Clinical trials: Clinical Study
Cardiomyopathy, Dilated, Prognosis
Cardiac Magnetic Resonance-Clinical Prediction Model-Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is a common and serious heart disease characterized by left ventricular enlargement and impaired pumping function, with adverse prognosis (including heart failure, arrhythmia, heart-related…
- Conditions
- Cardiomyopathy, Dilated, Prognosis, Magnetic Resonance Imaging, Cardiac, Death, Sudden, Cardiac
- Trial name
- MPS-CMR-DCM (NCT07527715)
- Testing
- left ventricular ejection fraction
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Primary Biliary Cholangitis
A Study of the Pharmacokinetics and Safety of CS0159 in Subjects With Hepatic Injury
Phase I Study of the Pharmacokinetics and Safety of CS0159 in Subjects With Hepatic Injury
- Trial name
- NCT06888115
- Testing
- CS0159
- Where
- 3 sites in China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cascade Pharmaceuticals, Inc
Infertility, Female
Melatonin Study Between Diminished and Normal Responder in IVF
Poor sleep quality may lead to increase in oxidative stress and free radicals which in turn may decrease the reproductive function.
- Trial name
- NCT03117725
- Testing
- Melatonin adminstration
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Vibrio Cholerae
A Study to Evaluate Safety and Immunogenicity of the Bivalent Killed Whole Cell Oral Cholera Vaccine in Adults and Children
The purpose of this study is to determine whether the killed bivalent (O1 and O139)whole cell oral cholera vaccine(Shanchol™) is safe and effective in the treatment of Vibrio cholerae.
- Trial name
- NCT00760825
- Testing
- killed bivalent (O1 and O139)whole cell oral cholera vaccine
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Pregnancy Related, Diet Modification
Motivational Interviewing for Getting Healthy TodaY Study
The present study aims to test and rigorously evaluate the effectiveness of a computer-assisted motivational interviewing (CAMI) intervention that has already been shown to be successful with young women by reducing the risk of…
- Trial name
- MIGHTY (NCT03410225)
- Testing
- CAMI-TPP, CAMI-Fitness
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Columbia University
Covid19
Covid-19 Virtual Recovery Study
The purpose of this study is to determine the effects of respiratory muscle training (RMT) and nasal breathing on patients who have been infected with the SARS-CoV2 virus and continue to have lingering symptoms.
- Trial name
- NCT04950725
- Testing
- Strength RMT, Strength RMT and nasal breathing, Endurance RMT
- Where
- United States
- Volunteers
- 2,268 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
General Adult Population, Age 16 and Older
Norwegian Translation of the Things You Do Questionnaire 15-Item Version
Psychotherapy aims to modify dysfunctional patterns of thinking, feeling, and behaving to improve mental health. A five-factor model of adaptive behaviors, operationalized in the Things You Do Questionnaire (TYDQ), has been…
- Trial name
- TYDQ-15 (NCT06908525)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Dental Implants, Immediate Implant Placement
Autologous Demineralized Dentin Graft With or Without Melatonin for Immediate Implant Osseointegration
This randomized clinical study aims to evaluate the effect of autologous demineralized dentin graft (ADDG) with or without melatonin gel on the osseointegration of immediately placed dental implants in the maxillary premolar…
- Conditions
- Dental Implants, Immediate Implant Placement, Osseointegration
- Trial name
- NCT07610876
- Testing
- Autologous Demineralized Dentin Graft, Melatonin gel
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Hailey Hailey Disease
Efficacy of Guselkumab in Treating Hailey Hailey Disease
Hailey-Hailey disease (HHD) is a debilitating genetic skin disorder, affecting mainly body folds with erythema and painful erosions and blisters.
- Trial name
- NCT06651489
- Testing
- Guselkumab
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity
Lifestyle Intervention for Toddlers Pilot Study
Study aims to pilot a family-centred tailored nutrition intervention at child welfare clinics, targeting the previously observed dietary defaults of Finnish children.
- Trial name
- LIFT (NCT01204489)
- Testing
- Intensified dietary counseling at child wellfare clinics.
- Where
- Finland
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Pharmacokinetic
Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol)
This was a single center, open-label, two-way crossover, drug-drug-interaction study to determine the effect of multiple dosing of omeprazole on 4 consecutive days on the pharmacokinetics of a single dose of an immediate-release…
- Trial name
- NCT03979989
- Testing
- Tapentadol IR capsule, Omeprazole capsule
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Health Adults, Asthma
Study of HXN-1013 in Healthy Participants and Participants With Mild-to-Moderate Asthma
This is a Phase I, randomized, double-blind, placebo-controlled, single ascending dose study evaluating HXN-1013 in healthy participants and participants with mild-to-moderate asthma.
- Trial name
- NCT07900568
- Testing
- HXN-1013
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Helixon Biotechnology (Suzhou) Co., Ltd
Myopia
Silicone Hydrogel Soft Contact Lens 7-Day Extended Wear Basis
The objective of this study is to evaluate the safety and effectiveness of the Bausch + Lomb samfilcon A soft (hydrophilic) contact lens, a new silicone hydrogel contact lens, compared to the Bausch + Lomb PureVision® soft…
- Trial name
- NCT02939950
- Testing
- Bausch + Lomb Samfilcon A Soft Contact Lens, Bausch + Lomb Pure Vision Soft Contact Lens
- Where
- United States
- Volunteers
- 816 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Dependence, Perioperative/Postoperative Complications
Impact of Functional Status on 30-day Resource Utilization and Organ System Complications Following Bariatric Surgery
The goal of this observational study is to assess the effect of functional status on bariatric surgical thirty-day outcomes. The main questions it aims to answer are: Is functional status associated with higher incidence of…
- Conditions
- Dependence, Perioperative/Postoperative Complications, Frailty
- Trial name
- NCT05917691
- Testing
- Bariatric surgery, General anesthetic, Indeterminate
- Volunteers
- 65,627 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Psychosis
To Demonstrate the Relative Bioequivalency of Generic Haloperidol Tablets Versus Haldol in Normal Volunteers
To demonstrate the relative bioequivalency of generic Haloperidol tablets versus Haldol in normal volunteers.
- Trial name
- NCT00946491
- Testing
- Haloperidol 10 mg Tablets (Cord Laboratories), Haldol 10 mg Tablets (McNeil Pharmaceuticals)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sandoz
Memory Impairment
Memory and Exercise Training Study in Older Adults With Subjective Memory Complaints
This pilot study is a first step in a rapidly growing area of clinical research to create the most effective means to combat age-related losses in cognitive function through preventive lifestyle strategies such as physical…
- Trial name
- MET (NCT02433691)
- Testing
- simultaneous aerobic exercise, sequential aerobic exercise, stretching and toning
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- David Merrill, MD, PhD
Heart Failure With Preserved Ejection Fraction, Microvascular Angina
Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study
This is an observational study of Neuregulin-1 (NRG-1) plasma levels in patients with different forms of cardiovascular disease including microvascular angina (MVA), heart failure with preserved ejection fraction (HFpEF), as well…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Microvascular Angina, Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction
- Trial name
- NRG-1-CVDs (NCT04391491)
- Testing
- Neuregulin-1β level in plasma
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Influenza, Human
Safety and Immunogenicity First-in-human Dose-ranging Study of Self-Amplifying RNA Seasonal Influenza Vaccine in Adults
This is a safety and Immunogenicity first-in-human dose-ranging study of self-amplifying RNA Seasonal Influenza Vaccine (ARCT-2138) in adults.
- Trial name
- NCT06125691
- Testing
- ARCT-2138, Licensed Quadrivalent Vaccine for younger adults, Licensed Quadrivalent Vaccine for older adults
- Where
- 2 sites in Australia
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Arcturus Therapeutics, Inc.
Schizophrenia
Comparing the Effects of Sertindole and Olanzapine on Cognition (SEROLA)
Cognition is one of the core symptoms of schizophrenia. This study is a head-to-head trial between olanzapine and sertindole with cognition as primary outcome.
- Trial name
- SEROLA (NCT00885690)
- Testing
- Sertindole, Olanzapine
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy
Pharmacokinetic Drug Interaction Between Revaprazan and Itopride HCl in Healthy Male Subjects
To evaluate drug-drug interaction
- Trial name
- NCT01332890
- Testing
- Sequence 1, Sequence 2, Sequence 3
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.