Clinical trials: Clomiphene Citrate
Polycystic Ovary Syndrome, Anovulation
LOD vs Gn in Anovulatory PCOs Resistant to First Line Agents
PCOS is a complex disease that is diagnosed by the presence of two of the following three: oligo/anovulation, clinical and/or biochemical hyperandrogenism, or polycystic ovaries by ultrasound .
- Trial name
- NCT04325295
- Testing
- Laparoscopic ovarian drilling, Recombinant FSH (rFSH)
- Volunteers
- 200 people
- Sponsor
- Assiut University
Infertility, Female
Effect of Clomiphene Citrate on Uterine Blood Fow in Women With Unexplained Delayed Conception
In a prospective observational study at a university teaching hospital, blood flow indices and serum hormone levels were compared between spontaneous and stimulated cycles in the same group of 50 patients with unexplained delayed…
- Trial name
- NCT03322852
- Testing
- Vascularization indices observation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Ovulation Disorder
Human Chorionic Gonadotrophin & Trigger
In women being treated with medicines to help eggs to grow (called ovulation induction), The investigators wish to know whether adding medicines (called ovulation triggers) that help to release the egg (ovulation) would lead to…
- Trial name
- NCT02264847
- Testing
- Human chorionic gonadotrophin, clomiphene citrate alone
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
PCOS
L-carnitine and Metformin in Obese PCOS Women.
L-carnitine and plus metformin in clomiphene-resistant obese PCOS women, reproductive and metabolic effect: a randomized clinical trial
- Trial name
- NCT03108963
- Testing
- L-carnitine and Metformin
- Where
- Egypt
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Induction of Ovulation
Laparoscopic Ovarian Drilling Versus Letrozole In Clomiphene Citrate Resistant Polycystic Ovary
The aim of this work is to compare the clinical outcomes of letrozole with laparoscopic ovarian drilling (LOD) in patients with clomiphene-citrate-resistant polycystic ovary syndrome (PCOS).
- Trial name
- NCT03664050
- Testing
- group A 2.5 mg letrozole oral tablets, laparoscopic ovarian drilling
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
PCO - Polycystic Ovaries, Infertility
Mild Stimulation Protocol Using Clomiphene Citrate for Women With PCOS Undergoing in Vitro Fertilization
Infertility is of increasing significance affecting almost 48.5 million couples around the world. Anovulation is a major cause of infertility in women with polycystic ovary syndrome (PCOS) accounting for about 80% of women with…
- Trial name
- NCT04157725
- Testing
- mild stimulation protocol: oral Clomiphene Citrate, Conventional Stimulation Protocol: will receive FSH/HMG
- Where
- Lebanon
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Acromegaly
Clomiphene Citrate for Treatment of Acromegaly
To assess the impact of clomiphene citrate on serum insulin like growth factor 1 and testosterone levels in male acromegalic patients not controlled by surgery, radiotherapy and/or medical treatments (somatostatin analogues…
- Trial name
- NCT02274311
- Testing
- Clomiphene Citrate
- Volunteers
- 16 people
- Sponsor
- Felipe Henning Gaia Duarte
Infertility
Comparison Between Letrozole and Laparoscopic Ovarian Drilling in Women With Clomiphene Resistant Polycystic Ovarian Syndrome (PCOS)
140 women with clomiphene resistant PCOS will be randomly divided into 2 equal groups using computer generated random numbers. Group 1 will receive Letrozole, group 2 will have laparoscopic ovarian drilling (LOD).
- Trial name
- NCT02305693
- Testing
- Letrozole, Laparoscopic ovarian drilling
- Where
- 2 sites in Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University
Infertility
Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH Delivered From a Iontophoretic Patch Compared to Oral Treatment With Clomiphene or Placebo in Infertile Females
The primary objective of this study is to determine the safety and efficacy of pulsatile GnRH delivered from a iontophoretic patch (Lutrepatch) for induction of ovulation in women with anovulatory/ oligoovulatory infertility…
- Trial name
- NCT00796289
- Testing
- GnRH iontophoretic transdermal Lutrepatch, clomiphene citrate
- Where
- 35 sites in United States
- Volunteers
- 350 people
- Sponsor
- Ferring Pharmaceuticals
Infertility
Letrozole Versus Laparoscopic Ovarian Drilling in Polycystic Ovary Syndrome
Polycystic ovary syndrome is the major cause of anovulatory infertility. Clomiphene citrate is the most commonly used oral agent for ovulation induction in this group, but there are some drawbacks with the use of it.
- Trial name
- NCT03009838
- Testing
- Letrozole, ovarian drilling
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Female Infertility Due to Nonimplantation of Ovum
Letrozole and Sequential Clomiphene to Improve the Outcome of Embryo Transfer
The purpose of this study is to study the effects of letrozole and sequential clomiphene in ovulation and pregnancy in PCOS patients.
- Trial name
- NCT02775877
- Testing
- Letrozole, clomiphene, HMG
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Navy General Hospital, Beijing
Infertility Treatment, Pregnancy Rates
Effect Clomiphene vs Clomiphene Along With Pioglitazone on Ovarian Stimulation Rate
Women who meet the study requirements will be enrolled and randomly assigned by a computer system to receive either pioglitazone 30 mg daily or a placebo starting from the second day of their menstrual period for the same…
- Trial name
- NCT07462065
- Testing
- Clomiphene Citrate., Pioglitazone (PIO) + Clomiphene citrate
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- PAEC General Hospital, Islamabad
Anovulatory Infertility Related to Polycystic Ovary Syndrome
Strategies for Ovulation Induction in Anovulatory Infertile Patients With PCOS
Anovulatory infertility is a common feature of the polycystic ovary syndrome (PCOS). Even if several first-step treatments have been proposed for anovulatory infertile PCOS patients, very few data are available in literature…
- Trial name
- NCT00461643
- Testing
- Clomiphene citrate, metformin, metformin plus clomiphene citrate, gonadotropins
- Where
- 3 sites in Italy
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Anovulation
Comparison of Anastrozole Verses Clomiphene Citrate in Stimulating Follicular Growth and Ovulation in Infertile Women With Ovulatory Dysfunction
The purpose of this study is to investigate and compare the safety and efficacy of various doses of the aromatase inhibitor (anastrozole) versus clomiphene citrate in stimulating follicular growth and ovulation in infertile women…
- Trial name
- NCT00213148
- Testing
- Anastrozole 1 mg, Anastrozole 5 mg, Anastrozole 10 mg
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- EMD Serono
Testosterone Deficiency
Pharmacokinetic Evaluation of Serum Testosterone Concentrations After Administration of Clomiphene Citrate
This is a randomized, open-label trial examining two doses of clomiphene citrate in men with low serum testosterone concentrations (total testosterone (TT) < 300 ng/dl).
- Trial name
- NCT05096169
- Testing
- Clomiphene Citrate 25mg, Clomiphene Citrate 50mg
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University