Clinical trials: Cochlear Implant
Cochlear Implant, Outcomes
Anatomy-based Fitting in Cochear Implant Users
In this study, the performance with the CI is investigated over time in three groups of freshly implanted CI users. Both the standard frequency-band distribution and anatomy-based fitting will be used to compare outcomes.
- Conditions
- Cochlear Implant, Outcomes, Quality of Life
- Trial name
- NCT05360212
- Testing
- Anatomy-based fitting (ABF), Standard Fitting, Standard fitting+ ABF
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Iowa/Nucleus 10/10 mm and Nucleus Freedom Feasibility Study
The purpose of this study is to evaluate whether the Iowa/Nucleus 10/10 mm in one ear, in conjunction with a Nucleus Freedom implant in the other ear can provide useful binaural hearing in pediatric subjects who have bilateral…
- Trial name
- NCT00594061
- Testing
- Iowa/Nucleus 10/10 mm and Freedom Cochlear Implantation
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Bruce J Gantz
Cochlear Hearing Loss, Hearing Loss, Sensorineural
Minimizing Facial Nerve Stimulation in Cochlear Implants
This study aims to understand how to manipulate the electrical stimulation from the cochlear implant to maximize hearing stimulation and minimize facial stimulation.
- Conditions
- Cochlear Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Facial Nerve Injury
- Trial name
- NCT04161261
- Testing
- Electrical Stimulation
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Hearing Loss
Relationship Between Auto NRT and Behavioural T & C Levels With the Nucleus Freedom Cochlear Implant
Cochlear implants require programming on an individual basis to provide appropriate levels of electrical stimulation. This program, or "map", is placed in the speech processor of the cochlear implant.
- Trial name
- NCT00331539
- Testing
- Cochlear Implant
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Anesthesia
Role of Magnesium in Pediatric Cochlear Implant
To determine the efficiency of addition of magnesium sulfate to total intravenous anesthesia (TIVA) in optimizing the surgical field during pediatric cochlear implant surgery.
- Trial name
- NCT03722940
- Testing
- Magnesium sulphate, Na CL 0.9%
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wahba bakhet
Hearing Loss
Here, My Voice 2 Voice Lessons Pilot
Active music engagement has been shown to provide unique benefits for both pediatric and adult cochlear implant (CI) users. Here, My Voice 2 (HMV 2) project will build upon the 2021 pilot program and provide personalized voice…
- Trial name
- HMV2 (NCT05336747)
- Testing
- Voice lessons
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hearing Loss, Complete
Evaluation of a Bio-inspired Coding Strategy for Cochlear Implant Users
This study will determine the facilitation, refractoriness and spatial spread effects of auditory nerve fiber responses to electrical stimulation via a cochlear implant.
- Trial name
- EBCS (NCT03726684)
- Testing
- Coding strategy for cochlear implants
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Anesthesia, Local
Local Anesthesia for Pediatric Cochlear Implant
Propofol with remifentanil provides good operative conditions for pediatric cochlear implant (CI); however, large doses of remifentanil usually result in postoperative hyperalgesia and increase postoperative pain.
- Trial name
- NCT03721081
- Testing
- Lidocaine 1%/Epi 1:200000, Na Cl 0.9%/Epi 1:200000
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Wahba bakhet
Hearing Loss
A Computational Approach to Optimal Deactivation of Cochlear Implant Electrodes
The goal of the present study is to use computationally driven models of speech understanding in cochlear implant (CI) users to guide the search for which combination of active electrodes can yield the best speech understanding…
- Trial name
- NCT05219474
- Testing
- Cochlear implant Computer Model Implementation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Sensorineural Hearing Loss
Clinical Evaluation of a Cochlear Implant System
The primary objective of this study is to assess the usability of a Cochlear implant system.
- Trial name
- NCT03467399
- Testing
- Nucleus 7 Cochlear Implant System
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cochlear
Cochlear Implant, Children
Effect of Perceptual Training and Phonetic Placement Therapy in Children With Cochlear Implant
Background: Children with cochlear implants often continue to exhibit speech sound and intelligibility difficulties despite improved auditory access.
- Conditions
- Cochlear Implant, Children, Speech Sound Disorder
- Trial name
- NCT07613034
- Testing
- Phonetic placement therapy, perceptual training
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cochlear Implants, Evoked Potentials, Auditory
Optimization of Cochlear Implant MAP-parameters in Children
This project will complete a long-term follow up for children that have received cochlear implants (CI) early in life and had their CI's programmed based on objective measurements.
- Conditions
- Cochlear Implants, Evoked Potentials, Auditory, Child, Disabilities Hearing
- Trial name
- NCT03694340
- Testing
- Re-programming of cochlear implant
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Cochlear Implant, Severe-Profound Hearing Loss
Bimodal, CROS and Severe Profound Hearing Loss Study
The study will involve the comparison of three groups with severe-profound hearing loss. Patients with a Cochlear Implant only, patients with a cochlear implant and Hearing Aid, and finally patients with two hearing aids.
- Conditions
- Cochlear Implant, Severe-Profound Hearing Loss, Hearing Loss, Bilateral, Hearing Loss, Cochlear
- Trial name
- NCT04222296
- Testing
- Fitting strategy of cohlear implant of hearing aid
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Asymmetric Hearing Loss, Single-sided Deafness
Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial
This is a two-phase study that compares performance growth pre-implant with current hearing aid (HA) technology versus post-implant with a cochlear implant (CI) in children with either asymmetric hearing loss (AHL) or…
- Conditions
- Asymmetric Hearing Loss, Single-sided Deafness, Unilateral Deafness
- Trial name
- NCT04793412
- Testing
- Cochlear Implant
- Where
- 5 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Deafness Unilateral
Cochlear Implantation for Young Single-sided Deaf Children
Children with profound sensorineural unilateral hearing loss (UHL) lag behind in spoken language, cognition, spatial hearing, and academic performance compared to normal hearing (NH) children.
- Trial name
- CICADE (NCT04738968)
- Testing
- Cochlear implant
- Where
- 4 sites in Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Deafness
Cerebral Activation and Bilateral Stimulation by Cochlear Implantation in Bilateral Deaf Adults
The primary objective to this study is to describe bilateral auditory information processing in profoundly deaf patients with bilateral cochlear implants compared with normal hearing patients.
- Trial name
- NCT02904187
- Testing
- Positron Emission Tomography (PET), Electroencephalogram (EEG)
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
iotaSOFT Pediatric Study
Prospective, non-randomized, open-label study to evaluate the safety and efficacy of the iotaSOFT Insertion System when used to assist electrode array insertion during cochlear implant surgery in a pediatric population.
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Bilateral, Hearing Loss, Unilateral
- Trial name
- NCT06106373
- Testing
- iotaSOFT Insertion System
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- iotaMotion, Inc.
Hearing Loss, Unilateral
Cochlear Implantation in Pediatric Cases of Unilateral Hearing Loss
This feasibility study evaluates whether children with unilateral, moderate to profound sensorineural hearing loss experience an improvement in speech perception, hearing in noise, localization, and quality of life with a…
- Trial name
- CIPUHL (NCT02963974)
- Testing
- Cochlear implant
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cochlear Hearing Loss
Changes in the Threshold of Electrically Evoked Compound Action Potential in Children Following Cochlear Implantation
After cochlear implantation, cochlear nerve is stimulated by giving a current over the electrodes placed in the cochlea and the current is measured by electrically evoked Compound Action Potential (ECAP).This ECAP is measured…
- Trial name
- NCT03500718
- Testing
- Cochlear implant
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Deafness, Sound Perception
Cochlear Implant Speech and Non-speech Sound Recognition
The primary purpose of the research is to study how synthesized speech and non-speech percepts (sounds) are recognized in subjects with cochlear implants (CI) who are not getting functional speech recognition using existing…
- Conditions
- Deafness, Sound Perception, Quality of Sound
- Trial name
- NCT03661970
- Testing
- Cognate Speech Synthesizer sound percepts
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pacific Northwest University of Health Sciences