Clinical trials: Clinical Study - RCT
Mental Health, Well-Being
MIELITEKO Lifestyle Intervention Study
Mental health problems cause individual, social and economic burden to the society. The mental health problems are among the highest levels in North Savo compared to the general Finnish population.
- Conditions
- Mental Health, Well-Being, Life Style
- Trial name
- MIELITEKO (NCT05377398)
- Testing
- Digital individual-level intervention (Bit Habit), Group-based healthy lifestyle and green power intervention, Individual-level healthy lifestyle intervention
- Where
- 5 sites in Finland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Autism Spectrum Disorder, Transition
Evaluating the Efficacy and Effectiveness of SCOPE - RCT
The study will entail an evaluation of the feasibility, acceptability, efficacy and effectiveness of SCOPE coach supported internet-delivered psychoeducative program using a randomized controlled design in a clinical health care…
- Trial name
- SCOPERCT (NCT03665363)
- Testing
- SCOPE, Self-study
- Where
- Sweden
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Twin Pregnancy, Antepartum Condition or Complication
Effects of ACS in Twin With LPB: Study Protocol for a RCT
This study will be the first study that evaluates the effectiveness of antenatal corticosteroid (ACS) in late preterm twin neonates.
- Trial name
- NCT03547791
- Testing
- Betamethason Sodium Phosphate, Normal saline
- Where
- South Korea
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Breast Cancer
Protocol for Women at Increased Risk of Developing Breast Cancer
To assess the effects of twelve months of celecoxib administration by evaluating breast tissue needle aspirations, to determine if cell growth can be slowed.
- Trial name
- NCT00291694
- Testing
- celecoxib
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Labor Pain
Transcutaneous Electrical Nerve Stimulation for Labor Pain Control
Transcutaneous electrical nerve stimulation (TENS) is a non-invasive electro-physical modality used for several pain conditions including labor pain control.
- Trial name
- NCT04894539
- Testing
- DS5 electrical stimulator
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Ridge Preservation, Bone Regeneration
Socket Preservation Procedure Studying Soft and Hard Tissue Outcomes
Two different surgical protocols for socket preservation were compared. Soft and hard tissue outcomes were measured clinically and radiographically at baseline and six months post operatively.
- Trial name
- NCT03497403
- Testing
- Socket preservation control, Socket preservation experimental
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Post-traumatic Stress Disorder
Program for Alleviating and Resolving Trauma and Stress 2
This pilot RCT will test the preliminary efficacy of an intensive group model of Internal Family Systems (IFS) called the Program for Alleviating and Resolving Trauma and Stress (PARTS) compared with a Nature-Based Stress…
- Trial name
- PARTS2 (NCT05095428)
- Testing
- PARTS Program, NBSR-T Program
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Gingival Recession, Root Planing
Gingival Recession Treatment Using Two Different Surgical Techniques
Coronally the advanced flap is considered a predictable treatment of gingival recession but in certain situations, it needs a filler like subperiosteal connective tissue graft (CTG) which is considered as the gold standard…
- Trial name
- NCT04966208
- Testing
- xenogeneic collagen matrix
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy
ECA-enhanced Document Explanation RCT
The investigators will evaluate a computer-animated character that explains medical illustrations to people, comparing the character to having people understand the illustrations on their own, and also comparing the computer…
- Trial name
- NCT06435819
- Testing
- Embodied Conversational Agent (ECA)
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Dyslipidemia
ABT-335 (Choline Fenofibrate) Reverse Cholesterol Transport (RCT) Study
The objectives of the study are: 1. To evaluate the effect of ABT-335 (choline fenofibrate) on several parameters of RCT (reverse cholesterol transport) in men and post-menopausal women diagnosed with dyslipidemia (i.e., low…
- Trial name
- NCT00673881
- Testing
- choline fenofibrate
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Radiant Research
Hip Arthroplasty
Rehabilitation to Patients Over 65 Years Undergoing THA
Patients over 65 years do not have a self care ability the surgery benefits them. The aim of this study is development of a rehabilitation program based on patients' self-rated health. 1.
- Trial name
- NCT00226070
- Testing
- interview and advising, 3 follow up interviews and personal advising, interview SF-36 self rated health
- Where
- 6 sites in Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Unexplained Infertility, Polycystic Ovarian Syndrome
Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
The main purpose of this study is to test the effectiveness of nimodipine in preventing a luteinizing hormone (LH) surge in women undergoing ovulation induction with clomiphene citrate.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Anovulatory
- Trial name
- NIMO (NCT01672801)
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston IVF
SARS-CoV Infection, Covid19
Use of Hypochlorous Acid as Prophylaxis in Health Personnel at High Risk of Infection by SARS-CoV 2 (COVID19)
The pandemic caused by SARS-CoV-2 is a global emergency present in 6 continents including 66 countries, incurring a shortage of effective and safe therapeutic alternatives that can contribute to reducing the risk of…
- Conditions
- SARS-CoV Infection, Covid19, Infection Viral
- Trial name
- NCT04684550
- Testing
- Stabilized hypochlorous acid
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital Universitario San Ignacio
Acne, Premenstrual Syndrome
An RCT Evaluating the Efficacy of a Skincare Routine and Acne Supplement on Improving Acne and Other Symptoms of PMS
This study aims to evaluate the efficacy of the MINDBODYSKIN Hormonal Acne Supplement and a prescribed skincare routine of 6 products on facial acne and on symptoms of PMS, compared to a skincare routine of 6 products alone.
- Trial name
- NCT06018168
- Testing
- Skincare Routine, MINDBODYSKIN Supplement
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clearstem Skincare
Healthy Elderly Individuals With High LDL-cholesterol or Risk of Cardiovascular Disease
Low- and Moderate-intensity Statin and Clinical Outcome of Primary Prevention in Individuals Aged >70 Years: the SCOPE-70 RCT Study
One of the most effective drug in the primary prevention of cardiovascular disease is statins. The protective effects of statin on developement of cardiovascular disease has been demonstrated in elderly individuals.
- Trial name
- NCT03770312
- Testing
- Low intensity statin, Moderate intensity statin
- Where
- South Korea
- Volunteers
- 724 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Apical Periodontitis, Chronic Kidney Diseases
Effects of RCT on Periapical Healing, Inflammatory Markers, and Kidney Function Indicators in CKD Patients With AP
The purpose of this prospective study is to determine the effect of non-surgical root canal treatment in chronic kidney disease patients and healthy patients with apical periodontitis.
- Trial name
- NCT06446011
- Testing
- root canal treatment in Ckd patients, root canal treatment in healthy patients
- Where
- India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pediatric Dentistry
Clinical Performance and Psychological Impact of Colored Restorations Cement in Primary Molars
Aim of the study The aim of the presented study is to evaluate: I- The clinical performance of flowable polyacid-modified composite resin 'compomer' and resin-modified glass-ionomer cement in prepared Class II cavities in primary…
- Trial name
- NCT05557682
- Testing
- composite restorative treatment
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Healthy Volunteers
Trial on Single/Multiple Ascending Doses for Safety, PK and PD for CBP-0276 in Healthy Subjects
A double-blind, randomized, placebo-controlled, single and multiple ascending dose study with food effect to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of CBP-0276.
- Trial name
- CBP276SADMAD (NCT07708831)
- Testing
- CBP-0276 Acetate
- Where
- 2 sites in Mexico
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Clarent Biopharma, Inc.
Mental Well-being, Happiness
Healthy Community Pilot Project RCT Study
Aims: To enhance mental well-being of adolescents, adults and their families by creating a positive, happy and joyful environment in the community. Targets: Adults aged 18-59 and their family members in Hong Kong.
- Trial name
- NCT03332810
- Testing
- SME family based physical activity, Gathering activity
- Where
- Hong Kong
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cervical Ripening, Induction of Labor
Heated Saline in Cervical Balloon for Labor Induction, a RCT
This study is a single-center, randomized, two-arm, controlled trial, including women requiring cervical ripening during the process Induction of Labor using Balloon catheter (BC).
- Conditions
- Cervical Ripening, Induction of Labor, Unfavorable Cervix, Mechanical Method
- Trial name
- NCT05864326
- Testing
- Warm group, Room temperature group
- Where
- Switzerland
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Begona Martinez de Tejada