Clinical trials: Clinical Study
Non Small Cell Lung Cancer, Healthy
Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments, Using Multiomics
The goal of this exploratory study is understand the mechanisms of response to immunotherapy in Non-Small Cell Lung Cancer patients.
- Trial name
- PROPHETIC (NCT05736029)
- Testing
- blood, stool and tissue samples collection
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- OncoHost Ltd.
Healthy Volunteers
A Study to Assess the Safety and Tolerability of E2511 in Healthy Adult and Elderly Participants
The primary objective of this study is to evaluate the safety, tolerability, and plasma pharmacokinetic (PK) of E2511 following multiple oral doses in healthy adult participants.
- Trial name
- NCT05147337
- Testing
- E2511
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Aging, Pain
RHA® 4 With New Anesthetic - Nasolabial Folds
This is a randomized, controlled, double-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA® 4 with New Anesthetic Agent is non-inferior to RHA® 4 (with lidocaine) in terms of…
- Trial name
- NCT04087395
- Testing
- RHA®4 with new anesthetic agent, RHA®4-Lidocaine
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Vitamin D Deficiency
A Pilot Study of the Effect of Dietary Fat Type and Amount on Vitamin D3 Absorption
This study will examine whether the amount and type of fat, mono-unsaturated fat (MUFA) vs. poly-unsaturated fat (PUFA), in a meal affects the absorption of vitamin D, which is taken after that meal.
- Trial name
- MUFA/PUFA (NCT01508845)
- Testing
- cholecalciferol
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Tufts University
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Physical Activity, Metabolic Diseases
Effect of a Multicomponent Intervention in Children and Adolescents
The aim of this study was: to evaluate the effectiveness of a multicomponent pilot intervention in improving physical fitness (PF) and metabolic risk markers in children and adolescents; and examine if possible changes in PF are…
- Trial name
- NCT02929472
- Testing
- Physical exercise, without physical exercise
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Clarice Maria de Lucena Martins
Observational Study
Project VERANDA: Requirement Analysis Survey
Between 0.6% and 22.2% of the global adult male population has a sexual interest in children (SIIC), depending on evaluation methods [1].
- Trial name
- NCT07424872
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Berlin Institute of Health @ Charité
Healthy
A Relative Bioavailability Study of Quinine Sulfate Capsules Under Fasting and Fed Conditions
The purpose of this study is to evaluate and compare the relative bioavailability of Quinine Sulfate 324 mg capsules, manufactured by the Mutual Pharmaceutical Company, to Quinine Sulphate 300 mg tablets, manufactured by the…
- Trial name
- NCT00727272
- Testing
- Quinine Sulfate Capsules 324 mg, Quinine Sulphate Tablets 300 mg
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mutual Pharmaceutical Company, Inc.
Healthy
Food Study of Meloxicam Tablets 15 mg and Mobic® Tablets 15 mg
The objective of this study was to investigate the bioequivalence of Mylan's meloxicam 15 mg tablets and Boehringer Ingelheim's Mobic® 15 mg tablets following a single, oral 15 mg (1 x 15 mg) dose administration under fed…
- Trial name
- NCT00649675
- Testing
- Meloxicam Tablets 15 mg, Mobic® Tablets 15 mg
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Postpartum Contraception, Depot Medroxyprogesterone Acetate
Measuring Lactation Initiation After Early Postpartum Injectable Progestin (DMPA) Use Among Women in Dhanusha District of Nepal: A Pilot Study
This is a pilot study of early postpartum initiation of the injectable progestin contraception, depo medroxyprogesterone acetate (DMPA), among 40 postpartum people.
- Conditions
- Postpartum Contraception, Depot Medroxyprogesterone Acetate, Lactation, DMPA
- Trial name
- NCT06816901
- Testing
- Depo Medroxyprogesterone acetate
- Where
- Nepal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Wrinkles
Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds
The purpose of this study is to see how well Juvederm Ultra XC or Juvederm Ultra Plus XC, and BOTOX Cosmetic, work compared to each other and when used together for the cosmetic treatment of age-associated wrinkles and folds of…
- Trial name
- JUVE_BTX (NCT01269801)
- Testing
- onabotulinumtoxinA, JUVÉDERM
- Where
- 3 sites in United States, Canada
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- AboutSkin Dermatology and DermSurgery, PC
Healthy
A Drug-Drug Interaction Study of Carbamazepine and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-012)
Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer. The purpose of this study is to learn what happens to opevesostat in a person's body over time (a pharmacokinetic or PK study).
- Trial name
- NCT06633419
- Testing
- Opevesostat, Prednisone, Fludrocortisone acetate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cancer
A Study of Vismodegib in Patients With Advanced Solid Malignancies Including Hepatocellular Carcinoma With Varying Degrees of Renal or Hepatic Function
This is a Phase Ib, open-label, multiple-center, multiple-dose study designed to evaluate the pharmacokinetics and safety of vismodegib in patients with advanced solid malignancies (including hepatocellular carcinoma and…
- Trial name
- NCT01546519
- Testing
- Vismodegib
- Where
- 5 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Healthy Participants
A Single and Multiple Ascending Dose Study of BMS-986318 in Healthy Participants
A study to evaluate single and multiple ascending doses of experimental medicine BMS-986318 in healthy participants.
- Trial name
- NCT04082741
- Testing
- BMS-986318
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy Volunteers
A Controlled-Feeding Study to Assess the Effect of Cashews on Fasting Lipoprotein Levels
This study will assess the nutritional effect of cashews on LDL-C concentrations and secondarily on other aspects of the fasting lipoprotein lipid profile in healthy men and women with moderately elevated cholesterol.
- Trial name
- NCT02769741
- Testing
- Cashews followed by Control, Control followed by Cashews
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Kraft Heinz Company
Respiratory Syncytial Virus Infections
A Study to Assess Safety, Tolerability and Immunogenicity of the Live Attenuated hRSV Vaccine rBCG-N-hRSV
Human respiratory syncytial virus (hRSV) is the main cause of lower respiratory tract infection in children under one year of age.
- Trial name
- EVA-VRS01 (NCT03213405)
- Testing
- rBCG-N-hRSV 1/100, rBCG-N-hRSV 1/10, rBCG-N-hRSV full dose
- Where
- Chile
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Breastfeeding
Alive & Thrive Nigeria Breastfeeding Promotion in Urban Private Facilities Study
The purpose of this study was to evaluate the effect of a breastfeeding promotion intervention on breastfeeding intentions, early initiation of breastfeeding, and exclusive breastfeeding among clients in private health facilities…
- Trial name
- NCT04835051
- Testing
- Breastfeeding promotion
- Where
- 20 sites in Nigeria
- Volunteers
- 1,220 people, healthy volunteers welcome
- Sponsor
- RTI International
Human Papillomavirus
A Study to Compare the Impact of a School Based HPV Program on Vaccination Uptake and Completion Rates
The purpose of this study is to evaluate the impact of a school-based Human Papillomavirus (HPV) vaccination program to determine if the combination of increased disease and vaccine education coupled with the removal of barriers…
- Trial name
- NCT01526551
- Testing
- HPV Vaccine and HPV-related Health Education, Reduction of barriers
- Where
- 2 sites in United States
- Volunteers
- 935 people, healthy volunteers welcome
- Sponsor
- Lake Cumberland District Health Department
Lumbar Disc Herniation, Gait Analysis
Effect of Chuna Manipulation Therapy on Gait in Patients With Lumbar Disc Herniation
Prospective Observation Study of the Effect of Chuna Manipulation Therapy on Gait in Patients With Lumbar Disc Herniation
- Conditions
- Lumbar Disc Herniation, Gait Analysis, Manual Therapy
- Trial name
- NCT03858556
- Testing
- Chuna manipulation, Herbal medicine, Bee venom pharmacopuncture
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jaseng Medical Foundation
Dermatitis, Atopic
Phase IIa Study of WBI-1001 Cream for Atopic Dermatitis
WBI-1001 is a synthetic,new, non-steroid, small molecule being developed as a candidate drug for the topical, cream treatment of inflammatory skin diseases.
- Trial name
- WBI-1001-201 (NCT00837551)
- Testing
- WBI-1001
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Welichem Biotech Inc.
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