Clinical trials: Clinical Study - RCT
Cardiovascular Disease
Feasibility and Usability of a Pedometer in a Cardiovascular Disease Prevention Program for French-speaking Canadians
The purpose of this prospective randomized controlled trial (RCT) is to evaluate the feasibility and usability of a commercial pedometer and web application in a case-managed home-based Cardiovascular disease prevention and…
- Trial name
- PiezoRx (NCT02837471)
- Testing
- PiezoRx medical grade pedometer
- Where
- 2 sites in Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Alveolar Bone Resorption
Vertical GBR LPRF Block vs. Autogenous Bone With DBBM
split-mouth RCT, 25 months follow up. GBR protocol with LPRF as grafting material in the test group and autogenous bone with DBBM as grafting material in the control group.
- Trial name
- NCT06317090
- Testing
- guided bone regeneration
- Where
- Belgium
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Dental Anxiety
Comparing Binaural Beats and 432Hz Music for Reduction of Preoperative Anxiety in Root Canal Patients
Many patients suffer from dental anxiety and don't go to dentists for regular checkups. This can lead to the initiation and progression of dental caries, which, if not controlled at the right time, can lead to the loss of the…
- Trial name
- NCT06349200
- Testing
- 432 Hz music, Binaural beats, White noise
- Where
- Pakistan
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Insufficient Breastmilk Production
Effectiveness of Domperidone to Increase Breastmilk Supply in Mothers With Low Supply
This study is testing if a medication called domperidone will help women produce more milk so that they can keep breastfeeding and not use formula.
- Trial name
- NCT00284024
- Testing
- domperidone
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Inflammatory Bowel Diseases, Ulcerative Colitis
Personalized B-fructan Diet in Inflammatory Bowel Disease Patients
This study aims to examine patient tolerability of personalized dietary fibre consumption recommendations (high-pectin diet versus high-B-fructan diet based on personalized responses), provided by an IBD dietician, based on our…
- Trial name
- NCT05615779
- Testing
- Randomized B-fructan diet, Personalized pectin diet, Personalized B-fructan diet
- Where
- 2 sites in Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Chronic Pain
The Thrive Study: Improving Multimodal Physical Function in Adults With Heterogenous Chronic Pain
The investigators aim to conduct a randomized controlled trial to test the feasibility of a mind-body walking program compared to a health education program for individuals with chronic musculoskeletal pain.
- Trial name
- NCT05700383
- Testing
- GetActive-Fitbit, Healthy Living for Pain
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Decay, Dental, Caries Class II
Clinical Performance of Short Fiber Reinforced Flowable Resin Composite Restorations 2y RCT
Clinical performance of short fiber reinforced flowable resin composite restorations versus conventional resin composite restorations will be tested in posterior teeth (2y randomized clinical trial).
- Trial name
- NCT04720638
- Testing
- Short fiber reinforced flowable resin composite restorations, Conventional resin composite restoration
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Visual Processing Speed
Iowa Healthy and Active Minds Study
This is second-generation study based on results from ACTIVE (Advanced Cognitive Training for Independent and Vital Elderly). This four-arm study is known as IHAMS (the Iowa Healthy and Active Minds Study).
- Trial name
- IHAMS (NCT01165463)
- Testing
- SOPT basic training, Crossword Puzzles, SOPT booster training
- Where
- United States
- Volunteers
- 681 people, healthy volunteers welcome
- Sponsor
- Fredric D Wolinsky
Patient-centered Care
Impact of a Wellness Portal on The Delivery of Patient-Centered Preventive Care
Building upon our experience with a very sophisticated preventive services prompt and reminder system, the Preventive Services Reminder System (PSRS), the investigators propose to conduct a systematic three-year study with the…
- Trial name
- NCT01520662
- Testing
- Implementation of a secure web-based patient Wellness Portal
- Where
- United States
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Twin Pregnancy, Antepartum Condition or Complication
Effects of ACS in Twin With LPB: Study Protocol for a RCT
This study will be the first study that evaluates the effectiveness of antenatal corticosteroid (ACS) in late preterm twin neonates.
- Trial name
- NCT03547791
- Testing
- Betamethason Sodium Phosphate, Normal saline
- Where
- South Korea
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Stress Reaction, Sexuality
Effects of Self-Compassion Practice on Stress Reactivity Among Sexual Minority Women
This project will test the ability of brief self-compassion training to attenuate physiological and subjective responses to induced stress among sexual minority women, transgender people, and nonbinary people.
- Conditions
- Stress Reaction, Sexuality, Compassion
- Trial name
- NCT05949060
- Testing
- Compassion Intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Clinical Study - RCT
Paraspinal Stimulation in Treating MPS
To test the hypothesis that the effect of either multiple deep intramuscular stimulation therapy [(DIMMST: trigger point deep dry needling (TrP-DDN) is combined with paraspinal deep intramuscular stimulation (PDIMS) and needle…
- Trial name
- DIMMST (NCT01708343)
- Testing
- DIMMST
- Where
- 3 sites in Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Sustainable Nutrition, Sustainable Healthy Diet
Behavior Development Training for Sustainable Nutrition
The European Federation of Dietetic Associations (EFAD) recommends sustainable nutrition to create healthy societies. Sustainable nutrition models include the Mediterranean diet, vegetarian and vegan diets, the double pyramid…
- Conditions
- Sustainable Nutrition, Sustainable Healthy Diet, Sustainable Food Consumption, Sustainable Lifestyles
- Trial name
- RCT (NCT07090993)
- Testing
- sustainable nutrition education
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Betul Uner
Alcohol Drinking, Sexual Violence
Motivations, Attitudes, and Perceptions Study
The goal of this clinical trial is to compare the impact of providing participants with 1. A recently developed protocol for motivating bystanders to intervene to help others who are in sexual risk situations…
- Conditions
- Alcohol Drinking, Sexual Violence, Social Norms
- Trial name
- MAP (NCT05873413)
- Testing
- Motivate-the-Bystander, Motivate-the-Bystander+Alcohol, Attention-only Control
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Coronary Syndrome, Acute, Coronary Artery Disease
A Study of Population and Sex-specific Troponin Cutoffs for Ruling Out Acute Myocardial Infarction
Acute myocardial infarction (MI) is defined as a rise and/or fall in cardiac troponins (cTn) with at least one value above the 99th percentile upper reference limit (URL) in the context of symptoms or clinical evidence of…
- Conditions
- Coronary Syndrome, Acute, Coronary Artery Disease, Myocardial Infarction
- Trial name
- DANSPOT (NCT05336435)
- Testing
- Implementation of the new population and sex-specific 99th percentile URL for cardiac troponin
- Where
- 22 sites in Denmark
- Volunteers
- 5,175 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Musculoskeletal Diseases or Conditions
Wadey RCT MSK Short Case Simulations With FMED
Study Agent/ Intervention/ Procedure The educational tool consisted of 20 short (MSK) case simulations of 15 minutes duration reflecting conditions of the upper extremity; lower extremity; spine; trauma and MSK infections were…
- Trial name
- NCT05914922
- Testing
- Educational Tool
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Physical Activity, Sedentary Lifestyle
The PACO RCT Study
The aim of this school-based cycling intervention called "Cycling and Walk to School" (PACO, for its Spanish acronym) will be to examine their effects on adolescent's cycling to and from school and physical activity (PA).
- Conditions
- Physical Activity, Sedentary Lifestyle, Behavior
- Trial name
- PACO (NCT03937336)
- Testing
- Bike Intervention Group
- Where
- Spain
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Stress, Psychological, Occupational, Stress, Psychological
Self-Help Plus (SH+) for Stress Reduction in Social Service Workers: A Pilot RCT
This is a two-arm, stratified cluster-randomized controlled pilot trial evaluating the feasibility and preliminary effectiveness of the World Health Organization's Self-Help Plus (SH+) intervention for stress reduction among…
- Conditions
- Stress, Psychological, Occupational, Stress, Psychological, Psychological Distress, Burnout, Professional
- Trial name
- NCT07644949
- Testing
- Self-Help Plus (SH+), Enhanced Care as Usual (ECAU)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Skin Cancer
Prospective, RCT of Split Thickness Skin Grafts on Lower Leg After Compression Therapy With Compression Bandage vs. NPWT
The single center, prospective, randomized trial includes in total 60 patients. We want to compare two different treatment methods for compression therapy for split thickness skin graft in lower leg.
- Trial name
- NCT03452852
- Testing
- PICO, Coban 2 lite
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Social Interaction, Quality of Life
A-Health RCT: Effects of Participatory Art-based Activity on Health of Older Community Dwellers
The overall objective of the study is to examine the effects of the Montreal Museum of Fine Arts (MMFA) participatory art-based activity on wellbeing, quality of life and health condition in older community dwellers.
- Conditions
- Social Interaction, Quality of Life, Health, Subjective
- Trial name
- A-Health-RCT (NCT03679715)
- Testing
- participatory art-based activity
- Where
- 2 sites in Canada, Japan
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital