Clinical trials: Cluster Headache
Episodic Cluster Headache, Chronic Cluster Headache
A Study of LY2951742 (Galcanezumab) in Participants With Cluster Headache
The main purpose of this study is to assess the long-term safety and tolerability of galcanezumab administered up to once monthly in participants with episodic or chronic cluster headache who have completed study I5Q-MC-CGAL…
- Trial name
- NCT02797951
- Testing
- Galcanezumab
- Where
- 40 sites in United States, Belgium and 10 more
- Volunteers
- 165 people
- Sponsor
- Eli Lilly and Company
Headache Disorders, Primary, Headache Disorders, Secondary
China Headache and Vertigo Registry Study
In the Chinese Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as vestibular…
- Conditions
- Headache Disorders, Primary, Headache Disorders, Secondary, Migraine, Tension-Type Headache
- Trial name
- CHRS (NCT04939922)
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Episodic Cluster Headache, Chronic Cluster Headache
Sumatriptan 4 mg Statdose in the Acute Treatment of Cluster Headache
This study's hypothesis is the 4mg StatDose sumatriptan is effective for the acute treatment of cluster headache and provides good safety and tolerability across multiple doses of the study medication as well as across multiple…
- Trial name
- NCT00399243
- Testing
- Sumatriptan 4mg Statdose injection
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Diamond Headache Clinic
Cluster Headache
A Study to Explore the Long-Term Safety and Efficacy of Fremanezumab (TEV-48125) for the Prevention of Cluster Headache
This is a 68-week study to evaluate the long-term safety and efficacy of fremanezumab in participants with cluster headache (CH).
- Trial name
- ENFORCE (NCT03107052)
- Testing
- Fremanezumab
- Where
- 83 sites in United States, Australia and 10 more
- Volunteers
- 275 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Trigeminal Neuralgia, Facial Pain
Incidence of Intravascular (IV) Injection During Trigeminal Nerve Blocks
The purpose of this study is to investigate the incidence of intravascular injection during trigeminal nerve blocks.
- Conditions
- Trigeminal Neuralgia, Facial Pain, Postherpetic Neuralgia, Cluster Headache
- Trial name
- NCT04467398
- Testing
- trigeminal nerve block
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University
Cluster Headache, Craniofacial Pain Syndrome
The Presence and Role of Zygomatic-temporal Neuroma Triggering Cluster Headache
Role of a neuroma of zygomatic-temporal in triggering of a cluster headache. Exploratory diagnosis, resection, and pathological examination of tumor anticipated .
- Trial name
- NCT04845451
- Testing
- Minimal surgical exploration for a neuroma
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- FARO T. OWIESY, M.D
Chronic Cluster Headache
Prevention and Acute Treatment of Chronic Cluster Headache Compared to Standard of Care
Subjects enrolled into this 10 week study will for the first two weeks document the number of cluster headaches and the means of treating (medication) of these attacks. Subjects will then be randomized to into either two groups.
- Trial name
- NCT01701245
- Testing
- GammaCore
- Where
- 10 sites in Belgium, Germany and 2 more
- Volunteers
- 97 people
- Sponsor
- ElectroCore INC
Cluster Headache
Botulinum Toxin Type A Block of the Otic Ganglion in Chronic Cluster Headache: Safety Issues
Cluster headache (CH) is the most common of the trigeminal autonomic cephalalgias and one of the most severe pains known to man, having a large impact on the sufferer's quality of life.
- Trial name
- NCT03066635
- Testing
- Botulinum Toxin Type A 25 IU, Botulinum Toxin Type A 12.5 IU
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian University of Science and Technology
Chronic Cluster Headache
A Study of Galcanezumab in Participants With Chronic Cluster Headache
The main purpose of this study is to evaluate the efficacy of the study drug known as galcanezumab in participants with chronic cluster headache.
- Trial name
- NCT02438826
- Testing
- Galcanezumab 300 mg
- Where
- 48 sites in United States, Belgium and 10 more
- Volunteers
- 240 people
- Sponsor
- Eli Lilly and Company
Chronic Cluster Headache
Occipital Nerve Stimulation in Medically Intractable Chronic Cluster Headache
Cluster headache (CH) is a primary headache disorder characterized by recurrent short-lasting attacks (15 to 180 minutes) of excruciating unilateral periorbital pain accompanied by ipsilateral cranial autonomic signs.
- Trial name
- ICON (NCT01151631)
- Testing
- occipital nerve stimulation
- Where
- 7 sites in Belgium, Germany and 2 more
- Volunteers
- 130 people
- Sponsor
- Leiden University Medical Center
Cluster Headache, Pain Management
Pulsed Radiofrequency Combined With Platelet-Rich Plasma Applied to the Sphenopalatine Ganglion in Treating Episodic Cluster Headache
Cluster headache (CH) is one of the most severe pain accompanied by ipsilateral autonomic symptoms such as lacrimation and conjunctival injection.
- Conditions
- Cluster Headache, Pain Management, Episodic Cluster Headache
- Trial name
- NCT06882278
- Where
- China
- Volunteers
- 242 people
- Sponsor
- Beijing Tiantan Hospital
Cluster Headache - Episodic and Chronic, Migraine Headache
Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study
Migraine and/or Cluster Headache: Study Overview Background: Migraine and cluster headache are two primary headache disorders that significantly impact quality of life and functionality in those affected.
- Conditions
- Cluster Headache - Episodic and Chronic, Migraine Headache, Migraine Headache, With or Without Aura, Migraine in Adults
- Trial name
- NCT07292090
- Testing
- Intervention yogabased movements
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Cluster Headache
Prophylactic Treatment of Episodic Cluster Headache
The purpose of this study is to determine whether candesartan cilexetil are effective prophylactic treatment of episodic Cluster headache
- Trial name
- NCT00184587
- Testing
- candesartan cilexetil
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Cluster Headache
A Randomized Multicentre Study for the Acute Relief of Episodic and Chronic Cluster Headache.
The study will look at a non-invasive treatment for people suffering with chronic and episodic headaches. Study subjects will be randomized to an active treatment or an in-active treatment for 2 weeks.
- Trial name
- NCT01958125
- Testing
- gammaCore
- Where
- 9 sites in Denmark, Germany and 2 more
- Volunteers
- 102 people
- Sponsor
- ElectroCore INC
Cluster Headache
Botox Injection in Treatment of Cluster Headache
Cluster headache is an intense and powerful, one-sided headache accompanied by involuntary symptoms such as red eye, droopy eyelids, flow of tears, small pupils and one-sided facial sweating.
- Trial name
- NCT02019017
- Testing
- Botulinum Toxin Type A 25 IU, Botulinum Toxin Type A 50 IU
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian University of Science and Technology
Refractory Chronic Cluster Headache
Cerebral Metabolism in Patients With Refractory Chronic Cluster Headache Treated by Occipital Nerve Stimulation
The occipital nerve stimulation (ONS) is used to treat patients with refractory primary chronic headache but its mechanism of action (MoA) remains unknown.
- Trial name
- MET-ONS (NCT02081482)
- Testing
- 18F-FDG PET
- Where
- 4 sites in France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Cluster Headache
SPG Neurostimulation in Cluster Patients
We hypothesized that LF stimulation of the SPG would increase parasympathetic outflow, activate sensory afferents and provoke a cluster-like attack.
- Trial name
- NCT02510729
- Testing
- Neurostimulation
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Cluster Headache - Episodic and Chronic, Migraine Headache
Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD
Brief Summary: Migraine and/or Cluster Headache: Study Overview Background: Migraine and cluster headache are two primary headache disorders that significantly impact quality of life and functionality in those affected.
- Conditions
- Cluster Headache - Episodic and Chronic, Migraine Headache, Migraine Headache, With or Without Aura, Migraine in Adults
- Trial name
- NCT07348783
- Testing
- Intervention yoga based exercises
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Cluster Headache
Psilocybin for the Treatment of Cluster Headache
The purpose of this study is to investigate the effects of an oral psilocybin pulse regimen in cluster headache. Subjects will be randomized to receive oral placebo, low dose psilocybin, or high dose psilocybin in three…
- Trial name
- NCT02981173
- Testing
- 0.143 mg/kg Psilocybin or 10 mg Psilocybin, 0.0143 mg/kg Psilocybin or 1 mg Psilocybin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Yale University
Migraine, Cluster Headache
mBrain-21 : a Three-month Study on Context-awareness, Physiological Monitoring, and Machine Learning in Migraine and Cluster Headache
This study collects data from migraine and cluster headache patients during a three-month study. Contextual data (e.g. location or smartphone usage) and physiological variables will be used to assist machine learning algorithms…
- Trial name
- MBRAIN-21 (NCT04983186)
- Testing
- Wearable sensor and smartphone application
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent