Clinical trials: Clinical Study
Cognitive Function, Cardiopulmonary Function
Commuter Air Pollution Intervention Study
Traffic related air pollution is a well-recognised and much studied contributor to smog and is linked to a number of adverse health outcomes.
- Conditions
- Cognitive Function, Cardiopulmonary Function, Saliva Stress Hormones, Air Pollution Exposure
- Trial name
- CAPI (NCT02277002)
- Testing
- Cabin Air Filtration
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Health Canada
Alopecia Areata
Alefacept in Patients With Severe Scalp Alopecia Areata
The purpose of this study is to examine prospectively the safety and efficacy of alefacept in the treatment of subjects with severe alopecia areata of the scalp.
- Trial name
- NCT00167102
- Testing
- Alefacept
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Type 1 Diabetes, T1D
DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions
This prospective single-arm feasibility study evaluates the Adhera Caring Digital Program for Obesity (ACDP-O), a family-centered digital health intervention designed to support adolescents and young adults with…
- Conditions
- Type 1 Diabetes, T1D, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus
- Trial name
- DASH-Obesity (NCT07638345)
- Testing
- Adhera Caring Digital Program-Obesity (ACDP-O)
- Where
- Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Adhera Health, Inc.
Candidates for BRCA 1/2 Genetic Testing
A Study of the Communication of Genetic Test Results By Telephone: A Multi-Center Study
The overall goal of the proposed research is to evaluate psychosocial and behavioral outcomes (i.e.risks and benefits) of an innovative and efficient delivery model for genetic testing, telephone communication, as an alternative…
- Trial name
- NCT01736345
- Testing
- Genetic Providers, Visual Aids, Post-Disclosure Asessments
- Where
- 5 sites in United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Rabies
Immunogenicity and Safety Study of A New Chromatographically Purified Vero Cell Rabies Vaccine With ID Regimen and ERIG
A comparative,randomized (1:1)study to evaluate the safety and immunogenicity of a new chromatographically purified vero cell rabies vaccine (SPEEDA) and chromatographically purified vero cell rabies vaccine (SPEEDA)which is…
- Trial name
- NCT01137045
- Testing
- SPEEDA and TRCS SPEEDA
- Where
- 2 sites in Thailand
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Queen Saovabha Memorial Institute
Rheumatoid Arthritis, Osteoarthritis
Relative Bioavailability Study of Naproxen Delayed-Release Tablets (375 mg)
The purpose of this study is to demonstrate the relative bioavailability of Naproxen delayed-release tablets (375 mg).
- Trial name
- NCT00959439
- Testing
- Naproxen Delayed Release Tables, 375 (Gevena Pharmaceuticals, Inc.), Naproxen (EC-Narosyn) Delayed Release Tables, 375 (Syntex (USA), Inc.)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sandoz
Oral Health
Analysis of Oral Health of Students and Former Students of Undergraduate and Postgraduate Programs at the University of São Paulo.
This study aims to evaluate oral and systemic health conditions among students and former students of undergraduate and postgraduate programs at the University of São Paulo over five years.
- Trial name
- NCT06853639
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Prostate Cancer, PET/CT
Head-to-head Comparison of [68Ga]Ga-PSMA-D5 With [68Ga]Ga-PSMA-11 PET/CT in PCa Diagnosis, Recurrence, and Metastasis
To prospectively evaluate the radiodrug biodistribution of a novel PET imaging agent [68Ga]Ga-PSMA-D5 in different organs of prostate cancer patients and its diagnostic efficacy in the diagnosis, recurrence and metastasis of…
- Trial name
- NCT05955677
- Testing
- [68Ga]Ga-PSMA-D5, [68Ga]Ga-PSMA-11
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Active Mild Ulcerative Colitis, Active Moderate Ulcerative Colitis, Healthy Subjects
TD-3504 SAD in Healthy Subjects and Subjects With Ulcerative Colitis (UC)
This study is designed to evaluate the safety, tolerability, and pharmacokinetics (PK) of single-dose TD-3504 and single dose 15N2-tofacitinib in healthy subjects and subjects with UC.
- Trial name
- NCT03103412
- Testing
- TD-3504, 15N2-tofacitinib
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Healthy, Enteric Hyperoxaluria
Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2).
- Trial name
- NCT05650112
- Testing
- FB-001
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federation Bio Inc.
Temporomandibular Arthritis
Intra-articular Injection for the Relief of Temporomandibular Joint Pain
Which is more effective in the treatment of nonspecific temporomandibular osteoarthritis: platelet-rich plasma (PRP), hyaluronic acid, or triamcinolone acetonide?
- Trial name
- NCT07571265
- Testing
- platelet rich plasma and triamcinolone acetonide and hyaluronic acid and saline intra articular injection
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Clubfoot
Rate Of Residual Clubfoot Deformity With Correlation To Absence Of Peroneus Tertius Muscle
Rate Of Residual Clubfoot Deformity With Correlation To Absence Of Peroneus Tertius Muscle , A Prospective Study.
- Trial name
- NCT03749265
- Testing
- Ultrasound test
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Urinary Incontinence, Quality of Life
Effect of HIFEM® Treatment of Urinary Incontinence in Women in Primary Care. A Randomized Controlled Trial
Urinary incontinence (UI) is a condition with involuntary leakage of urine. UI has a significant impact on health related quality of life, poorer sleep quality and sexual function, reduced participation in social and physical…
- Conditions
- Urinary Incontinence, Quality of Life, Menopause, Mental Health Issue
- Trial name
- NCT06485167
- Testing
- HIFEM- chair
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Infections, Papillomavirus
A Single Centre Study to Evaluate the Safety and Immunogenicity of the Human Papillomavirus Vaccine (GSK-580299) in Chinese Females
A phase I, open label, single-centre study to evaluate the safety and immunogenicity of GlaxoSmithKline Biologicals' HPV -16/18 L1 VLP AS04 vaccine (GSK 580299, Cervarix TM), administered intramuscularly according to a 0, 1…
- Trial name
- NCT00549900
- Testing
- GSK580299 (Cervarix™ , HPV -16/18 L1 VLP AS04 vaccine)
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Malaria
Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen
This study is being done to assess the possibility of the potential integration of malaria vaccine into the EPI regimen. It will evaluate whether the malaria vaccine is safe and immunogenic in infants aged 6 to 10 weeks at first…
- Trial name
- NCT00436007
- Testing
- GSK 257049, Tritanrix™ HepB/Hib, Rouvax™
- Where
- 3 sites in Gabon, Ghana and 1 more
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Depression, Psychological Distress
A Pilot Study of the Effect of Personalized Depression Risk Communication
Depression is a highly prevalent and disabling mental health problem. It is associated with significant morbidity and mortality and it has a significant economic impact.
- Trial name
- NCT04519892
- Testing
- PDRC, Coach guidance
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Erosion of Teeth, Unspecified
Prophylactic Effect of a CANDIDA Mouthwash, Containing the Curolox™ Peptide
In vitro results showed a protective effect against acids for the mouthwash containing Curolox™ peptide. The goal of this in situ study is to detect the Curolox™ peptide under natural oral conditions on the tooth surface and to…
- Trial name
- NCT02308436
- Testing
- Candida Mouthwash with Curolox™ Peptide
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mibelle AG
Breast Cancer, Cervical Cancer
Behavioral Intervention Study for Better Breast and Cervical Cancer Control for Korean American Women
The long-term goal of this study is to build a sustainable,community-based outreach program using Korean American community health workers (CHWs) to promote breast and cervical screening among Korean American women, thereby…
- Trial name
- NCT00857636
- Testing
- Health literacy, health message
- Where
- United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy
Effect of Bergamot Juice on LDL Cholesterol Level in Healthy Subjects
A single-centre, randomized (1:1), open label, controlled study to assess the lipid-lowering effect at 12 weeks of 400 cc/die bergamot juice consumption compared to free diet in healthy subjects
- Trial name
- NCT05589636
- Testing
- Bergamot Juice
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Healthy Volunteers
A Study to Investigate the Absorption, Metabolism and Excretion of [14C]-BGB-11417
The main objective of this study is to determine the mass balance, routes of elimination, and pharmacokinetics of [14C]-BGB-11417 in healthy male participants along with determining the concentrations of radioactivity in plasma…
- Trial name
- NCT05844111
- Testing
- [14C]-BGB-11417
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- BeiGene
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