Clinical trials: Cochlear
Cochlear Implants, Sensorineural Hearing Loss
Anatomy-Based Fitting in Unexperienced Cochlear Implant Users
Severe to profound hearing loss affects 0,8% of the global population. For these people, a conventional hearing aid often does not provide sufficient benefit. However, these people can benefit from a cochlear implant (CI).
- Trial name
- ABFmulti (NCT05451628)
- Testing
- Default CI fitting, Anatomy-based CI fitting
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cochlear Implant, Music
Analysis of Musical and Voice Skills in Children and Adult Cochlear Implant Users
Aims: To evaluate the perception and enjoyment of music in cochlear implant (CI) users using specific questionnaires, and comparing their results with a control group of subjects with normal hearing (NH).
- Conditions
- Cochlear Implant, Music, Voice
- Trial name
- NCT05319678
- Testing
- evaluation with Meludia music software
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz
Hearing Loss, Sensorineural
Intracochlear Platelet-rich Fibrin Application in Cochlear Implantation
Fibrosis due to surgical trauma is a common problem with cochlear implants. Fibrosis limits the effectiveness of implant and increases the power consumption.
- Trial name
- NCT05215197
- Testing
- intracochlear platelet rich fibrin administration
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Pamukkale University
Hearing Loss, Bilateral or Unilateral, Hearing Loss, Sensorineural
A Study to Explore Improved Features and a Simplified Treatment Approach for a Totally Implantable Cochlear Implant (TICI) Research System in Adults With Severe Hearing Loss
This clinical study will test a new investigational totally implanted cochlear implant system (TICI G2). The cochlear implant has an implantable microphone under the skin to detect speech and sound from the environment allowing…
- Conditions
- Hearing Loss, Bilateral or Unilateral, Hearing Loss, Sensorineural, Hearing Loss, Cochlear
- Trial name
- ENHANCE (NCT06642935)
- Testing
- Totally implantable cochlear Implant
- Where
- Australia
- Volunteers
- 18 people
- Sponsor
- Cochlear
Hearing Loss
Optimization of Hearing Performance in the Subject Implanted
In the past two decades, the selection criteria for cochlear implantation have been greatly relaxed so that about 60-70% of present cochlear implant (CI) candidates have significant residual hearing in their contralateral ear.
- Trial name
- OPERSA (NCT05325450)
- Testing
- Program A, Program B, Control
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Cochlear Hearing Loss
Investigation of the Automatic Technology on the Naída M Hearing Devices
In this clinical trial, an un-controlled, repeated measures open design with within-subject comparison will be used to evaluate the effect of the device under investigation on sound perception.
- Trial name
- NCT04610216
- Testing
- Naida CI M hearing device
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Advanced Bionics AG
Single-sided Deafness
Cochlear Implants for Adults With Single-sided Deafness
The purpose of this investigation is to determine the safety and preliminary efficacy of implanting a cochlear implant (CI) in the profoundly deaf ear of an adult with one normal hearing (NH) ear (termed "single-sided deaf"…
- Trial name
- SSD (NCT02259192)
- Testing
- MED-EL Maestro Cochlear Implant
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Robert Shannon
Hearing Impairment
Computer-Assisted Speech Training for Hearing Aid Users
Computer-assisted speech training is a speech recognition training system developed for cochlear implant users. With minimal facilities and skills, cochlear implant users can conduct this training at home.
- Trial name
- NCT02092337
- Testing
- computer-assisted speech training
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Taiwan University Hospital
Hearing Loss, Hearing Impairment
Evaluating Possible Improvement in Speech and Hearing Tests After 28 Days of Dosing of the Study Drug AUT00063 Compared to Placebo (QuicKfire)
The objective of this pilot study is to explore whether repeat doses of AUT00063 can provide an indication of improvement in performance of tests across a battery of speech and hearing assessments in cochlear implant users.
- Trial name
- NCT02832128
- Testing
- AUT00063
- Where
- 4 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- Autifony Therapeutics Limited
Hearing Loss
Perception of Intonation by Bimodal and Bilateral Cochlear Implant Users
The purpose of this study is to evaluate the benefit of bimodal hearing and bilateral cochlear implant hearing in comparison to unilateral cochlear implant hearing in the perception of speech intonation.
- Trial name
- NCT02323932
- Testing
- Perception of correct intonation identification
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Bnai Zion Medical Center
Cochlear Implants, Hearing Preservation
Exploring the Use of ECochG Testing During Electrode Insertion in Cochlear Implant Surgery
Investigation of a new ECoChG system (Electrocochleography) during the surgical insertion of cochlear implants, for patients with Advanced Bionics devices.
- Trial name
- NCT03807830
- Testing
- Electrocochlography
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Profound Bilateral Hearing Loss
Clinical Evaluation of Robot-assisted Cochlear Implant Insertion in Adults Using RobOtol® Compared to Manual Insertion
The purpose of this study is to evaluate, via a randomised controlled design, the efficacy of the robotic insertion of cochlear implant, versus manual insertion. Robotic insertion will be performed using Robotol.
- Trial name
- ROBIICCA (NCT05696171)
- Testing
- Cochlear implant manual insertion, Cochlear implant robotized insertion
- Where
- 14 sites in France
- Volunteers
- 550 people
- Sponsor
- Nantes University Hospital
Language, Development
Language Development in Cochlear Implant Children
The aim of this work is to assess language development in cochlear implanted children in Assiut university hospital and to assess the impact of some related factors (age of implantation, family motivation and education, age of…
- Trial name
- NCT04595552
- Testing
- language therapy
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Assiut University
Hearing Loss, Cochlear Trauma
SPI-1005 in Adults Receiving Cochlear Implant
The goal of this clinical trial is to learn about the effects of drug SPI-1005 in adults receiving a cochlear implant with a long electrode array (FLEX26 or greater) from MED-EL Cochlear Implant Systems into one ear.
- Trial name
- NCT06340633
- Testing
- Ebselen
- Where
- 6 sites in United States
- Volunteers
- 40 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Hearing Loss
ICF in Cochlear Implant Users
The current project proposes a multi-center prospective follow-up cohort study aiming to realize an international framework to classify human functioning and disability in Cochlear Implant (CI) recipients using a standardized ICF…
- Trial name
- NCT04611555
- Where
- 5 sites in Australia, Belgium and 3 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Sensorineural Hearing Loss
The Efficacy of a Minimally Invasive Direct Cochlear Access Via the HEARO Procedure
To study the efficacy of a minimally invasive direct cochlear access via the HEARO procedure.
- Trial name
- ARCI25 (NCT04102215)
- Testing
- HEARO, OTOPLAN
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Prof. Vedat Topsakal
Deafness, Bilateral
Parent-Child Early Approaches to Raising Language Skills (PEARLS) Intervention
The purpose of this research study is to develop and evaluate a parent training program, which aims to improve language. The study is being conducted to see if teaching parents positive parenting techniques and behavior…
- Trial name
- PEARLS (NCT03260062)
- Testing
- Parent-Child Early Approaches to Raising Language Skills, Standard Care Speech therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Miami
Hearing Loss
Combined Acoustic and Electric Hearing (CI/HA) in Adult Bimodal Users Using a HA With a Bimodal Fitting Formula
Introduction: Bilateral-bimodal users may benefit from bilateral-binaural and a bimodal effect . The two modes of stimulation complement each other and may overcome the limitation of electric hearing alone.
- Trial name
- NCT03142100
- Testing
- cochlear implants and hearing aids
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Bilateral Sensorineural Hearing Loss, Cochlear Implant
Binaural Cue Sensitivity in Children and Adults With Combined Electric and Acoustic Stimulation
There is a rapidly growing population of adult and pediatric cochlear implant (CI) recipients with acoustic hearing preservation in the implanted ear(s) allowing for combined Electric and binaural Acoustic Stimulation (EAS).
- Conditions
- Bilateral Sensorineural Hearing Loss, Cochlear Implant, Hearing Preservation, Electric and Acoustic Simulation
- Trial name
- NCT07356128
- Testing
- binaural processing over time, binaural processing over time for children and adults with normal hearing
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hearts for Hearing
Hearing Loss
Outcome Prediction in Cochlear Implant Recipients
The ability to predict post-operative outcomes after implantation is important for a number of reasons, including being able to advise candidates of appropriate expectations using evidence based guidance.
- Trial name
- NCT02984748
- Testing
- Cochlear implant
- Where
- Australia
- Volunteers
- 267 people
- Sponsor
- The Hearing Cooperative Research Centre