Clinical trials: Clinical Supervision
Pain
A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone for Musculoskeletal Pain
Acute Pain is one of the most frequent chief complaints and the main reason for visiting the Emergency Department (ED). The acute pain in the ED is largely prevalent across the country with recent literature demonstrating that…
- Trial name
- NCT04860804
- Testing
- Aspirin and Ketamine, Oral Ketamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Antonios Likourezos
Atrial Fibrillation
Integrated Management Program Advancing Community Treatment of Atrial Fibrillation
Research Question: Among community-based patients with AF, does providing an integrated Clinical Decision Support System (CDSS) to providers and patients improve process of care and clinical outcomes, and decrease the healthcare…
- Trial name
- IMPACT-AF (NCT01927367)
- Testing
- Clinical Decision Support System for AF
- Where
- 2 sites in Canada
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- Jafna L Cox
Pre Eclampsia
Pilot Assessment of an Auto Blood Pressure Monitor
The purpose of the study is to help make a lower cost automatic blood pressure monitor device for diagnosis and monitoring of pre-eclampsia in pregnant women, where automatic blood pressure monitoring is limited or not available.
- Trial name
- NCT02258256
- Testing
- Sphygmo
- Where
- Malawi
- Volunteers
- 11 people
- Sponsor
- William Marsh Rice University
Arthritis Rheumatoid
This Study is to Investigate the Effect of Etanercept in Early Versus Delayed Referral for Management of Rheumatoid Arthritis Patients.
This study is to investigate the effect of etanercept in early versus delayed referral for management of rheumatoid arthritis patients assessing real-world patient data entered in the Iraq National Center of Rheumatology database…
- Trial name
- NCT04267614
- Testing
- Etanercept
- Where
- Iraq
- Volunteers
- 1,226 people
- Sponsor
- Pfizer
Obesity
Individualized Obesity Pharmacotherapy
The researchers are trying to identify the specific characteristics (phenotypes) that may be useful to help select the right medication for weight loss.
- Trial name
- NCT03374956
- Testing
- Phentermine-Topiramate, Liraglutide, Naltrexone/bupropion
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- Mayo Clinic
Eczema
Test to Determine the Effectiveness of Moisturizing Balm Used on Babies With Dry, Itchy Skin
The purpose of this 3 week study is to test the effectiveness of an over-the-counter (OTC) skin balm in infants and toddlers with mild to moderate dry, itchy skin.
- Trial name
- NCT02404493
- Testing
- EpiCeram Skin Barrier Emulsion, 1% Colloidal Oatmeal Balm
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Hypertension
Valsartan Intensified Primary Care Reduction of Blood Pressure Study
This study will assess the efficacy of an intensive blood pressure management strategy compared to usual care in a primary care (general practice) setting.
- Trial name
- VIPER-BP (NCT00902304)
- Testing
- Valsartan and hydrochlorothiazide (HCTZ) - monotherapy, Valsartan and amlodipine, Usual care
- Where
- 3 sites in United States, Australia
- Volunteers
- 2,337 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Kidney Diseases, Hypertension
Chronic Kidney Disease Clinical Decision Support
To prevent serious chronic kidney disease (CKD) complications such as end-stage renal disease and cardiovascular events, better strategies are needed to identify, treat, and refer CKD patients seen in primary care clinics.
- Conditions
- Chronic Kidney Diseases, Hypertension, Diabetes
- Trial name
- CKD-CDS (NCT03890588)
- Testing
- CKD enhanced clinical decision support
- Where
- United States
- Volunteers
- 6,295 people
- Sponsor
- HealthPartners Institute
Obstructive Sleep Apnea
Efficacy of the OrthoApnea NOA® Mandibular Advancement Device in the Management of Obstructive Sleep Apnea.
The objective of this study is to assess the efficacy of the Orthoapnea NOA® mandibular advancement device and describe the percentage of advancement (%) needed to reach efficacy, and to retrospectively compare with other MAD…
- Trial name
- NCT05139303
- Testing
- Orthoapnea NOA®
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Isabel Moreno Hay
Low Back Pain, Veterans Family
Improving Veteran Access to Integrated Management of Back Pain
The purpose and objective of this pragmatic trial is to examine the effectiveness of two different quality improvement care pathways for low back pain (LBP); a sequenced, integrated care pathway (ICP) and 2) a coordinated, care…
- Trial name
- AIM-BACK (NCT04411420)
- Testing
- Pain modulation with physical pain treatment, Telephone delivered self-management counseling for increasing physical activity, Telephone delivered behavioral treatment for participants with high risk for continued disability
- Where
- United States
- Volunteers
- 1,817 people
- Sponsor
- Duke University
Asthma
Non-Interventional Study to Describe the Clinical Management in Asthmatic Patients (NICMA)
Asthma is a heterogenic chronic disease that affects more than 300 million people worldwide, which it's characterized by acute symptomatic episodes of varying severity, including intermittently inflammation and narrowing of the…
- Trial name
- (NICMA) (NCT06811155)
- Where
- Spain
- Volunteers
- 288 people
- Sponsor
- Hospital Universitario Virgen de la Victoria
Schizophrenia, Schizoaffective Disorder
Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective Disorder
The study will compare the effectiveness of antipsychotic medications for patients with schizophrenia or schizoaffective disorder for whom a medication change may be indicated because of an increased risk of cardiovascular…
- Trial name
- CAMP (NCT00423878)
- Testing
- Risperidone, Olanzapine, Quetiapine
- Where
- 28 sites in United States
- Volunteers
- 215 people
- Sponsor
- National Institute of Mental Health (NIMH)
Carcinoma, Renal Cell
Treatment Patterns and Clinical Outcomes Among Patients With Advanced Renal Cell Carcinoma (aRCC) Receiving Systemic First-line (1st Line) Anti-cancer Treatment Under Daily Routine in Germany: Retrospective Medical Chart Review (RENALISTIC Study).
The purpose of this study is to learn about the treatments used in for advanced renal cell carcinoma as well as effectiveness of these treatments in the real world. Study participants must be: At least 18 years of age or older.
- Trial name
- NCT05534789
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Pfizer
Family Caregivers, Stroke
Caregiver Self-Management Needs Through Skill-Building
Caring for a family member after a stroke can be very difficult and worsen the physical and mental health of untrained caregivers.
- Trial name
- NCT03635151
- Testing
- Telephone Assessment and Skill-Building Kit (TASK III) Group, Information Support and Referral (ISR) Group
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
COPD, COPD Exacerbation Acute
ProAir Digihaler in COPD Disease Management: A Real World Study
A pilot study to explore the utilization of the TEVA ProAir Digihaler rescue medication use and inhalation parameters to identify disease deterioration to help in the management of COPD patients in clinical practice.
- Trial name
- NCT04821869
- Testing
- ProAir Digihaler, Digihaler
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Pulmonary Research Institute of Southeast Michigan
Pain, Postoperative
Safety and Clinical Utility Study of SSEC Fentanyl 40 mcg for Acute Post-op Pain Management in Pediatric Participants
The objective of this study is to evaluate the safety and clinical utility of the active, SSEC fentanyl 40 micrograms (mcg) for the management of acute, postoperative pain in pediatric participants.
- Trial name
- NCT02395653
- Testing
- fentanyl
- Where
- 10 sites in United States
- Volunteers
- 71 people
- Sponsor
- The Medicines Company
Surgery
Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI
The study goal is to establish the correlation of hemoglobin values determined by the noninvasive pulse oximetry-determined hemoglobin (SpHb) system with hemoglobin as measured by other validated devices.
- Trial name
- NCT02841397
- Testing
- Masimo Pulse CO-Oximeter
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Masimo Corporation
Diabetic Foot Ulcer, Deep Diabetic Foot Ulcer
Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers
Diabetes-related foot ulcers (DFUs) are a leading cause of hospitalization and amputation worldwide, and account for 33% of all direct costs of diabetes care in the US.
- Trial name
- NCT03476876
- Testing
- Dermacell, Integra
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Baylor College of Medicine
Migraine
Clinical Decision Support for Patient Migraine Management
Little is known about who adheres to migraine management strategies, and circumstances that enhance adherence. This knowledge is required to develop patient-level interventions to improve adherence to migraine management…
- Trial name
- CDST (NCT03706794)
- Testing
- Clinical Decision Support Tool, Headache Education
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albert Einstein College of Medicine
Obesity
A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in America
The purpose of this post approval pragmatic clinical study is to see how well semaglutide lowers body weight compared to other medication on the market used to treat obesity, across three US-based employers.
- Trial name
- NCT05579249
- Testing
- Semaglutide, Orlistat, Phentermine/Topiramate
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Novo Nordisk A/S