Clinical trials: Clinical Study
Hypertension
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fasting Conditions in Healthy Volunteers
The purpose of this clinical trial is to evaluate the pharmacokinetics and the safety after administration of "BR1015" and co-administration of "BR1015-1" and "BR1015-2" under fasting conditions in healthy volunteers
- Trial name
- NCT06008028
- Testing
- BR1015, BR1015-1, BR1015-2
- Where
- South Korea
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Healthy Volunteers
A Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0941 and the Effect of Food and Proton Pump Inhibition on GDC-0941 Tablet Pharmacokinetics in Healthy Volunteers
This is a Phase I, randomized, two-part, single-center pharmacokinetics (PK) study to assess the relative bioavailability of capsule and tablet formulations of GDC-0941 in the fasted state (Part 1) and to determine the effect of…
- Trial name
- NCT00999128
- Testing
- GDC-0941, rabeprazole
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
The Study Focus on no Specific Condition
Interpretation of Health News Items Reporting Results of Phase I/II (Non-randomized) Trials With or Without Spin by French-speaking Population
The main objective of this study is to compare the interpretation of health news items reporting results of phase I/II (non-randomized) trials with or without spin (i.e., distortion of research results).
- Trial name
- NCT03094130
- Testing
- News items with spin, News items without spin
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity and Obesity-related Medical Conditions, Appetite
Effects of Meal Characteristics on Appetite
The overall aim of the study is to determine effects of different meal characteristics on energy intake, eating rate and appetite.
- Trial name
- NCT07178405
- Testing
- Meal low in energy density, low in ultra-processed food, Meal low in energy density, high in ultra-processed food, Meal high in energy density, low in ultra-processed food
- Where
- Sweden
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Healthy Participants, Non-cystic Fibrosis Bronchiectasis
A Phase 1a/1b Study to Investigate the Safety, Tolerability, Microbiological Response, and Pharmacokinetics of Inhaled Rev-56 in Adult Healthy Volunteers and Adult Non-cystic Fibrosis Bronchiectasis (NCFB) Patients With Chronic P. Aeruginosa
This is a Phase 1a/1b study to test the safety, tolerability, microbiological response, and pharmacokinetics of inhaled Rev-56 compared to placebo in adult healthy participants and non-cystic fibrosis bronchiectasis (NCFB)…
- Trial name
- NCT07709494
- Testing
- Rev-56 for Inhalation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Revagenix, Inc.
Respiratory Syncytial Virus Immunization
Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older
Brief Summary of Stage 1: The purpose of Stage 1 (Phase I/IIa) was to assess the safety and immunogenicity of a single intramuscular (IM) injection of 3 dose-levels of an Respiratory Syncytial Virus (RSV) vaccine candidate…
- Trial name
- NCT05639894
- Testing
- RSV vaccine candidate
- Where
- 33 sites in United States, Australia and 1 more
- Volunteers
- 865 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Drinking Behavior
Motivating Campus Change Project Pilot Study
This study tests the optimization and delivery feasibility of personalized feedback interventions to address harmful alcohol use among college students.
- Trial name
- MC2 Pilot (NCT03962751)
- Testing
- Simultaneous Post Feedback Intervention Delivery, Sequential Post Feedback Intervention Delivery, Text Message Boosters
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Washington
Intrauterine Insemination
A Study of Music Therapy to Support Intrauterine Insemination
The purpose of this research is to learn if playing music in the room during an intrauterine insemination procedure decreases anxiety and pain for patients at the time of the procedure.
- Trial name
- NCT05492331
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gynecological Surgery
Effect of Combined Administration of Sevoflurane and Remimazolam on Emergence
Enhanced recovery after surgery (ERAS) protocols are being explored to improve patient outcomes. The method of inducing anesthesia and maintenance using inhalation anesthetics is common but may delay recovery.
- Trial name
- NCT06385002
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Job Engagement, Leisure Activities
The Effect of Sports and Arts on Job Engagement Among Physicians
The goal of this observational study was to learn about the relationship between the sociodemographic characteristics or leisure time activities of physicians and their job engagement.
- Trial name
- NCT06634602
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Buğu Usanma Koban
Chronic Kidney Diseases, Magnetic Resonance Imaging
Material Balance Study of TQ-B3525
A clinical study to investigate the absorption, metabolism and excretion of [14C] TQ-B3525 in Chinese adult male healthy subjects, aiming to quantitatively analyze the total radioactivity in the excreta of male healthy subjects…
- Trial name
- NCT05675202
- Testing
- TQ-B3525
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Heart Transplant
A Multicenter Clinical Study of Ultrasound Multimodal Imaging in the Evaluation of Heart Transplantation
The aims of this study are to 1. Assess the preoperative and postoperative atrial and ventricular structure and function comprehensively in heart transplantation; 2.
- Trial name
- HT (NCT04974372)
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Xie Mingxing
Obsessive-Compulsive Disorder
Modulating Prefrontal Circuits Underlying Behavioral Flexibility in OCD: A TMS Study
This study investigates whether slow-frequency repetitive transcranial magnetic stimulation targeting frontal pole can acutely modulate brain circuits which show abnormal functioning during behavioral flexibility in…
- Trial name
- NCT04165577
- Testing
- rTMS
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Alzheimer Disease, Alzheimer Disease (AD)
Phase I Clinical Study of AV-1959R: Abeta-targeting Anti-Alzheimer's Vaccine
This Phase 1 clinical trial evaluates the safety, tolerability, and immune response of the adjuvanted AV-1959R vaccine in healthy adults aged 40-60.
- Conditions
- Alzheimer Disease, Alzheimer Disease (AD), Alzheimers Disease Prevention
- Trial name
- NCT06831812
- Testing
- AV-1959R (Abeta vaccine)
- Where
- Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Nuravax, Inc.
IUD, IUD Insertion Complication
IUD Placement Without Sounding
The purpose of this study is to determine the feasibility of a uterine sound sparing technique for levonorgestrel 52 mg intrauterine device (IUD) placement. This study will be conducted in three phases.
- Conditions
- IUD, IUD Insertion Complication, IUD; Complications
- Trial name
- NCT05700812
- Testing
- Sound sparing levonorgestrel 52 mg IUD placement
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Binge Eating Disorder, Obesity
Binge Eating Disorder and Obesity : Functional MRI Study
Obesity, defined as BMI> 30kg / m2, is a major public health problem, with devastating medical and psychological consequences. 30% of obese suffer from BED type of eating disorders.
- Trial name
- BED (NCT02868619)
- Testing
- Functional MRI, ADO-BEDS scale, R-CMAS scale
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Type2diabetes
Correlation of Xanthelasma With Atherosclerosis, Hepatic Fat and Fibrosis
Patients with diabetes with clinical feature of Xanthelasma will show increased Atherosclerosis. Objectives: Primary 1. To correlate xanthelasma and its severity to pulse wave velocity and atherosclerosis as see in carotid…
- Trial name
- NCT05945030
- Testing
- Clinical Examination
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Healthy
A Bioequivalence Study of Sanchi-Tongshu Capsule (Enteric Coated Pellets)
24 healthy male volunteers are to be assigned to take orally Sanchi-Tongshu Capsule (Enteric coated pellets) and Sanchi-Tongshu Capsule in fasting condition according to a randomized, crossover, self-control method, with…
- Trial name
- NCT02316730
- Testing
- Sanchi-Tongshu Capsule (Enteric coated pellets), Sanchi-Tongshu Capsule
- Where
- China
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pharmaceutical Factory of Chengdu HuaSun Group Inc., Ltd.
Autism Spectrum Disorder (ASD)
Non-Helium Magnetoencephalography in Autism Spectrum Disorder
The goal of this observational study is to learn how brain activity in children with autism spectrum disorder (ASD) differs from typical developing children using magnetoencephalography (MEG).
- Trial name
- NCT07064967
- Testing
- Magnetoencephalography
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Covid19, Pregnancy Related
Evaluation of COVID-19 IgG Antibodies in Maternal and Cord Blood Samples
Protocol Summary Study design: Prospective cohort study of pregnant COVID-19 positive patients at delivery. Study Objective: To collect umbilical cord blood and placenta samples at the time of delivery in COVID-19 positive women…
- Conditions
- Covid19, Pregnancy Related, Antibody Response
- Trial name
- NCT04732767
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
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