Clinical trials: Clinical Study - RCT
Prelabour Rupture of Membranes at Term
A Pilot RCT on the Management of Term Prelabour Rupture of Membranes
This is a pilot study that will eventually result in a main randomised controlled trial that will look at what management is associated with a higher rate of normal birth and a lower rate of chorioamnionitis (maternal infection)…
- Trial name
- NCT02872883
- Testing
- Expectant management, Minimal Vaginal examinations (only when necessary), Active management
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Autism Spectrum Disorder, Parents
Virtual Reality Experiences as Tools to Support Mental Health in Parents of Children With Autism
Mindfulness is a technique that involves the intentional and non-judgmental regulation of attention to the present moment, with curiosity, openness, and acceptance, as per its definition.
- Trial name
- Mind-VR (NCT05852795)
- Testing
- Virtual Reality-mediated Mindfulness-Based Interventions, Virtual Reality-mediated Mindfulness-Based Interventions without audio guided experience
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Sexual Harassment, Anti-Gay Bias
Effectiveness Study of the Intervention "Stop Sexual Harassment" in Secondary School
"Stop sexual harassment" is a school based intervention tailored to reduce sexual- and gendered harassment among pupils in secondary school.
- Conditions
- Sexual Harassment, Anti-Gay Bias, Non Sexual Harassment, Gender-based Violence
- Trial name
- NCT04716400
- Testing
- Stop sexual harassment
- Where
- Norway
- Volunteers
- 2,037 people, healthy volunteers welcome
- Sponsor
- NORCE Norwegian Research Centre AS
Vitamin D Deficiency
Effect of Vitamin D-biofortified Eggs on Wintertime Serum 25-hydroxyvitamin D in Adults: Randomized Controlled Trial
While there have been a considerable number of studies on the impact of additional vitamin D in the diets of hens on the resulting egg vitamin D content, the effect of consumption of such vitamin D-enhanced eggs on vitamin D…
- Trial name
- EnhanceDeggs (NCT02678364)
- Testing
- Control eggs, Vitamin D3 eggs, 25-Hydroxyvitamin D3 eggs
- Where
- Ireland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University College Cork
Pelvic Organ Prolapse
Native Tissue Repair With Surgical Pelvic Organ Pessary - an RCT
This is an RCT looking at the primary outcome of composite success following anterior repair with native tissue at 6, 12, 24 months in two arms.
- Trial name
- NTRSPOP (NCT02808377)
- Testing
- Surgical Pelvic Organ Pessary
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Chronic Pain
The Thrive Study: Improving Multimodal Physical Function in Adults With Heterogenous Chronic Pain
The investigators aim to conduct a randomized controlled trial to test the feasibility of a mind-body walking program compared to a health education program for individuals with chronic musculoskeletal pain.
- Trial name
- NCT05700383
- Testing
- GetActive-Fitbit, Healthy Living for Pain
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Postoperative Pain
Feasibility Study on Pain Control After Laparoscopic Cholecystectomy
The objective of the study is to hopefully understand the most beneficial way to control pain after removing the gallbladder by keyhole surgery (laparoscopic cholecystectomy).
- Trial name
- NCT03532906
- Testing
- TAP Block, Control
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Gastric Cancer
The Effect of Post-operative Exercise in Gastric Cancer Patients: A Randomized Controlled Trial (RCT) Study
Medical advancements are enhancing the survival rates of individuals with gastric cancer. The growing population of gastric cancer survivors underscores the importance of managing treatment-related after-effects and side effects.
- Trial name
- NCT06260293
- Testing
- exercise
- Where
- South Korea
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Edentulous Alveolar Ridge, Soft Tissue Healing
Soft Tissue Integration of Different Abutment Surfaces
Objective of the present study was to assess the peri-implant soft tissue profiles between argon plasma pre-treated (PT) and non-treated (NPT) abutments by comparing clinical and histological parameters 2 months after abutment…
- Trial name
- NCT05821673
- Testing
- Argon plasma pre-treated abutment insertion, abutment insertion
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo
Health Behavior
HASCV-R" Health Programme: a RCT
The goal of this randomized controlled trial: is to determine the effect of " HASCV-R " health programme on the health promoting and protective behaviours of the women.
- Trial name
- NCT06439680
- Testing
- HASCV-R" Health Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bozok University
ECE Teachers Self Efficacy, Team Work
Power of Growth - Digitally Assisted Intervention for the Early Childhood Educators' Self-efficacy Teamwork and Children's Behavioral Challenges.
This is an RCT study investigating the efficacy of digital intervention focusing on enhancing positive directing skills for teams of early childhood education (ECE) professionals.
- Conditions
- ECE Teachers Self Efficacy, Team Work, Positive Pedagogy, Behavior Problems
- Trial name
- FinnPoG (NCT06856408)
- Testing
- FinnPog
- Where
- 2 sites in Finland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Turku
Overall Skin Appearance, Dry Skin; Eczema
RCT to Evaluate the Cosmetic Efficacy of Demo-cosmetic Active Ingredient CLS02021
This study will explore the potential of probiotic based, novel cosmetic active ingredient to rebuild the collagen based skin barrier with the overall aim to rejuvenate ageing or damaged skin, improve skin integrity, appearance…
- Trial name
- NCT05048121
- Testing
- Cosmetic Active Ingredient CLS02021
- Where
- 2 sites in Bosnia and Herzegovina
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Anbiome Labs LLC
Intracranial Aneurysm, CT Angiography
IDEAL Study: Blinded RCT for the Impact of AI Model for Cerebral Aneurysms Detection on Patients' Diagnosis and Outcomes
This study (IEDAL study) intends to prospectively enroll more than 6450 patients who will undergo head CT angiography (CTA) scanning in the outpatient clinic.
- Conditions
- Intracranial Aneurysm, CT Angiography, Deep Learning, Double Bind Interaction
- Trial name
- IDEAL (NCT06118840)
- Testing
- True-AI-integrated intracranial aneurysms diagnosis strategy
- Where
- 21 sites in China
- Volunteers
- 6,450 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Neuropathic Pain
Exploring the Role of the GABAergic Modulation in Pain Transmission in Human
Neuropathic pain affects about 7% of the general population in European countries. Meta-analyses indicate that only a minority of neuropathic pain patients has adequate response to drug therapy and management of neuropathic pain…
- Trial name
- NDMC-101 (NCT03375034)
- Testing
- NDMC 20mg, NDMC60mg, Clonazepam 1.5mg
- Where
- Switzerland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Jules Desmeules
Overweight and Obesity
ABUNDANCE of A NATURAL ODOUR in HUMAN CEREBROSPINAL FLUID AFTER OLFACTORY EXPOSURE - the OLFO-Brain Study
The goal of this clinical trial is to investigate the abundance of a natural odour in human cerebrospinal fluid in obese and lean participants after inhalation thereof.
- Trial name
- OLFO-Brain (NCT06370845)
- Testing
- Inhalation - Natural Odour
- Where
- 2 sites in Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Tolerance, Safety Issues
Buck Institute Ketone Ester RCT
This study is to investigate the tolerability and safety of a ketone promoting ingredient, called a ketone ester (KE), in healthy older adults.
- Conditions
- Tolerance, Safety Issues, Aging
- Trial name
- BIKE (NCT05585762)
- Testing
- Ketone ester
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Buck Institute for Research on Aging
Oral Health
Cluster RCT on the Effect of the Topics Number in Oral Health Educational Video Among Preschool Children.
Purpose: This cluster randomized controlled trials study aims to investigate whether different number of topics delivered through educational video affect the oral health status, knowledge, attitude and practice of preschool…
- Trial name
- NCT06073392
- Testing
- Educational video
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
COVID-19
COVID-19 Self-testing Study
The goal of this clinical trial is to understand how the introduction of an app-based intervention changes knowledge, attitudes, and practices on COVID-19 self-testing.
- Trial name
- NCT05701878
- Testing
- SMARTest mobile app for COVID-19 self-testing
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Colorectal Cancer
RCT of Air Insufflation Versus Water Infusion Colonoscopy by Supervised Trainees
Our aim is to perform a randomized-controlled trial comparing air insufflation sedated colonoscopy (conventional method) vs. water infusion sedated colonoscopy (study method) by supervised trainees.
- Trial name
- NCT00841282
- Testing
- Colonoscopy for colorectal cancer screening, Water Infusion Colonoscopy, Air insufflation colonoscopy
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- East Bay Institute for Research and Education
Myopia, Myopia, Progressive
Multicenter RCT: LED Red Light Dose-Response in Myopia Progression Control
The goal of this clinical trial is to verify the effectiveness and safety of non-laser LED red light combined with defocus lens therapy for controlling myopia progression and evaluate the impact of different intervention…
- Trial name
- NCT07330180
- Testing
- Yingtong Vision Rehabilitation Instrument, Hoya DIMS multi-point myopia defocus lens
- Where
- 7 sites in China
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine