Clinical trials: Clinical Study
Healthy Subjects
A Study of IBI351 in Healthy Subjects
This is a randomized, open-label, two-cycle clinical study to evaluate the drug interaction, food effect and pharmacokinetics of IBI351 and esomeprazole in healthy subjects.
- Trial name
- NCT05688124
- Testing
- IBI351, Esomeprazole
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Diastasis Recti
Evaluation of the Long-term Stability of Sheath Plication Using Absorbable Sutures in Patients With Diastasis of the Recti Muscles: an Ultrasonography Study
A comparative prospective study assessing the outcomes of recti muscle diastasis correction with absorbable suture.
- Trial name
- NCT01586559
- Where
- Czechia
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Bulovka Hospital
COVID-19
A Phase 1 Study of Human Monoclonal Antibodies, BRII-196 and BRII-198
This is a phase 1 study in which healthy adult volunteers will receive BRII-196/BRII-198 or placebo and will be assessed for safety, tolerability, and pharmacokinetics.
- Trial name
- NCT04691180
- Testing
- BRII-196 and BRII-198
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Brii Biosciences Limited
Hip Fractures, Elderly
Patient Reported Experience Measures Following Hip Fracture Surgery in the Elderly
With an ageing population, hip fractures are likely to become a significant public health burden. Hip fracture surgery is associated with significant morbidity and mortality.
- Conditions
- Hip Fractures, Elderly, Emergency Surgery
- Trial name
- NCT02842996
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Major Depressive Disorder
Relative Bioavailability (RBA) Study of LY03005 vs Pristiq®
The objective of this study is to evaluate relative bioavailability between 80 mg LY03005 oral tablets and 50 mg Pristiq® oral tablets after a single dose of each drug in a cross-over 2-period design under fasting condition in…
- Trial name
- NCT03357796
- Testing
- LY03005, Pristiq
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Healthy
A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults
The primary objectives of this study are to determine the effect of multiple doses of itraconazole on the single dose PK of ALXN2080, to determine the effect of multiple doses of fluconazole on the single dose PK of ALXN2080…
- Trial name
- NCT06173596
- Testing
- ALXN2080, Itraconazole, Fluconazole (AxMP)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexion Pharmaceuticals, Inc.
Endometriosis
BAY2328065 Single Dose Escalation, Safety and Tolerability, Pharmacokinetics, Relative Bioavailability, Food Effect
This single center, double-blind, randomized study with up to 11 treatment groups evaluates the safety and tolerability, pharmacokinetics, relative bioavailability and food effect of single ascending doses of BAY2328065
- Trial name
- NCT03427788
- Testing
- BAY2328065
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bayer
Diaper Dermatitis
Effect of Breast Milk on Diaper Dermatitis in Infants
Diaper dermatitis, one of infants' most common health problems, can be treated with various methods. One of these methods is breast milk.
- Trial name
- dermatit (NCT06699303)
- Testing
- Use of diaper rash cream containing Hamamelis virginiana (potency 12mg/100g) 5.35 g / 100 g for infants in the control group in diaper dermatitis care
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Chronic Obstructive Airway Disease
Pulmonary Disease in a Psychiatric Inpatient Population
Purpose: Patients with mental health disorders have a reduced life expectancy, compared to the general population. The shorter life expectancy is caused by natural and unnatural death.
- Trial name
- NCT01823627
- Testing
- Spirometry with reversibility test
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Psykiatrien Syd
Microbial Community in Breast Milk
Microbial Composition of Breast Milk Collected From Healthy Turkish Women
Breast milk is an optimal source of nutrients for newborns as well as a potential source of bacteria for the intestinal microbiota.
- Trial name
- NCT04072627
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cataract, Astigmatism
Post-Approval Study of the TECNIS® Toric Extended Cylinder Range Intraocular Lens (IOL)
This study is a prospective, multicenter, bilateral, non-randomized, open-label, clinical study conducted at up to 20 sites in the USA.
- Trial name
- NCT02649842
- Testing
- TECNIS Toric Models ZCT450, ZCT525 or ZCT600
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Infection, Human Immunodeficiency Virus
Phase 1, Open Label, Two Arm, Fixed Sequence Study to Evaluate the Effect of Rifampin and Rifabutin on GSK1349572 Pharmacokinetics in Healthy Male and Female Volunteers
This study will be a phase I, open label, two arm, fixed sequence crossover study to investigate the effect of rifampin and rifabutin on the steady state pharmacokinetics (PK) of GSK1349572 and the safety and tolerability of…
- Trial name
- NCT01231542
- Testing
- GSK1349572, Rifampin, Rifabutin
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Influenza
ADITEC FLU STUDY: Understanding the Genetic Basis for Immune Responses
Infants and young children do not respond as well as adults to the flu vaccines currently available in the UK. Fluad, is a different type of influenza vaccine that has been available in the European continent for the last decade…
- Trial name
- NCT01682369
- Testing
- TIV (Aggripal), ATIV (Fluad)
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Complete Placenta Previa
Efficacy Study of Random Placenta Margin Incision to Treat Complete Placenta Previa
The purpose of this study is to assess the efficacy of random placenta margin incision for hemorrhage control during cesarean section of complete placenta previa pregnancies.
- Trial name
- NCT02695069
- Testing
- Random Placenta Margin Incision
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Caries
Clinical Evaluation of SI-R21204 Versus Nano-hybrid Resin Composite: A Prospective Controlled Clinical Trial
Despite the advances in adhesive restorative techniques and materials, dental caries still remains a critical concern even today.
- Trial name
- NCT02823769
- Testing
- SI-R21204 resin composite, Nanohybrid resin composite
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Healthy Volunteers
A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Intravenous Doses of NH302 Injection in Healthy Participants
This is a first-in-human study of NH302 injection in healthy participants. The study will test single intravenous doses of NH302 to evaluate its safety and tolerability, how the body processes NH302, and its effects on selected…
- Trial name
- NCT07892469
- Testing
- NH302 injection
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Healthy
Safety, Tolerability, Pharmacokinetics of Intravenous FL058 and Meropenem in Healthy Subjects(SAD/MAD)
Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of FL058 and Meropenem Alone and in Combination following Single and Multiple Doses in Healthy Adult Subjects.
- Trial name
- NCT05058105
- Testing
- FL058 500mg and Meropenem 1000mg（ IV 120min）, FL058 1000mg（ IV 120min）, Meropenem 1000 mg （ IV 120min）
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Acne Vulgaris
Pilot Study of Tolerability and Effectivity of Two Combination Topical Acne Products
Study to compare two gels that are used to treat acne vulgaris. It will be compared the tolerability and effectivity following application of two combination topical acne products clindamycin 1% and 0.025% tretinoin gel (Acnatac®…
- Trial name
- PREFECT (NCT02731105)
- Testing
- Acnatac® Gel left face, Epiduo® Gel right face, Acnatac® Gel right face
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- GWT-TUD GmbH
Postmenopausal Osteoporosis, Compliance
Clinical Study of Raloxifene and Strontium Ranelate in Postmenopausal Osteoporosis
The purpose of this study was to compare compliance and efficacy of raloxifene and strontium ranelate in a group of women with postmenopausal osteoporosis.
- Trial name
- NCT01544894
- Testing
- Raloxifene, Strontium ranelate
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Prostate Cancer, Liver Cancer
Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies
This study aims to provide long-term follow-up care of patients previously enrolled in a vaccine study that involved poxviral vectors.
- Conditions
- Prostate Cancer, Liver Cancer, Breast Cancer, Colon Cancer
- Trial name
- NCT00451022
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
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