Clinical trials: Clotrimazole
Allergic Bronchopulmonary Aspergillosis
A Prospective Study on Optimizing Treatment for ABPA
This study is being done to evaluate the efficacy of treatment using oral glucocorticoid, anti-fungal agent, anti-IgE mAb for patient with ABPA.
- Trial name
- NCT05129033
- Testing
- Prednisone tablet, itraconazole, Omalizumab
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Healthy
Effects of Miconazole on Blood Flow
This study will investigate the effect of the drug miconazole on blood vessel dilation. Miconazole stops production of EDHF, a substance that causes arteries to dilate. EDHF is produced by the cells that line blood vessels.
- Trial name
- NCT00004575
- Testing
- Miconazole, L-NMMA, Bradykinin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV
DDI Potential: Dapivirine Vaginal Ring and Miconazole Nitrate
This trial will investigate the potential drug-drug interaction between dapivirine vaginal Ring-004 and vaginally administered miconazole nitrate, and will evaluate the safety of co-administration of the dapivirine vaginal ring…
- Trial name
- NCT01731574
- Testing
- dapivirine, miconazole
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Vulvovaginal Candidiasis
Patients With Vulvovaginal Candidiasis
The present study aims to evaluate the safety of two mucoadhesive gels containing a propolis standardized extract identified as EPP-AF, with 1 and 2% of propolis.
- Trial name
- EPP-AFG-VVC (NCT03024502)
- Testing
- EPP-AF Gel 1%, EPP-AF Gel 2%, Clotrimazole
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
HIV- Prevention
To Assess the Drug-drug Interaction Potential Between Dapivirine Vaginal Ring-004, Containing 25 mg of Dapivirine, and Clotrimazole 10 mg/g (1%)
A Study to assess the drug-drug interaction potential, between Dapivirine Vaginal Ring-004, containing 25 MG of Dapivirine.
- Trial name
- NCT02847286
- Testing
- Dapivirine Ring-004, Dapivirine Ring-004 for 28 days along with clotrimazole, Clotrimazole
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Endometriosis
Effect of Concomitant Use of an Antimycotic, an Antibiotic, a Spermicide or Tampons on Pharmacokinetics of Anastrozole and Levonorgestrel Released From Intra-vaginal Ring
To investigate the pharmacokinetic effect of a vaginally administered antimycotic (miconazole), antibiotic (clindamycin), spermicide (nonoxynol-9) or the concomitant use of tampons during the use of an intravaginal ring releasing…
- Trial name
- NCT02545452
- Testing
- Anastrozole / Levonorgestrel (BAY98-7196), Gyno-Daktarin, Sobelin vaginal creme
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Bayer
Antifungal Drug Adverse Reaction
An Open-label Study to Evaluate the Effects of Concurrent Administration of Vaginal Antimycotic Medication Miconazole Nitrate on the Pharmacokinetics of Nestorone and Ethinyl Estradiol Delivered by a Contraceptive Vaginal Ring in Normal Ovulating Women
To evaluate the pharmacokinetics (PK) of EE and NES released from the CVR in the presence of a single dose and multiple doses of antimycotic co-medication (miconazole nitrate suppository or cream).
- Trial name
- NCT02215395
- Testing
- NES/EE CVR
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Population Council
Chronic Paronychia
Safety and Efficacy of Intralesional 0.5% Triamcinolone Acetonide in 0.2% Fluconazole Solution vs 0.1% Topical Mometasone Furoate With 2% Miconazole Nitrate Cream in the Treatment of Chronic Paronychia: An Intraindividual Randomized Controlled Trial.
Our objective is to compare the efficacy and safety of intralesional corticosteroids + fluconazole solution to corticosteroid with an antifungal topical preparation, in the management of chronic paronychia.
- Trial name
- NCT07311759
- Testing
- Intralesional triamcinolone acetonide and fluconazole, Topical mometasone furoate and miconazole nitrate, Elica-M®
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University
Otomycosis
Efficacy and Safety Study of Miconazole Oil Versus Vehicle on Fungal Infection of the Ear Canal (Otomycosis)
This study involves two portions, a randomized, double-blind portion and an open-label portion, to evaluate the efficacy and safety of Miconazole oil 2% versus its Vehicle in the treatment of fungal infection of the outer ear…
- Trial name
- NCT04432376
- Testing
- miconazole 2% oil, vehicle oil
- Where
- 12 sites in United States
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Hill Dermaceuticals, Inc.
Otomycosis
Efficacy of Pyodine Soaked Gelfoam vs Single Topical Application of Clotrimazole in Otomycosis Treatment
Background and Objectives To compare the efficacy of gel foam-soaked pyodine with a single topical application of clotrimazole ointment.
- Trial name
- NCT06339294
- Testing
- Clotrimazole Cream, Povidone-Iodine
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Tinea Cruris
Comparative Efficacy of Topical Oxiconazole Cream (1%) Versus Topical Clotrimazole Cream (1%) in the Treatment of Tinea CrurisAbstract
This study is conducted to compare the efficacy of topical oxiconazole 1% cream versus topical clotrimazole 1% cream in patients with tinea cruris.
- Trial name
- NCT07441005
- Testing
- Topical Oxiconazole cream, Topical Clotrimazole cream
- Where
- Pakistan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Healthy
Alternation in the Human Microbiome With Commonly Used Topical Medications
The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients.
- Trial name
- NCT03437005
- Testing
- Desonide 0.05%, Ketoconazole 2%
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy
Uptake of the Antifungal Miconazole and Effect on Estrogen Metabolizing Enzymes in Humans
The purpose of this study, is to study the uptake of the pharmaceutical antifungal miconazole when used as a vaginal suppository in young women.
- Trial name
- NCT00668538
- Testing
- Brentan (miconazole)
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Dermatophytoses
Comparative Study of Topical Oxiconazole 1% Cream Versus Clotrimazole 1% Cream in the Treatment of Dermatophytosis
To compare the efficacy of oxiconazole 1 % cream and clotrimazole cream for treatment of dermatophytosis
- Trial name
- NCT07718685
- Testing
- Oxiconazole Nitrate Cream, Clotrimazole Cream
- Where
- Pakistan
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Shalamar Institute of Health Sciences
Ulcerative Colitis, Pouchitis
Clotrimazole Enemas for Pouchitis in Children and Adults
Colectomy with creation of an ileal pouch (IPAA) is now the treatment of choice for patients with ulcerative colitis that is resistant to existing medical therapies.
- Conditions
- Ulcerative Colitis, Pouchitis, Ileitis, Inflammatory Bowel Disease
- Trial name
- CAPTURE (NCT00061282)
- Testing
- Clotrimazole
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Web