Clinical trials: Clinical Study
Age-associated Memory Impairment
Effect of BrainPhyt High Dose on Cognitive Function in Healthy Older Individuals
The purpose of this study is to evaluate if BrainPhyt, a microalgae based ingredient may affect cognitive function parameters in older healthy individuals with evidence of age-related cognitive decline.
- Trial name
- PHAEO-FOUR (NCT05759910)
- Testing
- Brainphyt high dose
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Microphyt
Induced Pluripotent Stem Cells
Blood Collection From Healthy Volunteers and Patients for the Production of Clinical Grade Induced Pluripotent Stem Cell (iPSC) Products
Background: Pluripotent stem cells are cells that can be converted to any type of cell (muscle, nerve, liver, etc.). Researchers are collecting blood samples to develop way to make a special cell product called induced…
- Trial name
- NCT02056613
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy Male Subjects
A Study in Healthy Male Subjects to Investigate the Comparability of Pharmacokinetics of the Fixed-Dose Combination of Pertuzumab and Trastuzumab Administered Subcutaneously Using a Handheld Syringe or Using the On-Body Delivery System
This is a randomized, open-label, 2-arm, parallel-group, single-dose, multi-center study in healthy male subjects to investigate the comparability of the pharmacokinetics of the fixed-dose combination of pertuzumab and…
- Trial name
- NCT05275010
- Testing
- Fixed-Dose Combination of Pertuzumab and Trastuzumab SC (PH FDC SC), Handheld Syringe with Hypodermic Needle, On-Body Delivery System
- Where
- 5 sites in Australia, New Zealand
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Pregnancy
Late Pregnancy Sample Collection Study
This study will obtain daily urine samples from pregnant volunteers, from 36 weeks pregnant until birth. All urine samples will be stored and used for research or product validation purposes.
- Trial name
- NCT04010682
- Testing
- urine sample collection
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Restless Legs Syndrome (RLS)
Study on the Mechanism of Gut Microbiota Mediating Restless Legs Syndrome Through Iron Metabolism
The goal of this observational study is to collect fecal and serum samples from patients with restless legs syndrome (RLS) and healthy controls for differential microbiota analysis to identify key bacterial species involved in…
- Trial name
- NCT07307482
- Testing
- Not applicable- observational study
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wenxia Jiang
Dry Eye
A Single Center, Open-Label Study to Evaluate the Ability of the TearScience™ LipiView™ II Ocular Surface Interferometer and the Keratograph® 5M to Detect Tear Film Stability Utilizing Miebo®
A study to investigate the ability of the TearScience™ LipiView™ II Ocular Surface Interferometer and the Keratograph® 5M to detect tear film stability utilizing Miebo®
- Trial name
- TFSTAB (NCT07722624)
- Testing
- Determine the ability of the TearScience™ LipiView™ II Ocular Surface Interferometer and the Keratograph® 5M to detect tear film stability utilizing Miebo®
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Eye Care Institute
Immunocompromised, Transplanted
Seasonal Flu Vaccine in Adult Transplant Recipients
The trial investigates the efficacy of adjuvanted seasonal influenza including H1N1 Fluad (R) in immunocompromised adults who have undergone solid organ or bone marrow transplantation.
- Trial name
- Fluad Tx (NCT01258023)
- Testing
- Fluad 1x
- Where
- Germany
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- HepNet Study House, German Liverfoundation
Gestational Diabetes
Impact of Blood Glucose at the First Trimester of Pregnant Women With Gestational Diabetes on Maternal and Fetal Outcomes and Metabolic Disorders: a Multi-central Prospective Cohort Study
The study is to investigate the impact of blood glucose management at the first trimester of pregnant women with gestational diabetes on the maternal and fetal outcomes and metabolic disorder.
- Trial name
- NCT01833559
- Testing
- Dietary control, Insulin
- Where
- China
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Healthy Women, Female Contraception
A Study to Evaluate the PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception
This is a Phase I multicenter, open-label, dose-ranging, three-dose PK and PD study of injectable LB administered as an IM or SQ injection at 40 mg, and subsequently at 50mg SQ and then 60 mg SQ depending on the preliminary…
- Trial name
- NCT04143659
- Testing
- levonorgestrel butanoate (LB) injection
- Where
- 7 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Premier Research
Nodular Basal Cell Carcinoma
Er:YAG Ablative Fractional Laser Assisted-Photodynamic Therapy Versus Photodynamic Therapy for Basal Cell Carcinoma
Topical photodynamic therapy with methyl-aminolaevulinate (MAL-PDT) has been introduced as an alternatively attractive procedure for BCC.
- Trial name
- NCT02018679
- Testing
- Er:YAG AFL-PDT, MAL-PDT
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dong-A University
Exercise
Smartphone-Based Use of Phonocardiography Technique for Estimating Heart Rate and Heart Rate Variability: Performance Study
This study aims to investigate the use of heart sound recordings, or phonocardiograms, recorded with smartphones' built-in microphones and accessory microphones to estimate heart rate (HR) and heart rate variability (HRV).
- Trial name
- NCT06848179
- Testing
- Computer algorithms, Exercise
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pneumococcal Disease
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
The purpose of this study is to learn about the safety of a new pneumococcal vaccine and how the new pneumococcal vaccine helps to fight against germs that can cause pneumonia (lung infections), meningitis (brain infections), and…
- Trial name
- NCT07573462
- Testing
- PG4, 20-valent pneumococcal conjugate vaccine (20vPnC)
- Where
- 78 sites in United States, Argentina and 8 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of a Single Oral Dose of BI 1026706 in Healthy Male Subjects
The primary objective of this trial is to investigate the effect of multiple doses of itraconazole on the pharmacokinetics of BI 1026706 given as single dose.
- Trial name
- NCT02513446
- Testing
- BI 1026706, Itraconazole
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Chronic Myeloid Leukemia (CML)
Study of CD38 and CD56 in Chronic Myeloid Leukemia
Chronic myeloid leukemia is a myelo-proliferative neoplasm characterized by abnormal proliferation of myeloid cells. There is an accumulation of mature granulocytes in the blood and bone marrow.
- Trial name
- NCT07740603
- Testing
- cd 38 and cd 56
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Spinal Cord Compression
White Matter Fiber Tracking and Assessment of White Matter Integrity in the Cervical Spinal Cord
White matter fiber tracking may provide a novel tool to assess the integrity of injured motor tracts in the cervical spine. It provides information about fiber directions which is not given by conventional MRI.
- Trial name
- NCT00280306
- Testing
- No interventions
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Glomerular Filtration Rate
Evaluation of Protein Loading on Measurement of Renal Reserve
The goal of this clinical trial is to evaluate the effect of protein loading on the measurement of renal reserve using the MediBeacon Transdermal glomerular filtration rate (tGFR) system.
- Trial name
- NCT07335614
- Testing
- Lumitrace, MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Assay Muscle, Liver Glutathione in Healthy Human
Non-invasive Quantification of Muscle and Liver Glutathione GSH-MRS
Glutathione (glutamyl-cysteinyl-glycine) is the main intracellular compound. It participates also in the detoxification of electrophiles molecules of which paracetamol.
- Trial name
- NCT02662816
- Testing
- Proton magnetic resonance spectroscopy (1H MRS), a protein rich breakfast at home, a protein rich lunch at the Clinical Investigation Center
- Where
- France
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Oxidative Stress, Inflammation
Milk and Soured Milk (filmjölk) Intervention on Oxidative Stress and Inflammation
This study evaluates a high intake of milk compared with a high intake of soured milk (Swedish filmjölk) on markers of oxidative stress and inflammation in a randomized crossover intervention study.
- Trial name
- NCT03821116
- Testing
- Milk, Soured milk (filmjölk)
- Where
- Sweden
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Muscle Tightness
Enhanced External Counterpulsation on Delayed Onset Muscle Soreness
This study will evaluate the effects of Enhanced External Counterpulsation on delayed onset muscle soreness. The primary outcomes will be duration of delayed onset muscle soreness, WBC count, CRP count, CPK count, and pain…
- Trial name
- NCT02175316
- Testing
- Enhanced External Counterpulsation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Nasal Septum; Deviation, Nasal Septal Srur
Outcomes of PRF on Septoplasty in Patient With Nasal Septal Deviation
The aim of this study is to assess the effectiveness of Platelet-Rich Fibrin (PRF) in improving postoperative healing, reducing complications, and enhancing functional outcomes in patients undergoing septoplasty
- Trial name
- NCT06996106
- Testing
- Effect of Platelet Rich Fibrin on Septoplasty
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
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