Clinical trials: Clinical Study
Healthy
A Safety, Tolerability and Pharmacokinetics Study of JNJ-54861911 in Healthy Japanese Male Participants
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK, study of the way a drug enters and leaves the blood and tissues over time) of single-ascending oral doses of JNJ-54861911 in healthy…
- Trial name
- NCT02180269
- Testing
- JNJ-54861911 (25 mg), JNJ-54861911 (50 mg), JNJ-54861911 (100 mg)
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutical K.K.
Healthy Human Volunteers
Single and Multiple Ascending Dose Safety Study of XPF-001 in Healthy Volunteers
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of single and multiple doses of XPF-001 in healthy volunteers. The effect of food on the pharmacokinetics of XPF-001 will also be studied.
- Trial name
- NCT00813670
- Testing
- XPF-001
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Xenon Pharmaceuticals Inc.
Cervical Cancer
Immunogenicity and Safety Study of NBP615 in Healthy Female
This was a randomized, double-blind, active-controlled, phase I/II clinical trial to enroll 200 healthy female including 80 healthy adult aged 19 to 26 years and 120 adolescents aged 9 to 13 years.
- Trial name
- NCT04453241
- Testing
- NBP615, Gardasil
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- SK Bioscience Co., Ltd.
Healthy, Safety and Tolerability
Evaluating the Safety, Tolerability, and Pharmacokinetics of DF-003 in Healthy Subjects
The goal of this clinical trial is to evaluate the safety, tolerability, and pharmacokinetics (PK; drug metabolism) of DF-003 after oral administration of single and multiple ascending doses in healthy subjects.
- Trial name
- NCT05997641
- Testing
- DF-003
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Shanghai Yao Yuan Biotechnology Ltd. (also known as Drug Farm)
Cancer, mCRC
Phase I PK Comparison of HLX05 vs. Erbitux® in Healthy Chinese Males: Safety, Immunogenicity, and Pharmacokinetics
This is a randomized, single intravenous dose, parallel study to compare the PK characteristics, safety, tolerability, and immunogenicity of HLX05 vs. Erbitux® (US-, EU-, and CN-sourced) in healthy adult male Chinese subjects.
- Trial name
- NCT06980454
- Testing
- HLX05, EU-Erbitux®, US-Erbitux®
- Where
- 2 sites in China
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Shanghai Henlius Biotech
Aging
Changing in Skin Physiology After Microdroplet Placement of Stabilized Hyaluronic Acid in Aging Faces
IMPORTANCE Skin rejuvenation can be achieved effectively and safely by injection of a stabilized hyaluronic acid (HA)-based gel of nonanimal origin (NASHA) injection using a stamp-type electronic multineedle injector.
- Trial name
- NCT02312154
- Testing
- Restylane Vital
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Konkuk University Hospital
Healthy Volunteers
Bioequivalence of Abiraterone Acetate Tablets in Healthy Chinese Volunteers
An open, randomized, single-dose, three-cycle, three-sequence crossover study was conducted in 36 healthy volunteers under fasting condition to evaluate the bioequivalence of two abiratone acetate tablets.
- Trial name
- NCT04863105
- Testing
- Abiraterone acetate tablets(Zecke ®250 mg);Abiraterone acetate tablets(250 mg)
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Pregnancy Related
The OPTIMIZE Study: Optimizing Patient Navigation for Perinatal Care
This study will develop and test an intervention, called OPTIMIZE, which includes the use of a perinatal checklist by clinic staff and provision of patient navigation support to African American pregnant women.
- Trial name
- NCT04261894
- Testing
- OPTIMIZE
- Where
- United States
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atopic Dermatitis, Atopic Dermatitis Eczema
Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1%
The investigational lotion is envisaged as an short- and long term "Ease \& Prevent" monotherapy for adults and children with mild to moderate eczema.
- Conditions
- Atopic Dermatitis, Atopic Dermatitis Eczema, Atopic Rash, Rash
- Trial name
- ATOFEX-1 (NCT05461456)
- Testing
- Fexofenadine Hydrochloride Topical Lotion 1% (OP2101)
- Where
- Bangladesh
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- OrchestratePharma GmbH
Parkinson Disease
A Phase I Study of TRN501 in Healthy Volunteers
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of TRN501 following a single administration of TRN501 or placebo to healthy adult male volunteers.
- Trial name
- NCT06453551
- Testing
- TRN501 - Dose 1, TRN501 - Dose 2, TRN501 - Dose 3
- Where
- Japan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- SNLD, Ltd.
Healthy Participants
Perceived Barriers and Facilitators to Physical Activity in Turkish Youth
Physical activity is a key determinant of physical and mental health among youth; however, participation levels are often influenced by various perceived barriers and facilitators.
- Trial name
- NCT07320131
- Where
- Turkey (Türkiye)
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Istinye University
Postpartum Depression
An Evaluation and Factor Analysis for Maternal Mental Health
An Evaluation and Factor Analysis for Maternal Mental Health - The Analytic Study of the Shin Kong Wu Ho-Su Memorial Hospital Objectives： 1. To construct a screening tool for domestic maternal mental health 2.
- Trial name
- NCT01423331
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Dyslipidemia
A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.
The purpose of the study is to assess the effect of AZD0780 on the pharmacokinetics of rosuvastatin, and to assess the safety and tolerability of AZD0780 single dose, in healthy participants administered alone and in combination…
- Trial name
- NCT05787002
- Testing
- AZD0780, Rosuvastatin
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma, COPD
An Evaluation of 9MW1911 Injection in Healthy Subjects
This study is a randomized, double-blind, dose-escalating phase I clinical study to evaluate the safety, tolerability and pharmacokinetics of 9MW1911 injection in healthy subjects.
- Conditions
- Asthma, COPD, Atopic Dermatitis
- Trial name
- NCT05803902
- Testing
- Experimental drug 9MW1911
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mabwell (Shanghai) Bioscience Co., Ltd.
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Bupropion
Drug Interaction Study of Multiple Doses of Isavuconazole and a Single Dose of Bupropion
The purpose of this study is to assess the effect of multiple doses of isavuconazole on the pharmacokinetics of a single dose of bupropion.
- Conditions
- Pharmacokinetics of Isavuconazole, Pharmacokinetics of Bupropion, Healthy Volunteers
- Trial name
- NCT01635972
- Testing
- Isavuconazole, bupropion hydrochloride
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Ehlers-Danlos Syndrome
Registry of Ehlers-Danlos Syndrome
RED is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- RED (NCT04133272)
- Where
- Italy
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Acute Mountain Sickness
Alternative Treatments in Acute Mountain Sickness
The purpose of this research is to support a hypothesis that osteopathic manual medicine (OMM) and / or a 10 cmH2O end-expiratory pressure (PEEP) could be used in the prevention of acute mountain sickness (AMS).
- Trial name
- TAIA (NCT03956472)
- Testing
- Osteopathic protocol for improving drainage of LCS, PEEP 10cmH2O, Fake Osteopathic protocol
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut de Formation et de Recherche en Médecine de Montagne
Gastrointestinal Diseases, Cow's Milk Intolerance
Goat Milk Infant Formula Comfort Study
In this study, the investigators aim to assess that infants with mild symptoms have significantly less (severe) symptoms after 14 days goat milk-based formula use compared to infants using cow's milk-based formula supplemented…
- Trial name
- NCT06301139
- Testing
- Goat milk-based infant formula, Cow's milk-based infant formula with probiotic drops
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Cognitive Functioning
Efficacy Study of AlphaBRAIN Administered Orally
The manufacturers of AlphaBRAIN(TM) claim that their product, when taken as directed, has beneficial effects on cognition. The active ingredient in AlphaBRAIN, Huperzine A, is a naturally occurring compound found in firmoss and…
- Trial name
- NCT02739139
- Testing
- AlphaBrain
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Onnits Labs, LLC
Neurofibromatosis 2, Meningioma
AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas
The goal of this clinical research study is to learn if the study drug AZD2014 can shrink growing or symptomatic meningiomas.
- Trial name
- NCT02831257
- Testing
- AZD2014
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.