Clinical trials: Co-design
Anxiety, Depression in Adolescence
Co-designing Adaptations of a Digital Mental Health Intervention (Wysa) for Adolescent Girls With Anxiety or Depression in Rural India
The goal of this study is to culturally and contextually adapt Wysa, an evidence-based AI-powered digital mental health intervention (DMHI), for adolescent girls (ages 13-18) with symptoms of anxiety and/or depression in rural…
- Conditions
- Anxiety, Depression in Adolescence, Anxiety Disorder of Adolescence
- Trial name
- NCT07595029
- Testing
- Digital psychosocial tool
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Wysa
Dementia, Physical Activity
Co-design and Pilot Study in VR-based Physical Activity and Cognitive Training
Physical activity and reminiscence therapy alone have been studied with no clear effectiveness in Alzheimer's disease, but their combined intervention remains unknown.
- Conditions
- Dementia, Physical Activity, Reminiscence Therapy, Co-design
- Trial name
- NCT06982170
- Testing
- A physical activity and reminiscence therapy
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hong Kong University of Science and Technology
No Disease or Condition is Being Studied, Stress Psychological
Supporting Secondary School Student Wellbeing Through a Mobile App and Wearable Biofeedback
This study aims to investigate the effects of an app and wearable device on the wellbeing of secondary school students. The app will offer support for stress management, sleep improvement, and time management.
- Conditions
- No Disease or Condition is Being Studied, Stress Psychological, Overall Wellness
- Trial name
- EWSSS (NCT06294210)
- Testing
- Mobile app and wrist-worn monitor
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Physical Activity
The Use of Data From Wearable Technology to Co-develop School-specific Physical Activity Interventions
Increasing physical activity is vital for children's physical and mental health. It is important to address inactivity early and engage children in positive behaviours which can be sustained throughout life.
- Trial name
- NCT04905615
- Testing
- Data-driven and teacher led school based strategies.
- Where
- United Kingdom
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University of Bath
Lung Cancer
Co-Design and Pilot Testing of Peer-led Community Outreach to Improve Equity, Veteran-Centeredness and Uptake of Lung Cancer Screening
Co-design will be implemented to develop an innovative, Veteran-centered intervention (Vet Peer Connects program) that meets the needs of Black Veterans.
- Trial name
- VPC (NCT06389981)
- Testing
- Veterans peer connect Program
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Youth Mental Health
WeRISE: Youth-led Mental Health Transformation Through Cultivating Gratitude, Kindness, and Hope
The weRISE study's primary aim is to develop and test the effects of an arts-based train-the-trainer intervention developed to cultivate gratitude, kindness, and hope among youth in schools and informal settlements in both India…
- Trial name
- NCT05944263
- Testing
- weRISE; The gratitude, kindness and hope (GKH) program, The [adapted] Stan Kutcher Teen Mental Health (TMH) program
- Where
- 2 sites in India, Kenya
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- citiesRISE
Healthy Subjects
Open, Single Center, Three Periods, Fixed Sequence Design Study on the Effects of Clopidogrel Co-administration on the Pharmacokinetics of Neramexane
Primary: To assess the effects of CYP2B6 inhibition by repeated dose Clopidogrel (75 mg/day) co-administration on the single-dose pharmacokinetics of Neramexane Secondary: To assess safety and tolerability of Neramexane single…
- Trial name
- NCT00936026
- Testing
- Neramexane
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Healthy
This Study in Healthy Men and Women Tests How the Body Takes up BI 409306
The primary objective of this trial is to investigate the absolute bioavailability of BI 409306. The secondary objective is the evaluation and comparison of several pharmacokinetic parameters for the different treatments.
- Trial name
- NCT03505151
- Testing
- BI 409306 (C-13/N-15), BI 409306
- Where
- Germany
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Families, Children
Promotion of Healthy Eating Habits and Physical Activity Among Children and Their Families.
Eating habits and physical activity are key determinants of individual health. The family plays a relevant role in educating children about healthy lifestyles.
- Conditions
- Families, Children, Food Habits, Physical Activity
- Trial name
- ALIAFF (NCT06794411)
- Testing
- Intervention group: Food habits and physical activity program, Usual Care Group
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Research Participation
CO-creating Novel, Feasible, and Inclusive Research Methods
The lessons researchers learn and evidence researchers discover from research studies are limited by who volunteered as participants in each research study.
- Trial name
- CONFIRM (NCT07489144)
- Testing
- Participant co-design
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Augusta University
Healthy
A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 12.5 mg and MET XR 500 mg) in Healthy Volunteers
This is a randomized, open, single-dose, crossover-design, phase 1, single-center study to evaluate bioequivalence after co-administration of ALO and MET XR or administration of CT-L01 in healthy volunteers.
- Trial name
- NCT05363592
- Testing
- CT-L01 12.5/500 mg, Alogliptin Benzoate 12.5 mg, Metformin HCl XR 500 mg
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Celltrion
Autism Spectrum Disorder (ASD), Neurotypical
Autistic Eye Contact?
This research explored both breadth and depth of the experiences with eye contact in adults with and without ASD. A hermeneutic phenomenological multicenter design was used in which 15 adults with ASD and 15 adults without ASD…
- Trial name
- NCT06921876
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Edentulous Mouth
Retention of Computer Aided Design and Computer Aided Manufacturing Titanium Versus Co/Cr Single Dentures.
Steps in short: Undergoing the conventional steps of maxillary single denture construction till the step of framework construction that will be designed and constructed using CAD/CAM after optical scanning of the master cast ( 2…
- Trial name
- NCT03675594
- Testing
- CAD/CAM titanium denture base, CAD/CAM cobalt/chromium denture bases
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Adverse Childhood Experiences
The ACCEPT Study: Improving the Process of Disclosing Adverse Childhood Experiences in Community Mental Health
Experiences of abuse, neglect, domestic violence, severe bullying and community violence in childhood are very common among people who use mental health services.
- Trial name
- NCT06477380
- Testing
- ACCEPT intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King's College London
Bioequivalence Study
Bioequivalence Study of Spironolactone Tablets in Healthy Subjects
The goal of this clinical trial is to Evaluate the Bioequivalence of Spironolactone Tablets 100mg (by SPH Sine Pharmaceutical Laboratories Co.,Ltd) and ALDACTONE® tablets 100mg (by GD SEARLE LLC) in Chinese Healthy Adult…
- Trial name
- NCT06579053
- Testing
- Spironolactone Tablets (Test), Spironolactone Tablets (Reference)
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- SPH Sine Pharmaceutical Laboratories Co., Ltd.
Transition to First-Line Nurse Manager Role
Co-Designed Comprehensive Transition Programme for First-Line Nurse Managers
This study will pilot a Comprehensive Transition Programme (CTP) to support nurses who move into first-line nurse manager (FLNM) roles at Clínica Universidad de Navarra.
- Trial name
- CTP (NCT07191210)
- Testing
- Comprehensive Transition Programme (CTP)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Pregnant Women
Adapted Physical Activity to Promote Quality of Life, Well-being and Physical Activity Levels in Pregnant Women (WELL-DONE!Study)
The aim of the WELL-DONE! Study is to co-design, using different professional figures (midwives, psychologists, master's degree in motor science) but also taking into consideration the pregnant women's point of view, an…
- Trial name
- WELL-DONE! (NCT04735146)
- Testing
- Adapted physical activity
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- First Cycle Degree in Midwifery in collaboration with the Department of Biomedical and Neuromotor Sc
Hyperlipemia, Mixed
Study to Evaluate the Safety and PK of UI018
This Study is to evaluate the safety and pharmacokinetics of a fixed dose combination formulation and co-administration.
- Trial name
- NCT05085184
- Testing
- administration of UI018, co-administration of UIC201806 and UIC201602
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Korea United Pharm. Inc.
Healthy
Phase 1 Study to Compare the Safety, Pharmacokinetic Profiles of CJ-30056 and Lipitor 20mg/Glucophage SR 750mg
This study is designed to evaluate safety and pharmacokinetic properties of the two treatments, the administration of CJ-30056 and the co-administration of atorvastatin 20mg and metformin SR 750mg, in healthy volunteers.
- Trial name
- NCT02378441
- Testing
- Atorvastatin 20mg and Metformin SR 750mg, CJ-30056 20/750mg
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Malignant Melanoma
Co-stimulatory Markers and Vitamin D Status in Anti-PD1 Treated Melanoma Patients
An observational single center study designed to identify response-related biomarkers of anti-programmed death 1 (PD-1) therapy to advanced melanoma patients and to investigate if vitamin D levels are related to treatment…
- Trial name
- NCT03197636
- Testing
- Pembrolizumab
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital