Clinical trials: Cochlear
Hearing Loss, Unilateral, Deafness, Unilateral
Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness
The aim of the study is to assess the continued efficacy and safety of cochlear implantation in participants aged 5 years and above with Unilateral Hearing Loss (UHL)/Single Sided Deafness (SSD) supporting a change indication for…
- Trial name
- PAS-SSD (NCT05318417)
- Testing
- The Cochlear™ Nucleus® Cochlear Implant (CI) System
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Cochlear
Cochlear Implants
Pitch Perception and Memory: Deficits and Training
Pitch perception and memory are central in auditory cognition, in particular for sound source segregation and recognition, speech prosody and music processing.
- Trial name
- Pitch_Train (NCT03707691)
- Testing
- Listening tests. Pitch training protocol, visuo-spatial training protocol, EEG/MEG/MRI recordings.
- Where
- France
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Sensorineural Hearing Loss, Bilateral, Bilateral Hearing Loss
Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting and a Conventional Fitting
Main objective: For a bimodal fitting (hearing aid (HA) + cochlear implant (CI)): Comparison of a tonotopy based fitting strategy (TFS4) to a default fitting strategy (FS4) for the speech recognition in noise.
- Trial name
- NCT05955469
- Testing
- FS4 then TFS4 (cochlear implant), TFS4 then FS4 (cochlear implant)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Cochlear Hearing Loss, Hearing Loss, Sensorineural
Minimizing Facial Nerve Stimulation in Cochlear Implants
This study aims to understand how to manipulate the electrical stimulation from the cochlear implant to maximize hearing stimulation and minimize facial stimulation.
- Conditions
- Cochlear Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Facial Nerve Injury
- Trial name
- NCT04161261
- Testing
- Electrical Stimulation
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Deafness
Neurophysiological Measures of Auditory Perception and Rehabilitation in Cochlear Implanted Patients
This study aims at investigating new automatic fitting techniques for cochlear implant patients based on objective measures. For this reason, the evolution of these neurophysiological measures, expressing the encoding of pure…
- Trial name
- NEUROSYLLABIC (NCT02323256)
- Testing
- Auditory steady-state response ASSR, Speech-ABR, Acoustic Change Complex ACC
- Where
- France
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Deafness, Hearing Loss
Children's Bilateral Cochlear Implantation in Finland
The purpose of this study is to evaluate short and long term outcomes (benefits and side-effects) of bilateral cochlear implantation and bilateral hearing aid rehabilitation in Finnish children.
- Trial name
- FinBiCI (NCT00960102)
- Testing
- cochlear implant, hearing aid
- Where
- 5 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Kuopio University Hospital
Hearing Loss
Cochlear Implant Low Power Strategy
Reducing power consumption in the cochlear implant is crucial to the development of future smaller sound processors. The commercial MP3000 sound coding strategy has been shown to be more efficient in power consumption to the…
- Trial name
- NCT02879539
- Testing
- MP3000 sound coding strategy or ACE strategy with lower stimulation
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- The Hearing Cooperative Research Centre
Cochlear Implant
Place-based Mapping in EAS Listeners
Purpose: Investigate monaural and binaural hearing in electric-acoustic stimulation (EAS) users with place-based versus default maps.
- Trial name
- NCT04722042
- Testing
- place-based mapping, default mapping
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
iotaSOFT Pediatric Study
Prospective, non-randomized, open-label study to evaluate the safety and efficacy of the iotaSOFT Insertion System when used to assist electrode array insertion during cochlear implant surgery in a pediatric population.
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Bilateral, Hearing Loss, Unilateral
- Trial name
- NCT06106373
- Testing
- iotaSOFT Insertion System
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- iotaMotion, Inc.
Hearing Loss, Sensorineural, Severe, Hearing Loss, Sensorineural, Bilateral
Hear Again, Work Again
Project synopsis: This prospective cohort study investigates impact of (1) hearing loss and (2) cochlear implantation on cost and health state on one hand, and employment, productivity and social wellbeing on the other hand in a…
- Conditions
- Hearing Loss, Sensorineural, Severe, Hearing Loss, Sensorineural, Bilateral, Hearing Loss, Unilateral, Hearing Loss, Sensorineural, Profound
- Trial name
- NCT05196022
- Testing
- Cochlear implant
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Hearing Loss, Sensorineural
Investigating Stimulation Parameter and Electrode Mode Changes on Speech Perception in Experienced Adult Cochlear Implant Recipients
This study aims to investigate the effect of stimulation parameters and different electrode modes on speech perception in adult cochlear implant recipients.
- Trial name
- DUAL (NCT06298396)
- Testing
- Program using default MAP, Program using low-power 1 (LP1) MAP, Program using low-power 2 (LP2) MAP
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Cochlear
Performance Prediction
Cochlear-Implant-Performance-Prediction
Despite improved technology, many cochlear implant (CI) recipients still struggle to understand speech in noise (SIN). Because the bottom-up acoustic signal generated by the implant is distorted relative to normal-hearing…
- Trial name
- NCT07564388
- Testing
- cochlear implant user performance prediction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cochlear Implant
The iotaSOFT Insertion System Safety Study
Non-significant risk evaluation of the iotaSOFT Insertion System when used by a surgeon to assist with inserting a cochlear implant electrode array.
- Trial name
- NCT04577118
- Testing
- iotaSOFT Insertion System
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- iotaMotion, Inc.
Hearing Loss, Sensorineural, Cochlear Synaptopathy
Evaluation of the CochSyn Test Prototype to Measure Cochlear Synaptopathy
This study investigates a newly developed test, The CochSyn test that can quantify cochlear synaptopathy (CS) (a new type of sensorineural hearing loss (SNHL)) earlier than the current golden standard pure-tone audiogram.This…
- Conditions
- Hearing Loss, Sensorineural, Cochlear Synaptopathy, Cochlear Hearing Loss
- Trial name
- EarDiTech (NCT06114680)
- Testing
- CochSyn test prototype, Universal Smart Box (USB)
- Where
- Belgium
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hearing Impairment, Sensorineural
CP1150 Sound Processor Speech Perception Compared With the Next Generation of Signal Processing Technology
This clinical study aims to investigate speech performance in quiet with an OTE Sound Processor with modified firmware compared with the commercially available CP1150.
- Trial name
- NCT05286385
- Testing
- CP1150 Sound Processor, CP1150 NF, CP1150 + FF
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Cochlear
Single Sided Deafness
Implantation of the Cochlear® Nucleus® System in Adults With Single-Sided Deafness
The objective of this feasibility study is to obtain preliminary safety and efficacy data associated with cochlear implantation in individuals with severe to profound sensorineural hearing loss contralateral to an ear with…
- Trial name
- NCT01670006
- Testing
- Cochlear Nucleus Cochlear Implant System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cochlear
Sensorineural Hearing Loss, Tinnitus
Effect of a Totally Implantable Cochlear Implant on Tinnitus Severity in Adults With Preoperative Tinnitus
The purpose of this study is to investigate the degree of benefit to tinnitus symptoms by using a Totally Implantable cochlear implant (TICI) in a group of patients who have moderate-to-severe tinnitus pre-operatively.
- Trial name
- EXCITE (NCT07893860)
- Testing
- Cochlear implant
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Cochlear
Sensorineural Hearing Loss, Cochlear Hearing Loss
Listening Effort in Cochlear Implant Users
Listening with a cochlear implant remains difficult and most listeners will report high levels of listening effort.The present study is a "pilot" aiming to evaluate listening effort for cochlear implant users.
- Trial name
- NCT03212924
- Testing
- Pupillometry, Evaluation of speech comprehension in quiet, Evaluation of speech comprehension in noise
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Oticon Medical
Bilateral Cochlear Implants, Hearing Loss, Bilateral
Spatial Cues, Task Demands, and Auditory Selective Attention
Understanding speech in restaurants and other noisy environments is the most common complaint from the more than 60 million Americans with hearing impairment.
- Conditions
- Bilateral Cochlear Implants, Hearing Loss, Bilateral, Healthy
- Trial name
- NCT07765186
- Testing
- Existing bilateral cochlear implants, Normal Hearing Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Hearing Impairment
Evaluation of Carina Microphone Sensitivity and Maximum Stable Gain in Adult Recipients
This investigation is a single-centre, prospective, single-arm, post-market, non-interventional, pilot clinical investigation designed to characterize microphone sensitivity and maximum stable gain of the Cochlear Carina System.
- Trial name
- CAMSEN (NCT04271761)
- Testing
- Non-interventional, post-market, pilot study of Carina Cochlear System
- Where
- Portugal
- Volunteers
- 14 people
- Sponsor
- Cochlear