda
Sepsis, Critical Illness
SOFA Score with Serum Procalcitonin Versus SOFA Score with Neutrophil/lymphocyte Ratio in Predicting Sepsis and Clinical Outcomes in I.C.U.
Sepsis remains a critical life-threatening and a healthcare challenge worldwide. Sepsis is implicated in a mortality rate that ranges between 25 - 30% in severe cases and 40-70% in septic shock, also, Post sepsis, lower quality…
- Trial name
- SOFA-PROVSNL (NCT06847477)
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Graves' Ophthalmopathy
The Effect of Early Total Thyroidectomy in the Course of Graves' Orbitopathy
The relationship between the method of the treatment of hyperthyroidism due to Graves' disease and the course of Graves' ophthalmopathy is debated.
- Trial name
- NCT01056419
- Testing
- Total Thyroidectomy, Propylthiouracil
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara University